Editorial
How researchers can help fight climate change in 2022 and beyond p.7
doi: 10.1038/d41586-021-03817-4
News
Afghanistan’s academics despair months after Taliban takeover p.11
doi: 10.1038/d41586-021-03774-y
Webb telescope blasts off successfully — launching a new era in astronomy p.12
doi: 10.1038/d41586-021-03655-4
Journals adopt AI to spot duplicated images in manuscripts p.14
doi: 10.1038/d41586-021-03807-6
The science events to watch for in 2022 p.16
doi: 10.1038/d41586-021-03772-0
News Features
Is precision public health the future — or a contradiction? p.18
doi: 10.1038/d41586-021-03819-2
News & Views
Earth’s eccentric orbit paced the evolution of marine phytoplankton p.27
doi: 10.1038/d41586-021-03549-5
Aggregates of TDP-43 protein spiral into view p.29
doi: 10.1038/d41586-021-03605-0
A heritable, non-genetic road to cancer evolution p.31
doi: 10.1038/d41586-021-03606-z
Mirror symmetry validated for proton and its antimatter twin p.32
doi: 10.1038/d41586-021-03798-4
Review
Iron pnictides and chalcogenides: a new paradigm for superconductivity p.35
doi: 10.1038/s41586-021-04073-2
Articles
A stellar stream remnant of a globular cluster below the metallicity floor p.45
doi: 10.1038/s41586-021-04162-2
An early transition to magnetic supercriticality in star formation p.49
doi: 10.1038/s41586-021-04159-x
A 16-parts-per-trillion measurement of the antiproton-to-proton charge–mass ratio p.53
doi: 10.1038/s41586-021-04203-w
Crystallization of bosonic quantum Hall states in a rotating quantum gas p.58
doi: 10.1038/s41586-021-04170-2
Drop-in fuels from sunlight and air p.63
doi: 10.1038/s41586-021-04174-y
Depressed 660-km discontinuity caused by akimotoite–bridgmanite transition p.69
doi: 10.1038/s41586-021-04157-z
Experimental evidence for recovery of mercury-contaminated fish populations p.74
doi: 10.1038/s41586-021-04222-7
Cyclic evolution of phytoplankton forced by changes in tropical seasonality p.79
doi: 10.1038/s41586-021-04195-7
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues p.85
doi: 10.1038/s41586-021-04217-4
Building an allocentric travelling direction signal via vector computation p.92
doi: 10.1038/s41586-021-04067-0
Transforming representations of movement from body- to world-centric space p.98
doi: 10.1038/s41586-021-04191-x
Local circuit amplification of spatial selectivity in the hippocampus p.105
doi: 10.1038/s41586-021-04169-9
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 p.110
doi: 10.1038/s41586-021-04186-8
Anatomically distinct fibroblast subsets determine skin autoimmune patterns p.118
doi: 10.1038/s41586-021-04221-8
Non-genetic determinants of malignant clonal fitness at single-cell resolution p.125
doi: 10.1038/s41586-021-04206-7
ER proteins decipher the tubulin code to regulate organelle distribution p.132
doi: 10.1038/s41586-021-04204-9
Structure of pathological TDP-43 filaments from ALS with FTLD p.139
doi: 10.1038/s41586-021-04199-3
Time-resolved structural analysis of an RNA-cleaving DNA catalyst p.144
doi: 10.1038/s41586-021-04225-4