惑星状星雲HuBi 1の電離構造が「裏返し」になっていることが明らかになり、注目を浴びている。
A star that hides its shine draws admiring looks p.141
Astronomers find a planetary nebula with an unusual structure.
doi: 10.1038/d41586-018-05886-4
Astronomers find a planetary nebula with an unusual structure.
doi: 10.1038/d41586-018-05886-4
A universal vaccine might be some way off, but research into how the immune system responds to the virus will be crucial to achieving that goal.
doi: 10.1038/d41586-018-05885-5
Digital models of the river and surrounding settlements will help authorities to track and reduce waste.
doi: 10.1038/d41586-018-05872-w
Nomination of Kelvin Droegemeier could end long drought at the White House Office of Science and Technology Policy.
doi: 10.1038/d41586-018-05862-y
Haul thrills physicists, who previously knew of just a few hundred of these peculiar materials.
doi: 10.1038/d41586-018-05913-4
The Fields Medals have been awarded to four researchers who work on number theory, geometry and differential equations.
doi: 10.1038/d41586-018-05864-w
Big data and diversity lacking at Germany’s biggest science organization.
doi: 10.1038/d41586-018-05818-2
患者由来の異種移植腫瘍を持つマウスはヒトの治療法開発に役立つ理想的な動物モデルと考えられてきたが、限界があることが明らかになってきた。
doi: 10.1038/d41586-018-05890-8
小児期の最初のインフルエンザウイルス感染は、その後の一生の全てのインフルエンザウイルス感染に対する免疫応答に大きく影響し、この「刷り込み」がいかに重要かが分かってきた。
doi: 10.1038/d41586-018-05889-1
今回、光電子デバイスをポリマーファイバーに組み込む方法が開発された。このファイバーを織って布地を作ることができ、こうした材料は、通信や健康管理に応用できる可能性がある。
doi: 10.1038/d41586-018-05873-9
顧みられない熱帯病のリーシュマニア症には、より優れた治療法が必要である。今回マウスで、リーシュマニア症に有効な化合物が開発されるとともに、この化合物が標的にするタンパク質が特定され、治療法の改善に向けて一歩前進した。
doi: 10.1038/d41586-018-05765-y
今回、一連のリンパ管が血管と相互に作用して、有害な老廃物を脳から除去することが見いだされた。この知見は、認知、加齢、アルツハイマー病などの疾患に関係してくる。
doi: 10.1038/d41586-018-05763-0
強誘電体と呼ばれる物質の電気分極は、内部電場によって抑制されることが多く、こうした物質の用途が制限されている。今回、内部電場の影響を受けにくい薄膜強誘電体が発見された。これは、大きな進歩である。
doi: 10.1038/d41586-018-05807-5
グラフェンナノリボンと呼ばれる物質では、トポロジカル状態を精密に設計し調べることができるため、電子トポロジーを研究する実験プラットフォームが得られる。
doi: 10.1038/d41586-018-05851-1
免疫細胞のインフラマソームタンパク質複合体の活性化は、自然免疫応答の引き金になる重要な段階である。今回、ミトコンドリアDNAの合成と酸化が、この活性化段階を駆動することが分かった。
doi: 10.1038/d41586-018-05764-z
Coherent coupling between a three-electron spin qubit and single photons in a microwave resonator is demonstrated, which, unlike previous demonstrations, does not require ferromagnetic components near the qubit.
doi: 10.1038/s41586-018-0365-y
Meningeal lymphatic dysfunction promotes amyloid-β deposition in the meninges and worsens brain amyloid-β pathology, acting as an aggravating factor in Alzheimer’s disease and in age-associated cognitive decline; improving meningeal lymphatic function could help to prevent or delay age-associated neurological diseases.
doi: 10.1038/s41586-018-0368-8
A series of compounds are discovered for the treatment of visceral leishmaniasis, and cdc2-related kinase 12 (CRK12) is identified as the probable primary drug target.
doi: 10.1038/s41586-018-0356-z
New mitochondrial DNA synthesis links the priming and activation of the NLRP3 inflammasome.
doi: 10.1038/s41586-018-0372-z
A topologically engineered graphene nanoribbon superlattice is presented that hosts a one-dimensional array of half-filled, in-gap localized electronic states, enabling band engineering.
doi: 10.1038/s41586-018-0376-8
Graphene nanoribbons are used to design robust nanomaterials with controlled periodic coupling of topological boundary states to create quasi-one-dimensional trivial and non-trivial electronic quantum phases.
doi: 10.1038/s41586-018-0375-9
A scalable thermal drawing process is used to integrate light-emitting and photodetecting diodes into textile-ready polymer fibres, which can be woven into fabrics with possible optical communication and health monitoring applications.
doi: 10.1038/s41586-018-0390-x
Comparing the northern permafrost region of the Last Glacial Maximum with the same area today shows that the soil carbon stock has now increased, suggesting that permafrost carbon made no net contribution to preindustrial atmospheric carbon.
doi: 10.1038/s41586-018-0371-0
Mantle xenon isotope systematics reveals that no substantial recycling of atmospheric xenon into the deep Earth occurred before 2.5 billion years ago, indicating that downwellings were drier in the Archaean era than today.
doi: 10.1038/s41586-018-0388-4
Similarities between the patterning of the lateral plate in Ciona and of the neural plate ectoderm in vertebrates indicate that compartmentalization of the lateral plate ectoderm preceded the advent of vertebrates.
doi: 10.1038/s41586-018-0385-7
Metagenomic, chemical and biomass analyses of topsoil samples from around the world reveal spatial and environmental trends in microbial community composition and genetic diversity.
doi: 10.1038/s41586-018-0386-6
Mitochondrial double-stranded RNA can induce an interferon response if released into the cytoplasm, but self-recognition is prevented by SUV3 helicase and PNPase exoribonuclease.
doi: 10.1038/s41586-018-0363-0
Human neural stem cells from the subventricular zone are identified as the cells of origin that contain the driver mutations for glioblastomas.
doi: 10.1038/s41586-018-0389-3
A system that targets DNA polymerase activity with CRISPR-guided nickases to provide genetic diversification at user-defined loci enables forward genetic approaches.
doi: 10.1038/s41586-018-0384-8
Selective inhibitors of KAT6A and KAT6B inhibit MYST-catalysed histone acetylation, induce cell cycle exit and cellular senescence without causing DNA damage, and arrest lymphoma progression in mouse models.
doi: 10.1038/s41586-018-0387-5
A cryo-electron microscopy structure of human dynamin-1 demonstrates conformational changes and sheds light on the fission of membranes during endocytosis.
doi: 10.1038/s41586-018-0378-6
A cryo-electron microscopy structure of the mammalian mitochondrial translation initiation complex reveals unique features that are necessary to initiate mitochondrial translation and highlights a possible membrane-targeting peptide.
doi: 10.1038/s41586-018-0373-y