The earliest known drawing in history sends a message through 73,000 years p.149

Cross-hatched crayon on a rock shard suggests early humans indulged in abstract art.

doi: 10.1038/d41586-018-06657-x


Celebrate the mathematics of Emmy Noether p.149

An algebra pioneer who faced discrimination deserves wider recognition on the centenary of her namesake theorem.

doi: 10.1038/d41586-018-06658-w


Pakistan’s prosperity needs independent experts p.150

Imran Khan’s new administration must respect expertise to meet its ambitious goals.

doi: 10.1038/d41586-018-06659-9



Raging wildfires send scientists scrambling to study health effects p.157

Blazes have created natural experiments in Montana and California towns and a monkey-breeding colony.

doi: 10.1038/d41586-018-06123-8


South Africa pushes science to improve daily life p.158

Sweeping policy changes aim to refocus research efforts on poverty, unemployment, drought and other national problems.

doi: 10.1038/d41586-018-06122-9


India’s surprise plan to send people to space by 2022 p.160

But experts say the mission is a huge task and could detract from more useful space programmes.

doi: 10.1038/d41586-018-06146-1

パルサーの発見と卓越したリーダーシップが評価され、女性天体物理学者Jocelyn Bell Burnellに、基礎物理学ブレイクスルー賞の特別賞が。

Pulsar discoverer Jocelyn Bell Burnell wins $3-million Breakthrough Prize p.161

Astrophysicist plans to spend prize money — awarded 50 years after the discovery — on increasing diversity in science.

doi: 10.1038/d41586-018-06210-w


Google unveils search engine for open data p.161

The tool, called Google Dataset Search, should help researchers to find the data they need more easily.

doi: 10.1038/d41586-018-06201-x

News Features


How to stop data centres from gobbling up the world’s electricity p.163


doi: 10.1038/d41586-018-06610-y

News & Views


Receptor becomes a ligand to control bone remodelling p.180


doi: 10.1038/d41586-018-05960-x


Spins travel far in an antiferromagnet p.181


doi: 10.1038/d41586-018-06197-4


A 3D cell shape that enables tube formation p.182

胚では、上皮と呼ばれる細胞のシートが湾曲して管になることがある。今回、モデル化とin vivo観察によって、これまでのいくつかの仮説に反して、管の細胞がscutoidと名付けられた非対称な細胞形状をとることが明らかになった。

doi: 10.1038/d41586-018-06162-1


Future of tidal wetlands depends on coastal management p.183


doi: 10.1038/d41586-018-06190-x


Elusive mitochondrial connection to inflammation uncovered p.185


doi: 10.1038/d41586-018-05988-z


Protein complexes assemble as they are being made p.186


doi: 10.1038/d41586-018-05905-4



Optimized arylomycins are a new class of Gram-negative antibiotics p.189

Chemical optimization of arylomycins results in an inhibitor of bacterial type I signal peptidase that shows activity both against multidrug-resistant clinical isolates of Gram-negative bacteria in vitro and in several in vivo infection models.

doi: 10.1038/s41586-018-0483-6


Coupling of bone resorption and formation by RANKL reverse signalling p.195

Osteoclasts secrete small extracellular vesicles that stimulate osteoblasts, promoting bone formation via receptor activator of nuclear factor-kappa B ligand (RANKL), thereby linking bone formation and resorption.

doi: 10.1038/s41586-018-0482-7


Precancerous neoplastic cells can move through the pancreatic ductal system p.201

Comparison of multiple lesions from individual pancreases sheds light on how ancestral clones can spread through the ductal system and give rise to precursor lesions, with acquisition of further mutations leading to pancreatic cancer.

doi: 10.1038/s41586-018-0481-8



Autogenous and efficient acceleration of energetic ions upstream of Earth’s bow shock p.206

Observations of a hot flow anomaly accelerating solar-wind ions suggest a mechanism for such acceleration—a Fermi acceleration trap caused by Earth’s bow shock interacting with the solar wind.

