In an uncertain world, more governments are asking universities to help develop weapons. That’s a threat to the culture and conscience of researchers.
doi: 10.1038/d41586-018-04588-1
Nature authors say a reproducibility checklist is a step in the right direction, but more needs to be done.
doi: 10.1038/d41586-018-04590-7
A new set of ethics principles should help researchers and funders do justice to the interests of those involved with Africa’s genomics research.
doi: 10.1038/d41586-018-04589-0
One-third of reefs in the world’s largest coral system were transformed by warmed waters, finds comprehensive underwater and aerial survey.
doi: 10.1038/d41586-018-04660-w
Rapid rise in number of infections and high fatality rate concern researchers.
doi: 10.1038/d41586-018-04486-6
The Environmental Defense Fund is working with researchers at Harvard University on the probe.
doi: 10.1038/d41586-018-04478-6
Low-income sub-Saharan countries bear a high burden of air pollution, but are nearly unrepresented in the research on its health impacts.
doi: 10.1038/d41586-018-04330-x
Researchers deliver 280,000-signature campaign to parliament protesting decade of drastic cuts — but a budget hike might be in their sights.
doi: 10.1038/d41586-018-04523-4
Nations seek to better address future chemical-weapons threats.
doi: 10.1038/d41586-018-04533-2
三次元シミュレーションによって、大質量星が最期にどうして爆発するのかという長年の疑問に答えが出る日が近づいている。
doi: 10.1038/d41586-018-04601-7
患者の体内時計に合わせて薬物を送達するという時間治療が、臨床試験で有望な結果を示したが、実用に向けてはまだ課題がある。
doi: 10.1038/d41586-018-04600-8
脳常在性の免疫細胞は、末梢性の炎症の記憶を長期間保持している。今回、マウスモデルにおいて、この記憶が脳卒中に対する応答やアルツハイマー病の進行に影響を及ぼし得ることが分かった。
doi: 10.1038/d41586-018-03800-6
今回、アミノ酸やペプチドを用いて金ナノ粒子の成長を操作し、偏光を変えるねじれた構造体が作製された。この方法によって、光学デバイスの作製が簡単になる可能性がある。
doi: 10.1038/d41586-018-04205-1
一部の生物種では、雄と雌の姿が著しく異なるものがある。今回、海洋生物化石の研究によって、そうした差異が、絶滅リスクの増大という代償を払って生じていることが見いだされた。
doi: 10.1038/d41586-018-04059-7
今回、フォトニックデバイスと最先端のナノ電子デバイスを集積する方法によって、これまでの限界が克服された。この方法は、高速で低電力のオプトエレクトロニクス技術を実現できる見込みがある。
doi: 10.1038/d41586-018-04443-3
細菌がウイルスに対抗して用いる武器の完全なリストは分かっていない。今回、コンピューターを用いる方法によって、細菌ゲノムの既知の防御遺伝子の近くにある遺伝子によってコードされている、これまで確認されていなかった9つの抗ウイルス系が明らかになった。
doi: 10.1038/d41586-018-04367-y
今回、X線観測によって、銀河系の中心に12個の恒星質量ブラックホールが存在することが明らかになり、さらに数千個存在する可能性が示唆された。この発見は、恒星系力学の重要な予測を裏付けるものである
doi: 10.1038/d41586-018-04341-8
Laser spectroscopy is used to investigate the hyperfine structure and determine the fundamental nuclear properties of the isomer 229mTh, the strongest candidate for the realization of a nuclear clock.
doi: 10.1038/s41586-018-0011-8
Galanin-expressing neurons in the medial preoptic area coordinate different aspects of motor, motivational, hormonal and social behaviour associated with parenting by projecting to different brain regions depending on the type of behaviour and sex and reproductive state of mice.
doi: 10.1038/s41586-018-0027-0
Peripheral stimuli can induce acute immune training and tolerance in the brain and lead to long-lasting epigenetic reprogramming of microglia; these changes alter pathology in mouse models of stroke and Alzheimer’s pathology .
doi: 10.1038/s41586-018-0023-4
Whole-genome sequencing of 1,011 natural isolates of the yeast Saccharomyces cerevisiae reveals its evolutionary history, including a single out-of-China origin and multiple domestication events, and provides a framework for genotype–phenotype studies in this model organism.
doi: 10.1038/s41586-018-0030-5
Observations of NGC 6240 show two differently driven outflows of different gases with a combined outflow rate comparable to the star formation rate, suggesting possible negative feedback on star formation.
doi: 10.1038/s41586-018-0033-2
A way of integrating photonics with silicon nanoelectronics is described, using polycrystalline silicon on glass islands alongside transistors on bulk silicon complementary metal–oxide–semiconductor chips.
doi: 10.1038/s41586-018-0028-z
Molten-salt-assisted chemical vapour deposition is used to synthesize a wide variety of two-dimensional transition-metal chalcogenides.
doi: 10.1038/s41586-018-0008-3
Chirality can be ‘encoded’ into gold nanoparticles by introducing chiral amino acids or peptides during the growth process, leading to the formation of helicoid morphologies.
doi: 10.1038/s41586-018-0034-1
Ostracod species (small, bivalved crustaceans) with high sexual dimorphism, and therefore high male investment, had markedly higher extinction rates than low-investment species, indicating that sexual selection can be a substantial risk factor for extinction.
doi: 10.1038/s41586-018-0020-7
In a ferret model, the microcephaly-associated gene Aspm regulates cortical expansion by controlling the transition of ventricular radial glial cells to more differentiated cell types.
doi: 10.1038/s41586-018-0035-0
Loss of the ribosome-rescue factor Pelo in a subset of mouse epidermal stem cells results in hyperproliferation and altered differentiation of these cells.
doi: 10.1038/s41586-018-0032-3
Non-lysine ubiquitination activity of the E3 ubiquitin ligase MYCBP2 is identified by activity-based profiling; biochemical and structural analysis of MYCBP2 suggests the basis for its mechanism and specificity.
doi: 10.1038/s41586-018-0026-1
Cryo-electron microscopy structures of the evolutionarily conserved core of a fungal INO80 complex bound to the nucleosomal substrate reveal the mechanism underlying nucleosome sliding and histone editing used by this ATP-dependent chromatin remodeller.
doi: 10.1038/s41586-018-0029-y
Cryo-electron microscopy structure of the human INO80 chromatin remodeller in complex with a bound nucleosome reveals that its motor domains are located at the DNA wrap around the histone core.
doi: 10.1038/s41586-018-0021-6
