医学研究：MDMAを用いたPTSD治療が、多様な患者群に有効なことが判明

Medical research: MDMA-assisted therapy shown to be effective in diverse group of people

doi: 10.1038/s41591-023-02565-4

COVID-19：血中バイオマーカーでCOVID-19感染後の認知障害を予測

COVID-19: Blood biomarkers may predict cognitive deficits following COVID-19

doi: 10.1038/s41591-023-02525-y

健康：妊娠高血圧腎症の早期予測の質を高める血液由来バイオマーカー

Health: A blood-derived biomarker to enhance the early prediction of preeclampsia

doi: 10.1038/s41591-023-02510-5

Roadblocks to cancer cures

doi: 10.1038/nm1004-1003

Inflamed brains can trigger the blues, studies suggest

doi: 10.1038/nm1004-1007b

Europe',s retired research chimps stranded

doi: 10.1038/nm1004-1006b

Profile: John Hardy

doi: 10.1038/nm1004-1009

Ethical quagmire awaits vaccine for cocaine addiction

doi: 10.1038/nm1004-1007a

News Feature: Mood Swings

doi: 10.1038/nm1004-1010

US panel recommends ',black box', warnings for antidepressants

doi: 10.1038/nm1004-1005b

News In Brief

doi: 10.1038/nm1004-1008

Scientists stumped by dual push for open access, secrecy

doi: 10.1038/nm1004-1006a

Therapeutic cloning gives silenced genes a second voice

doi: 10.1038/nm1004-1005a

The ',neurocentric circle',

doi: 10.1038/nm1004-1039

Biography of a cytologist

doi: 10.1038/nm1004-1040

Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo

doi: 10.1038/nm1004-1013

Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo

doi: 10.1038/nm1004-1014

造血幹細胞の窮乏に対処

Hematopoietic stem cells get closer to the bone

doi: 10.1038/nm1004-1042

骨髄が放つ「脳の殺し屋」

Bone marrow spawns brain killers

doi: 10.1038/nm1004-1044

Historical Research Highlights

doi: 10.1038/nm1004-1054

慢性関節リウマチの自己抗体産生を抑制

Suppressing the self in rheumatoid arthritis

doi: 10.1038/nm1004-1047

VEGFは肺を困らせる悪役にもなる

VEGF obstructs the lungs

doi: 10.1038/nm1004-1041

HISTORICAL NEWS AND VIEWS：脊髄の修復を阻む

Easing the brakes on spinal cord repair

doi: 10.1038/nm1004-1052

忘れじの面影

Memory may not need reminding

doi: 10.1038/nm1004-1045

栄養素センサーは肥満と糖尿病リスクを結ぶ鍵

Nutrient sensor links obesity with diabetes risk

doi: 10.1038/nm1004-1049

Research Highlights

doi: 10.1038/nm1004-1051

非ステロイド性抗炎症薬はAβ₄₂を低減させてプレセニリン1の高次構造を変える

Nonsteroidal anti-inflammatory drugs lower A42 and change presenilin 1 conformation

doi: 10.1038/nm1112

適応度が不均一な多剤耐性結核菌の流行をモデル化する

Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness

doi: 10.1038/nm1110

細胞透過性JNK阻害ペプチドによる新しい糖尿病治療の可能性

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

doi: 10.1038/nm1111

亜硝酸の噴霧状吸入には低酸素感受性でNO依存性の選択的肺血管拡張作用がある

Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator

doi: 10.1038/fake69

亜硝酸の噴霧状吸入には低酸素感受性でNO依存性の選択的肺血管拡張作用がある

p.1122

doi: 10.1038/nm1109

ニューロメジンUはレプチンシグナル経路から独立した新規な食欲減少作用をもつ

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway

doi: 10.1038/nm1106

カンナビノイドのシグナル伝達の異常は胚の卵管輸送を妨げる

Aberrant cannabinoid signaling impairs oviductal transport of embryos

doi: 10.1038/nm1104

血管内皮増殖因子(VEGF)は肺のリモデリングを誘発し、T_H2が仲介する感作と炎症を亢進する

Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung

doi: 10.1038/nm1105

「ホットゾーン」出現のモデル化：結核と薬剤耐性の増幅ダイナミクス

Modeling the emergence of the ',hot zones',: tuberculosis and the amplification dynamics of drug resistance

doi: 10.1038/fake72

骨髄細胞のアデノシンA_2A受容体の選択的不活化または再構成からこれらの受容体が虚血性脳障害の発症に大きくかかわっていることが明らかとなる

Selective inactivation or reconstitution of adenosine A2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury

doi: 10.1038/nm1103

4-1BBを介した慢性関節リウマチの免疫療法

4-1BB-mediated immunotherapy of rheumatoid arthritis

doi: 10.1038/nm1107

セントラルメモリーT細胞はLeishmania majorに対する長期免疫を残留寄生虫が存在しない場合に仲介する

Central memory T cells mediate long-term immunity to Leishmania major in the absence of persistent parasites

doi: 10.1038/nm1108

「ホットゾーン」出現のモデル化：結核と薬剤耐性の増幅ダイナミクス

p.1111

doi: 10.1038/nm1102

ボリュームCT(VCT)：非侵襲的で高解像度の腫瘍血管新生モニター技術

Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis

doi: 10.1038/nm1101