Volume 475 Number 7356

Editorials

With strings p.266

doi: 10.1038/475266a

News

Cell signalling caught in the act p.273

doi: 10.1038/475273a

Chip chips away at the cost of a genome p.278

doi: 10.1038/475278a

News Features

High-temperature superconductivity at 25: Still in suspense p.280

doi: 10.1038/475280a

Sports doping: Racing just to keep up p.283

doi: 10.1038/475283a

News & Views

The lessons of Tohoku-Oki p.300

doi: 10.1038/nature10265

Articles

Type VI secretion delivers bacteriolytic effectors to target cells p.343

doi: 10.1038/nature10244

An integrated semiconductor device enabling non-optical genome sequencing p.348

doi: 10.1038/nature10242

The crystal structure of a voltage-gated sodium channel p.353

doi: 10.1038/nature10238

Letters

Sideband cooling of micromechanical motion to the quantum ground state p.359

doi: 10.1038/nature10261

Inkjet printing of single-crystal films p.364

doi: 10.1038/nature10313

Neural network computation with DNA strand displacement cascades p.368

doi: 10.1038/nature10262

Coseismic and postseismic slip of the 2011 magnitude-9 Tohoku-Oki earthquake p.373

doi: 10.1038/nature10227

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking p.377

doi: 10.1038/nature10194

Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis p.381

doi: 10.1038/nature10229

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors p.386

doi: 10.1038/nature10116

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors p.390

doi: 10.1038/nature10263

Protein targeting and degradation are coupled for elimination of mislocalized proteins p.394

doi: 10.1038/nature10181

The ELF4–ELF3–LUX complex links the circadian clock to diurnal control of hypocotyl growth p.398

doi: 10.1038/nature10182

Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP p.403

doi: 10.1038/nature10215

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF p.408

doi: 10.1038/nature10171

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