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RNAが隠し持つ2層目の情報

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分子生物学：RNAが隠し持つ2層目の情報

2014年1月30日 Nature 505, 7485

Principles of RNA primary sequence and secondary structure. <p><b>a</b>, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). <b>b</b>, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports<bibr rid= — Principles of RNA primary sequence and secondary structure.
a, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). b, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)
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Nature ハイライト

find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)
" src="/figures/16895.bmp" />
Principles of RNA primary sequence and secondary structure.
a, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). b, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)

Principles of RNA primary sequence and secondary structure. <p><b>a</b>, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). <b>b</b>, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports<bibr rid= — Principles of RNA primary sequence and secondary structure.
a, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). b, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)
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Nature ハイライト

find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)
" src="/figures/16895.bmp" />
Principles of RNA primary sequence and secondary structure.
a, RNA is a single-stranded polymer, with nucleotide bases adenine (A), cytosine (C), guanine (G) and uracil (U). b, Unlike DNA, RNA molecules do not pair up to form helices. The bases of an individual molecule can therefore pair with one another (G–C and A–U), causing the RNA to fold into secondary structures. G bases can also pair with U bases, forming a G–U wobble pair. Three reports find that such folding is commonplace in humans, plants and yeast. (Figure adapted from Fig. 3 of ref. 4.)

細胞内の全てのRNAについて、折りたたみ方を調べた3つの研究が発表された。RNAには多数の二次構造があることが分かり、その一部は細胞の機能に影響している可能性が明らかになった。

2014年1月30日号の Nature ハイライト

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