Scientists at the US Environmental Protection Agency hope for the best, but fear the worst.
doi: 10.1038/d41586-018-05744-3
Emissions of ozone-destroying chemical blamed on Chinese companies, but origin is yet to be confirmed.
doi: 10.1038/d41586-018-05743-4
Data on the career paths of young researchers would help to guide the ‘lost generation’.
doi: 10.1038/d41586-018-05745-2
When a subatomic particle from space streaked through Antarctica last September, astrophysicists raced to find the source.
doi: 10.1038/d41586-018-05703-y
Privacy concerns and cultural differences make some researchers sceptical that the method could work in other countries.
doi: 10.1038/d41586-018-05728-3
Pilot experiment has seen 26 papers published under open-access terms so far and should yield a report by the end of the year.
doi: 10.1038/d41586-018-05729-2
The planet now has 79 known moons, including a tiny oddball on a collision course with its neighbours.
doi: 10.1038/d41586-018-05725-6
The method could minimize damage from disease if a condition is diagnosed in utero.
doi: 10.1038/d41586-018-05726-5
トランプ政権誕生以降、米国環境保護庁（EPA）の科学者たちは、予算を大きく削減され、不当な扱いを受けながら、不安な毎日を過ごしている。
doi: 10.1038/d41586-018-05706-9
今回、従来の方法で実現できるより高い分解能で撮像し、電子ビームによる損傷を受けやすい脆弱な物質の研究に適した電子顕微鏡が開発された。
doi: 10.1038/d41586-018-05711-y
単一細胞の遺伝子発現パターンの分析によって、冠動脈の成熟につながる発生過程に関する詳しい知見が得られた。
doi: 10.1038/d41586-018-05463-9
今回、最先端の塩基配列解読ツールを用いて、一部の大型類人猿の高品質ゲノム塩基配列がアセンブリーされた。このアセンブリー結果によって、ヒトとそれに進化的に最も近縁な種とを偏りなく比較できるようになった。
doi: 10.1038/d41586-018-05679-9
前立腺がん治療は、治療に対する抵抗性が生まれて失敗することが多い。今回、マウスとヒト細胞の研究から、免疫細胞の集団によってこの種の治療抵抗性が生じることが分かった。
doi: 10.1038/d41586-018-05460-y
北大西洋の循環系は弱まっており、今後数十年間でさらに弱まると予測されている。今回、こうした海洋循環の減速が全球表面の温暖化を加速することが解析によって示された。
doi: 10.1038/d41586-018-05712-x
今回、種の豊富な熱帯よりも、種の密度が低い高緯度域の海洋において、新種の海水魚がより高速で出現することが分かった。新種が定着するには、熱帯は混み合いすぎているのだろうか。
doi: 10.1038/d41586-018-05575-2
Combining an electron microscope pixel-array detector that collects the entire distribution of scattered electrons with full-field ptychography greatly improves image resolution and contrast compared to traditional techniques, even at low beam energies.
doi: 10.1038/s41586-018-0298-5
Analysis of genotyping data for more than 150,000 individuals from the UK Biobank using long-range phase information sheds light on mechanisms of clonal haematopoiesis.
doi: 10.1038/s41586-018-0321-x
During development, new arteries can arise from pre-existing veins; the cell fate switch involved occurs gradually and before the onset of blood flow in mouse embryo hearts.
doi: 10.1038/s41586-018-0288-7
IL-23 produced by myeloid-derived suppressor cells regulates castration resistance in prostate cancer by sustaining androgen receptor signalling.
doi: 10.1038/s41586-018-0266-0
DNA-strand-displacement reactions are used to implement a neural network that can distinguish complex and noisy molecular patterns from a set of nine possibilities—an improvement on previous demonstrations that distinguished only four simple patterns.
doi: 10.1038/s41586-018-0289-6
A robot instructed by a machine learning algorithm and coupled with real-time spectroscopic systems provides fast and accurate reaction outcome predictions and reactivity assessments, leading to the discovery of new reactions.
doi: 10.1038/s41586-018-0307-8
A 26-million-year record of equatorial sea surface temperatures reveals synchronous changes of tropical and polar temperatures during the Eocene epoch forced by variations in concentrations of atmospheric carbon dioxide, with a constant degree of polar amplification.
doi: 10.1038/s41586-018-0272-2
In preindustrial times, a weak Atlantic Meridional Overturning Circulation led to cooling in the Northern Hemisphere, but now it is predicted to cause accelerated global surface warming.
doi: 10.1038/s41586-018-0320-y
Contrary to previous hypotheses, high-latitude fish lineages form new species at much faster rates than their tropical counterparts especially in geographical regions that are characterized by low surface temperatures and high endemism.
doi: 10.1038/s41586-018-0273-1
The career trajectories of around 30,000 artists, film directors and scientists show that individuals in each domain have ‘hot streaks’ during which their works have increased impact, despite showing no increase in productivity.
doi: 10.1038/s41586-018-0315-8
Individuals who are at high risk of developing acute myeloid leukaemia can be identified years before diagnosis using genetic information from blood samples.
doi: 10.1038/s41586-018-0317-6
A non-viral strategy to introduce large DNA sequences into T cells enables the correction of a pathogenic mutation that causes autoimmunity, and the replacement of an endogenous T-cell receptor with an engineered receptor that can recognize cancer antigens.
doi: 10.1038/s41586-018-0326-5
Structural mass spectrometry of full-length human parkin and a structure of the activated parkin core reveal large-scale domain rearrangements involved in activation of parkin by PINK1.
doi: 10.1038/s41586-018-0224-x
Fungal genome mining targeted to self-resistance genes close to biosynthetic gene clusters identifies a pathway that produces aspterric acid, which proves to be a potent inhibitor of plant growth.
doi: 10.1038/s41586-018-0319-4
The cryo-electron microscopy structure of the
doi: 10.1038/s41586-018-0323-8
Mass spectrometry-based assays are used to reveal specificity and structural determinants of lipid binding to class A G-protein-coupled receptors, and the effects of specific lipids on receptor coupling to G proteins.
doi: 10.1038/s41586-018-0325-6
