As research and editorial processes become increasingly open, scientists and editors need to be proactive but also alert to risks.
doi: 10.1038/549431a
A study suggests a possible way to save more species.
doi: 10.1038/549432a
The upcoming referendum is unsettling researchers.
doi: 10.1038/549432b
Even before getting their own lives settled, teams collect information on storm behaviour and their effects on the ecosystem.
doi: 10.1038/549439a
Giant observatory announces long-awaited result.
doi: 10.1038/nature.2017.22655
A new coalition could face battles over gene editing and climate regulations.
doi: 10.1038/nature.2017.22667
Despite close timing, researchers doubt that the first big tremor set off the second.
doi: 10.1038/549442a
When forced to compete for mates, some birds develop longer penises and others almost nothing at all.
doi: 10.1038/nature.2017.22648
Biologists rush to study creatures living beneath Larsen C ice shelf before they disappear.
doi: 10.1038/549443a
広大な化合物の「宇宙」を探査してその中から優れた医薬品を見つけるのに、機械学習とビッグデータが役立ちそうだ。
doi: 10.1038/549445a
ケンブリッジ大学（英国）の物性物理学者Gilbert Lonzarich氏は、材料科学の限界を押し広げ、物質の量子状態の研究に革命をもたらした。
doi: 10.1038/549448a
がん細胞を標的にして脳腫瘍を治療する試みは、臨床的にほとんど成功していない。今回、腫瘍に隣接したニューロンから分泌されるタンパク質の標的化が有効な代替法となる可能性が明らかになった。
doi: 10.1038/nature24141
今回2つの研究によって、地球などの太陽系の岩石惑星の形成時に溶岩の蒸発が生じていたことが示された。これは、激しい衝突が惑星の形成過程に重要な役割を担っていたことを示唆している。
doi: 10.1038/549461a
造血幹細胞における高濃度のビタミンCが、腫瘍抑制タンパク質Tet2への結合を介して、幹細胞の数と機能、そして白血病の発生に影響を及ぼすことが分かった。
doi: 10.1038/nature23548
広く受け入れられている見解では、電子の磁気モーメントと運動量は、重元素でできた物質においてしか強く結合しないとされている。今回、特筆すべき反例が実験的に示された。
doi: 10.1038/549464a
血液前駆細胞の亜集団を異常に拡大させる変異は、白血病を引き起こすことが知られている。今回、遺伝学的解析によって、こうした血液幹細胞のクローン性変異が、固形腫瘍を持つ人々にもよく見られることが分かった。
doi: 10.1038/549465a
妊娠時の感染は、自閉症などの子の神経発達障害のリスクを増大させる。今回、マウスの研究によって、腸内細菌と非定型な脳回路接続との関連が明らかになった。
doi: 10.1038/nature24139
Path-length-dependent axonal synapse sorting of local presynaptic axons of excitatory neurons in the rat medial entorhinal cortex results in sequential targeting of inhibitory and excitatory neurons, which are connected by a cellular feedforward inhibition circuit.
doi: 10.1038/nature24005
Ascorbate depletion in mice increased haematopoietic stem-cell frequency and promoted leukaemogenesis, partly by reducing the function of the Tet2 tumour suppressor enzyme.
doi: 10.1038/nature23876
The authors define a specific cortical subregion of the somatosensory cortex as a critical region of dysfunction that is causal to the emergence of abnormal social and repetitive behaviours in mice exposed to maternal inflammation.
doi: 10.1038/nature23909
Radiation pressure on dusty gas is the main physical mechanism that regulates the distribution of the circumnuclear material that obscures many supermassive black holes.
doi: 10.1038/nature23906
Asymmetry in surface hopping energies in different atomic layers of delafossite oxides results in some of the largest known Rashba-like spin splittings.
doi: 10.1038/nature23898
A polymer code based on a triplet of parameters—network strand length, side-chain length and grafting density—enables materials to be designed with specific combinations of mechanical properties to mimic biological materials.
doi: 10.1038/nature23673
The enzyme LepI is found to be capable of catalysing several natural-product pericyclic transformations, including a hetero-Diels–Alder reaction and a retro-Claisen rearrangement.
doi: 10.1038/nature23882
The pattern of volatile element depletion in the silicate Earth suggests that melting and vaporization on precursor bodies and during accretion were responsible for the volatile element contents of Earth.
doi: 10.1038/nature23645
The measurement of magnesium isotope ratios at improved accuracy suggests that planetary compositions result from fractionation between liquid and vapour, followed by vapour escape during accretionary growth.
doi: 10.1038/nature23899
The authors provide evidence for the existence of life on Earth in the earliest known sedimentary rocks and suggest that the presence of organic carbon, and low stable-isotope values of graphite from sedimentary rocks in Labrador pushes back the existence of organic life to beyond 3.95 billion years.
doi: 10.1038/nature24019
Whole-genome sequencing data of 14,688 Icelanders, including 1,548 parent–offspring trios, show how the age and sex of parents affect the rate and spectrum of de novo mutations.
doi: 10.1038/nature24018
ApoE4 exacerbates tau pathogenesis, neuroinflammation and tau-mediated neurodegeneration independently of brain amyloid-β pathology, and exerts a ‘toxic’ gain of function whereas its absence is protective.
doi: 10.1038/nature24016
Maternal immune activation (MIA)-mediated abnormal behavioural phenotypes require defined gut commensal bacteria for the induction of IL-17-producing T helper 17 cells.
doi: 10.1038/nature23910
The growth of adult and paediatric brain tumours depends on a microenvironmental signalling pathway involving the activity-regulated secretion of neuroligin-3 (NLGN3) from normal neurons and oligodendrocyte precursor cells, highlighting the potential of NLGN3 as a therapeutic target.
doi: 10.1038/nature24014
A novel quantitative approach to identify intact glycopeptides from comparative proteomic data sets, allowing inference of complex glycan structures and direct mapping of them to sites within the associated proteins at the proteome scale.
doi: 10.1038/nature24015
Analysis of global remethylation in mouse embryos at several developmental stages identifies an epigenetic landscape that partitions extraembryonic tissues within the embryo and resembles a frequent, global departure in genome regulation in human cancers.
doi: 10.1038/nature23891
CYREN is a direct inhibitor of classical non-homologous end joining that promotes error-free repair by homologous recombination during the S and G2 phases of the cell cycle.
doi: 10.1038/nature24023
