Challenge anti-Semitism p.407
A wave of anti-Jewish prejudice is once again washing over schools and universities. There is no excuse not to call out this vile behaviour.
doi: 10.1038/d41586-018-04926-3
A wave of anti-Jewish prejudice is once again washing over schools and universities. There is no excuse not to call out this vile behaviour.
doi: 10.1038/d41586-018-04926-3
As officials meet in Bonn to swap stories on progress towards the Paris goals, only emissions cuts will guarantee a happy ending.
doi: 10.1038/d41586-018-04925-4
Results from a Nature photo competition show the power of images.
doi: 10.1038/d41586-018-04924-5
New climate-inequality tool quantifies how quickly the weather will veer beyond normal in different regions.
doi: 10.1038/d41586-018-04854-2
Young researchers who narrowly miss out on postdoctoral grant struggle to compete with those who just qualify.
doi: 10.1038/d41586-018-04958-9
Images from Landsat satellites and agricultural-survey programme are freely available to scientists — but for how long?
doi: 10.1038/d41586-018-04874-y
With a move from London to Amsterdam less than a year away, the European Medicines Agency is facing uncertainty.
doi: 10.1038/d41586-018-04917-4
Researchers hope European–Russian Trace Gas Orbiter will end a long-running debate over source of the gas on Mars.
doi: 10.1038/d41586-018-04948-x
Direct sequencing of RNA molecules such as virus genomes should help to unpick role of mysterious chemical modifications.
doi: 10.1038/d41586-018-04908-5
Clean energy is growing quickly. But time is running out to rein in carbon emissions.
doi: 10.1038/d41586-018-04931-6
Scientists want to combat dementia and neurodegeneration by keeping the brain’s immune system from going rogue.
doi: 10.1038/d41586-018-04930-7
A catalyst has been developed that recognizes the topology of just one face of a planar reaction intermediate. Remarkably, this enables one mirror-image isomer of the reaction product to be made selectively.
doi: 10.1038/d41586-018-04684-2
An epidemiological study of adolescents who had acquired HIV around the time of birth highlights how high-income countries benefit from the ability to begin treating all infected children in the first years of life.
doi: 10.1038/d41586-018-04476-8
Migration of brine shrimp causes substantial mixing of the water column.
doi: 10.1038/d41586-018-04673-5
Single-cell analyses in cancer are limited by the small biomass of individual cells. In vitro production of 3D organoid structures from single tumour-derived cells generates sufficient biomass for in-depth analyses.
doi: 10.1038/d41586-018-03841-x
Cancers of epithelial-cell origin often contain some tumour cells that have acquired traits of mesenchymal cells. How this leads to cancer spread has now been illuminated in mouse models.
doi: 10.1038/d41586-018-04403-x
Two experiments have demonstrated entanglement — non-classical correlations — between remote mechanical systems comprising billions of atoms. The results could advance our understanding of quantum physics.
doi: 10.1038/d41586-018-04827-5
A neuronal population has now been found that regulates two competing needs — hunger and pain. Urgent pain overrides hunger, but appetite-inducing neuronal activity dampens long-term pain responses to enable feeding.
doi: 10.1038/d41586-018-04759-0
Cooperation between a chiral hydrogen-bond-donor catalyst and a strong Lewis-acid promoter in an SN1-type reaction mediates the formation of tertiary carbocations and enables control over enantioselectivity and product distribution.
doi: 10.1038/s41586-018-0042-1
A new version of the phylogenetic bootstrap method enables assessment of the robustness of phylogenies that are based on large datasets of hundreds or thousands of taxa.
doi: 10.1038/s41586-018-0043-0
Organoids derived from individual cells from colorectal cancers and adjacent normal tissue are used to investigate intra-tumour diversification at the genomic, epigenetic and functional levels.
doi: 10.1038/s41586-018-0024-3
Epithelial-to-mesenchymal transition in tumour cells occurs through distinct intermediate states, associated with different metastatic potential, cellular properties, gene expression, and chromatin landscape
doi: 10.1038/s41586-018-0040-3
Observations of carbon monoxide and ionized carbon lines from the source SPT2349-56 show it to contain a cluster of at least fourteen gas-rich galaxies with redshifts of 4.31, in a highly dense core region.
doi: 10.1038/s41586-018-0025-2
Remote quantum entanglement is demonstrated in a micromachined solid-state system comprising two optomechanical oscillators across two chips physically separated by 20 cm and with an optical separation of around 70 m.
doi: 10.1038/s41586-018-0036-z
Quantum entanglement is demonstrated in a system of massive micromechanical oscillators coupled to a microwave-frequency electromagnetic cavity by driving the devices into a steady state that is entangled.
doi: 10.1038/s41586-018-0038-x
Ohmic losses in plasmonic devices can be reduced by exploiting ‘resonant switching’, in which light couples to surface plasmon polaritons only when in resonance and bypasses them otherwise.
doi: 10.1038/s41586-018-0031-4
During continent collision and associated mountain building, a surprisingly large volume of the lower crust is shown to be affected by earthquake aftershocks, producing a top-down effect on crustal geodynamics.
doi: 10.1038/s41586-018-0045-y
Acute heat stress from the extended marine heatwave of 2016 is a potent driver of the transformation of coral assemblages, which affects even the most remote and well-protected reefs of the Great Barrier Reef.
doi: 10.1038/s41586-018-0041-2
Laboratory experiments with the brine shrimp Artemia salina illustrate the potential for turbulence generated by the diurnal vertical migrations of aggregations of centimetre-scale zooplankton to affect the physical and biogeochemical structure of oceanic water columns.
doi: 10.1038/s41586-018-0044-z
The immunoregulatory metabolite itaconate and its dimethyl derivative induce electrophilic stress and react with glutathione to induce both Nrf2-dependent and Nrf2-independent responses, resulting in AF3-mediated inhibition of the inflammation-related protein IκBζ.
doi: 10.1038/s41586-018-0052-z
A subset of neurons in the hypothalamus is identified as the primary site of action for regulating energy balance and glucose homeostasis by leptin.
doi: 10.1038/s41586-018-0049-7
Binding of an ES cell-specific transcription factor pre-marks cell-type-restricted enhancers in ES cells, and this premarking is required for the robustness of enhancer activation in differentiated cells.
doi: 10.1038/s41586-018-0048-8
A high-resolution X-ray structure and molecular dynamics simulations of the N-methyl-d-aspartate receptor in complexes with channel-blocking ligands reveals the molecular basis of the ligand binding and channel block.
doi: 10.1038/s41586-018-0039-9
Crystal structures of the neuropeptide Y1 receptor in complex with two distinct antagonists combined with NMR, molecular docking and mutagenesis studies inform a proposed model for receptor–agonist binding.
doi: 10.1038/s41586-018-0046-x