A transparent process to publish referees’ reports could benefit science, but not all researchers want their assessments made available.
doi: 10.1038/d41586-018-06045-5
Physicists are stripping uncertainty from the loosest fundamental constant — Big G.
doi: 10.1038/d41586-018-06044-6
British Heart Foundation award is one of the largest single grants in medical research.
doi: 10.1038/d41586-018-06068-y
Meteorologist Kelvin Droegemeier offered few clues to his views on the topic when grilled at a US Senate hearing.
doi: 10.1038/d41586-018-06019-7
But academics say government incentives to publish are part of the problem.
doi: 10.1038/d41586-018-06048-2
Health system lacks capacity to respond to attacks that use high-powered modern weapons.
doi: 10.1038/d41586-018-06077-x
How excitement over claims of a high-temperature superconductor reached fever-pitch — and then died away.
doi: 10.1038/d41586-018-06023-x
森林地帯を再生するプロジェクトが世界各地で加速しており、研究者たちは、過去の失敗を繰り返さぬようさまざまな方法を模索している。
doi: 10.1038/d41586-018-06031-x
地震が影響し合う仕組みの解明は、確実な地震予測のカギである。今回、機械学習を用いた研究によって、地震で地質断層に生じた応力変化がこうした相互作用にどのように影響を及ぼすかが明らかになった。
doi: 10.1038/d41586-018-06030-y
今回、全ゲノム塩基配列解読によって、治療抵抗性ヒト前立腺がんのAR遺伝子では、エンハンサーと呼ばれる調節領域が重複していることが明らかになった。この知見は、タンパク質をコードしていないDNA領域の分析が重要であることを示している。
doi: 10.1038/d41586-018-06029-5
今回、遺伝子操作によってSIRT6遺伝子を欠損させたサルは、重度の発生異常を示し、出生後数時間で死亡することが分かった。この知見から、霊長類の発生におけるSIRT6タンパク質のこれまで知られていなかった役割が明らかになった。
doi: 10.1038/d41586-018-05970-9
DNAを転写するRNAポリメラーゼII酵素は、転写初期に停止し、再開のシグナルを待つ。今回、高分解能の構造から、RNAポリメラーゼIIが停止し、その後効率よく再開される仕組みが明らかになった。
doi: 10.1038/d41586-018-05971-8
重力相互作用の強さの基準である重力定数Gは、正確な測定が難しい。今回、2つの独立した方法によって、Gがこれまでになく小さな不確かさで決定された。
doi: 10.1038/d41586-018-06028-6
今回、イネの転写因子OsGRF4を操作して、高収量穀物の一部の窒素利用効率を向上できることが分かった。この発見は、持続可能な農業に影響を及ぼす。
doi: 10.1038/d41586-018-05928-x
Subwavelength-grating metamaterial structures, their main operation principles and their implementation in integrated photonic devices are reviewed.
doi: 10.1038/s41586-018-0421-7
The rapid development of cell culture and animal models has facilitated a new understanding of ZIKV biology and made it possible to generate multiple ZIKV vaccine candidates, which are advancing through clinical trials.
doi: 10.1038/s41586-018-0446-y
The Newtonian gravitational constant is measured with two independent methods, yielding results with relative standard uncertainties of 11.6 parts per million—the lowest uncertainty reported until now.
doi: 10.1038/s41586-018-0431-5
Stimulating the release of serotonin (5-HT) in the nucleus accumbens in wild-type mice promotes sociability, and rescues deficits in social behaviours in a mouse model of autism.
doi: 10.1038/s41586-018-0416-4
The balance of DELLA and GRF4 proteins in plants ensures the co-regulation of growth with metabolism and tipping this balance towards GRF4 leads to higher efficiency of nitrogen use.
doi: 10.1038/s41586-018-0415-5
The cryo-electron microscopy structure of a paused transcription elongation complex of RNA polymerase II bound to DRB sensitivity-inducing factor and negative elongation factor is reported at 3.2 Å resolution.
doi: 10.1038/s41586-018-0442-2
The cryo-electron microscopy structure of an activated transcription elongation complex of RNA polymerase II bound to DRB sensitivity-inducing factor and the elongation factors PAF1 complex and SPT6 is reported at 3.1 Å resolution.
doi: 10.1038/s41586-018-0440-4
The molecular gas in the inner kiloparsec of a submillimetre-bright galaxy is clumpy and gravitationally unstable, collapsing to form stars at a rate that will deplete the gas in about 100 million years.
doi: 10.1038/s41586-018-0443-1
Electron-scattering experiments reveal that the fraction of high-momentum protons in medium-to-heavy nuclei increases considerably with neutron excess, whereas that of high-momentum neutrons decreases slightly, in contrast to shell-model predictions.
doi: 10.1038/s41586-018-0400-z
The domain-wall structure and dynamics are found to enhance, rather than inhibit, the high-frequency performance of an intrinsically tunable material, obtaining ultralow loss and exceptional frequency selectivity.
doi: 10.1038/s41586-018-0434-2
The growth rate of global atmospheric CO2 concentration is faster in drier years, independently of temperature; this relationship is underestimated in current carbon cycle models.
doi: 10.1038/s41586-018-0424-4
Neural networks trained on data from about 130,000 aftershocks from around 100 large earthquakes improve predictions of the spatial distribution of aftershocks and suggest physical quantities that may control earthquake triggering.
doi: 10.1038/s41586-018-0438-y
Experimental data from, and mathematical modelling of, colonies of the clonal raider ant
doi: 10.1038/s41586-018-0422-6
Satellite data for the period 1982–2016 reveal changes in land use and land cover at global and regional scales that reflect patterns of land change indicative of a human-dominated Earth system.
doi: 10.1038/s41586-018-0411-9
Integrated analyses of multiple cohorts are used to obtain a better understanding of the immune state of latent infection with
doi: 10.1038/s41586-018-0439-x
Single-cell RNA sequencing is used to characterize cell types in nasal tissues from human patients with chronic rhinosinusitis, revealing a role for tissue stem cells in allergic inflammatory memory.
doi: 10.1038/s41586-018-0449-8
The Ras-related GTPase RAP2 is a key intracellular signal transducer by which extracellular matrix rigidity controls mechanosensitive cellular activities through YAP and TAZ.
doi: 10.1038/s41586-018-0444-0
A cynomolgus monkey model deficient in SIRT6 protein exhibits severe retardation in prenatal development, in which neuronal differentiation is delayed by activation of the
doi: 10.1038/s41586-018-0437-z
The crystal structure of the Frizzled 4 receptor transmembrane domain is reported to a resolution of 2.4 Å in a ligand-free state.
doi: 10.1038/s41586-018-0447-x