doi: 10.1038/s41586-018-0472-9


Observation of the 1S–2P Lyman-α transition in antihydrogen p.211

The observation of the 1S–2P Lyman-α transition in the antihydrogen atom, the antimatter counterpart of hydrogen, is reported.

doi: 10.1038/s41586-018-0435-1


Hundred-fold enhancement in far-field radiative heat transfer over the blackbody limit p.216

Rates of radiative heat transfer between sub-wavelength planar membranes are experimentally and theoretically shown to exceed the blackbody limit in the far field by more than two orders of magnitude.

doi: 10.1038/s41586-018-0480-9


Tunable long-distance spin transport in a crystalline antiferromagnetic iron oxide p.222

Tunable spin transport over long distances is demonstrated through the antiferromagnetic insulator haematite, paving the way to the development of spin-logic devices based on antiferromagnetic insulators.

doi: 10.1038/s41586-018-0490-7


Three-dimensional printing of hierarchical liquid-crystal-polymer structures p.226

3D printing of liquid-crystal polymers can create lightweight hierarchical structures with very high stiffness and toughness.

doi: 10.1038/s41586-018-0474-7


Future response of global coastal wetlands to sea-level rise p.231

A global modelling approach shows that in response to rises in global sea level, gains of up to 60% in coastal wetland areas are possible, if appropriate coastal management solutions are developed to help support wetland resilience.

doi: 10.1038/s41586-018-0476-5


Stepwise and independent origins of roots among land plants p.235

Meristems of the rooting axes of Asteroxylon mackiei preserved in 407-million-year-old Rhynie chert lack root caps, which demonstrates that the evolution of the root systems of modern vascular plants occurred in a stepwise fashion.

doi: 10.1038/s41586-018-0445-z


Sensing with tools extends somatosensory processing beyond the body p.239

Tools are embodied by the human somatosensory system, serving as sensory extensions of the human body.

doi: 10.1038/s41586-018-0460-0

幹細胞:創傷部に存在する細胞のin vivo再プログラム化により皮膚上皮組織を作り出す

In vivo reprogramming of wound-resident cells generates skin epithelial tissue p.243

Four transcription factors that specify keratinocyte cell fate, facilitate in vivo reprogramming of wound-resident mesenchymal cells, epithealization and regeneration of skin epithelial tissues in mice.

doi: 10.1038/s41586-018-0477-4


Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling p.248

The plant receptor kinase co-receptor BAK1 contains phosphosites that are required for immune function but not for brassinosteroid-regulated growth in Arabidopsis thaliana; an additional tyrosine phosphosite may be required for the function of many Arabidopsis receptor kinases.

doi: 10.1038/s41586-018-0471-x


An orthogonal proteomic survey uncovers novel Zika virus host factors p.253

Integrative analyses identify host proteins that are modulated by Zika virus at multiple levels and provide a comprehensive framework for the understanding of Zika virus-induced changes to cellular pathways.

doi: 10.1038/s41586-018-0484-5


Parkin and PINK1 mitigate STING-induced inflammation p.258

Acute and chronic mitochondrial stress in mice require PINK1 and parkin to restrain STING-mediated innate immunity.

doi: 10.1038/s41586-018-0448-9


GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis p.263

During starvation, glyceraldehyde 3-phosphate dehydrogenase (GAPDH) targets GTPase-activating proteins to inhibit multiple intracellular transport pathways, thereby promoting energy homeostasis.

doi: 10.1038/s41586-018-0475-6


Cotranslational assembly of protein complexes in eukaryotes revealed by ribosome profiling p.268

Cotranslational assembly is a prevalent mechanism for the formation of oligomeric complexes in Saccharomyces cerevisiae, with one subunit serving as scaffold for the translation of partner subunits.

doi: 10.1038/s41586-018-0462-y

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