A panel striving to alert policymakers to the extinction crisis must address its critics and embrace intellectual diversity.
doi: 10.1038/d41586-018-06007-x
Peer reviewers should not feel pressured to produce a report if key data are missing.
doi: 10.1038/d41586-018-06006-y
Genetic analysis uncovers a direct descendant of two different groups of early humans.
doi: 10.1038/d41586-018-06004-0
The incoming administration promises to use science to alleviate poverty, but it is facing an imminent economic crisis.
doi: 10.1038/d41586-018-05974-5
The Wellcome Trust pulled the grant from Nazneen Rahman, who worked at the Institute of Cancer Research in London.
doi: 10.1038/d41586-018-06009-9
Data from the European Space Agency’s long-awaited Aeolus mission will address one of the biggest gaps in the global forecasting system.
doi: 10.1038/d41586-018-05976-3
Preliminary data suggest that deep-water reefs are more vulnerable to storm threats than researchers had suspected.
doi: 10.1038/d41586-018-06014-y
IPBESでは学際的専門家パネルのイデオロギー対立で、絶滅の危機に瀕した動植物の現状評価と、それを基盤とした生物多様性保全のための国際的な取り組みに暗雲が立ち込めている。
doi: 10.1038/d41586-018-05984-3
今回、RNA塩基配列解読データを使って、単一細胞の各遺伝子について発現の増減やそれらの速度を推定する方法が開発された。このツールには、多くの潜在的用途がある。
doi: 10.1038/d41586-018-05882-8
ある特定の物質は、電気双極子と磁気モーメントの両方を持つ。今回、こうした性質が、これまで知られていなかった方法で結び付けられ、高度な機能性がもたらされる可能性が実験的に実証された。
doi: 10.1038/d41586-018-05982-5
出生後の腸に有益な微生物群集が定着する仕組みは、十分に解明されていない。今回、こうした微生物群集の長期的な組成が、新生マウスの腸細胞のタンパク質によって決定されることが分かった。
doi: 10.1038/d41586-018-05861-z
今回、プログラム可能な超伝導量子ビットアレイによって、量子系の相転移をシミュレートできるようになり、通常のコンピューターではモデル化が困難か非効率的なエキゾチック物理を調べる道が開かれた。
doi: 10.1038/d41586-018-05979-0
がんの増殖を遅らせる薬剤が、インスリンホルモンの濃度を高めることが分かっている。このインスリンの増加が薬剤の有効性を低くするが、今回マウスで、インスリンの量を減らす食餌によって治療の有効性が高まることが明らかになった。
doi: 10.1038/d41586-018-05871-x
CPEB4 binds the mRNA of genes known to be associated with autism and shows an isoform imbalance in individuals with autism, and an equivalent imbalance in mice induces an autism-like phenotype.
doi: 10.1038/s41586-018-0423-5
A cryo-electron microscopy structure of the insect Orco subunit, which forms ion channels with diverse olfactory receptors, reveals a tetrameric cation channel and sheds light on insect olfaction.
doi: 10.1038/s41586-018-0420-8
Cross-correlation analysis of high-resolution spectra obtained as the exoplanet KELT-9b transited its host star reveals neutral and singly ionized atomic iron and singly ionized atomic titanium in the exoplanet’s atmosphere.
doi: 10.1038/s41586-018-0401-y
A large-scale programmable quantum simulation is described, using a D-Wave quantum processor to simulate a two-dimensional magnetic lattice in the vicinity of a topological phase transition.
doi: 10.1038/s41586-018-0410-x
A counter-intuitive state—known as a topological Anderson insulator—in which strong disorder leads to the formation of topologically protected rather than trivial states is realized in a photonic system.
doi: 10.1038/s41586-018-0418-2
The magnetization or polarization of domain states in multiferroics can be reversed while retaining the overall domain pattern, owing to the inherent versatility in coupling the large number of multiferroic order parameters.
doi: 10.1038/s41586-018-0432-4
Elevated rates of reverse weathering within silica-rich oceans led to enhanced carbon retention within the ocean–atmosphere system, promoting a stable, equable ice-free climate throughout Earth’s early to middle ages.
doi: 10.1038/s41586-018-0408-4
A Triassic stem turtle from China has a mixture of derived characters and plesiomorphic features, including an edentulous beak and a rigid puboischiadic plate.
doi: 10.1038/s41586-018-0419-1
Analysis of the El Chichón and Mount Pinatubo volcanic eruptions suggests that solar radiation management strategies using stratospheric sulfate aerosols would do little to counterbalance the effects of climate change on global crop yields.
doi: 10.1038/s41586-018-0417-3
Müller glia in mature mouse retina can be stimulated to produce rod cells; this treatment restores visual responses in a model of congenital blindness.
doi: 10.1038/s41586-018-0425-3
Age-dependent epithelial expression of the innate immune receptor TLR5 in the gut of newborn mice selects against the presence of flagellated bacteria and influences microbiota composition throughout life.
doi: 10.1038/s41586-018-0395-5
RNA velocity, estimated in single cells by comparison of spliced and unspliced mRNA, is a good indicator of transcriptome dynamics and will provide a useful tool for analysis of developmental lineage.
doi: 10.1038/s41586-018-0414-6
Glucose–insulin feedback can reactivate PI3K in tumours treated with PI3K inhibitors, reducing therapeutic efficacy, but this effect can be reduced by using drugs or diet to suppress the insulin response.
doi: 10.1038/s41586-018-0343-4
An autoinhibitory conformation of the histone H3K9 methyltransferase Clr4 of Schizosaccharomyces pombe helps to prevent aberrant heterochromatin formation and maintains epigenetic stability.
doi: 10.1038/s41586-018-0398-2
Inositol hexakisphosphate, which is found in all mammalian cells, binds to two separate sites to promote the assembly and maturation of HIV-1 virus particles.
doi: 10.1038/s41586-018-0396-4
