Volume 461 Number 7265



Chromosome protection scoops Nobel p.706

doi: 10.1038/461706a

Nobel Prize in Physics awarded to light pioneers p.707

doi: 10.1038/461707a

News Features

The disappearing nutrient p.716

doi: 10.1038/461716a

Surfing the wave p.720

doi: 10.1038/461720a

News & Views


Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes p.754

doi: 10.1038/nature08434

Role of the polycomb protein EED in the propagation of repressive histone marks p.762

doi: 10.1038/nature08398


Quantum signatures of chaos in a kicked top p.768

doi: 10.1038/nature08396

Observation of unidirectional backscattering-immune topological electromagnetic states p.772

doi: 10.1038/nature08293

Early Palaeogene temperature evolution of the southwest Pacific Ocean p.776

doi: 10.1038/nature08399

Rapid ascent of rhyolitic magma at Chaitén volcano, Chile p.780

doi: 10.1038/nature08458

Gene therapy for red–green colour blindness in adult primates p.784

doi: 10.1038/nature08401

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity p.788

doi: 10.1038/nature08476

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans p.793

doi: 10.1038/nature08466

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus p.798

doi: 10.1038/nature08463

A genome-wide linkage and association scan reveals novel loci for autism p.802

doi: 10.1038/nature08490

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution p.809

doi: 10.1038/nature08489

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin p.819

doi: 10.1038/nature08448

Structural insights into mechanisms of the small RNA methyltransferase HEN1 p.823

doi: 10.1038/nature08433

Review Article

Finding the missing heritability of complex diseases p.747

doi: 10.1038/nature08494

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