Volume 541 Number 7638



Gender imbalance in science journals is still pervasive p.435

The latest update on Nature’s sexism shows an increase in female contributors and referees since 2012, but there is a long way to go.

doi: 10.1038/541435b


Scientists must fight for the facts p.435

President Trump’s unconventional stances cannot go unchallenged.

doi: 10.1038/541435a

さまざまな国、団体、製薬企業が参加し、新興感染症のワクチン備蓄を目指すCEPI(Coalition for Epidemic Preparedness Innovations)は、称賛に値する。

Vaccine initiative marks bold resolution p.436

Preparation against future epidemic threats is a welcome and essential move.

doi: 10.1038/541436a



Trump’s next move? Scientists struggle with foggy future p.443

The US president reiterated his promise to roll back climate regulations on his first day in office.

doi: 10.1038/nature.2017.21339


Billion-dollar project aims to prep vaccines before epidemics hit p.444

Massive effort plans to stockpile vaccines against future outbreaks.

doi: 10.1038/nature.2017.21329


Plant biologists welcome their robot overlords p.445

Old-school areas of plant biology are getting tech upgrades that herald more detailed, faster data collection.

doi: 10.1038/541445a


‘You never said my peer review was confidential’ — scientist challenges publisher p.446

Open-science advocate says journals should be clearer to peer-reviewers about terms and conditions.

doi: 10.1038/nature.2017.21342


D-Wave upgrade: How scientists are using the world’s most controversial quantum computer p.447

Scepticism surrounds the ultimate potential of D-wave machines, but researchers are already finding uses for them.

doi: 10.1038/541447b


Biotech firm backs controversial CRISPR challenger p.447

What Novozymes might do with the NgAgo protein, claimed by some to be a powerful gene editor, is still unclear.

doi: 10.1038/nature.2017.21343


Controversial patient-consent proposal left out of research-ethics reforms p.449

US agency releases finalized ‘Common Rule’, which governs human-subjects research.

doi: 10.1038/nature.2017.21330

News Features


Big science has a buzzword problem p.450


doi: 10.1038/541450a

News & Views


Virology: Phages make a group decision p.466


doi: 10.1038/nature21118


Physics: Optical transition seen in antihydrogen p.467


doi: 10.1038/541467a


Planetary science: Earth's building blocks p.468


doi: 10.1038/541468a


Materials science: Versatile gel assembly on a chip p.470


doi: 10.1038/nature21491


Cell biology: Unconventional translation in cancer p.471


doi: 10.1038/nature21115




Neurotoxic reactive astrocytes are induced by activated microglia p.481

A reactive astrocyte subtype termed A1 is induced after injury or disease of the central nervous system and subsequently promotes the death of neurons and oligodendrocytes.

doi: 10.1038/nature21029


Communication between viruses guides lysis–lysogeny decisions p.488

Some phages—viruses that infect bacteria—encode peptides that are secreted from infected cells and that, beyond a certain threshold, stimulate other viruses to switch from the lytic (killing the host cell) to lysogenic (dormant) phase.

doi: 10.1038/nature21049


Translation from unconventional 5′ start sites drives tumour initiation p.494

The translation of upstream open reading frames in skin tumour models protects some cancer-related mRNAs from global reductions in protein synthesis during the early stages of tumour initiation, suggesting that unconventional translation has a crucial role in tumorigenesis.

doi: 10.1038/nature21036


Structure of a CLC chloride ion channel by cryo-electron microscopy p.500

Some CLC proteins are channels that conduct chloride ions passively, whereas others are active co-transporters, a difference that has been hard to understand given their high degree of sequence homology; now, cryo-electron microscopy is used to determine the structure of a mammalian CLC channel, shedding light on this question.

doi: 10.1038/nature20812



Observation of the 1S–2S transition in trapped antihydrogen OPEN p.506

The 1S–2S transition in magnetically trapped atoms of antihydrogen is observed, and its frequency is shown to be consistent with that expected for hydrogen.

doi: 10.1038/nature21040


High-spatial-resolution mapping of catalytic reactions on single particles p.511

The chemical conversion of N-heterocyclic carbene molecules attached to catalytic particles is monitored at high spatial resolution using synchrotron-radiation-based infrared nanospectroscopy.

doi: 10.1038/nature20795


Compensatory water effects link yearly global land CO2 sink changes to temperature p.516

A study of how temperature and water availability fluctuations affect the carbon balance of land ecosystems reveals different controls on local and global scales, implying that spatial climate covariation drives the global carbon cycle response.

doi: 10.1038/nature20780


The isotopic nature of the Earth’s accreting material through time p.521

The mantle signatures of elements with distinct affinities for metal isotopically record different stages of Earth’s accretion, revealing that the Moon-forming impactor had a similar composition to the other impactors that made the Earth.

doi: 10.1038/nature20830


Ruthenium isotopic evidence for an inner Solar System origin of the late veneer p.525

All chondrites are shown to have Ru isotopic compositions that are more different from that of the Earth’s mantle the further from the Sun they formed; this means the Earth’s late veneer cannot derive from volatile-rich material formed in the outer Solar System.

doi: 10.1038/nature21045


Breeding site sampling across the Arctic by individual males of a polygynous shorebird p.528

Nomadic movement across the breeding range enables male pectoral sandpipers to display and sire offspring at multiple sites within a single breeding season, with tenure depending on breeding female numbers at each site.

doi: 10.1038/nature20813


A solution to the single-question crowd wisdom problem p.532

The wisdom of the crowd can be improved by using an algorithm that selects the answer that is more popular than people predict, rather than the answer that is most popular.

doi: 10.1038/nature21054

進化学:低温に適応した珪藻Fragilariopsis cylindrusの進化ゲノミクス

Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus OPEN p.536

The genome of the Southern Ocean phytoplankton Fragilariopsis cylindrus differs markedly from the genomes of its more temperate relatives, with divergent alleles being differentially expressed in environmentally specific conditions such as freezing and darkness.

doi: 10.1038/nature20803

幹細胞:HippoキナーゼLATS1とLATS2は ERαとのクロストークを介してヒト乳腺細胞の運命を制御する

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα p.541

Ablation of the large tumour suppressor kinases 1 and 2 promotes a luminal breast cell phenotype through stabilization of oestrogen receptor-α, thereby changing human breast cell fate.

doi: 10.1038/nature20829


Structural basis for ArfA–RF2-mediated translation termination on mRNAs lacking stop codons p.546

The structure of the bacterial ribosome stalled on a truncated mRNA in complex with ArfA and the release factor RF2 is presented, revealing how ArfA recruits RF2 to the ribosome and induces conformational changes within RF2 to enable translation termination in the absence of a stop codon.

doi: 10.1038/nature20821


Mechanistic insights into the alternative translation termination by ArfA and RF2 p.550

The structure of the bacterial 70S ribosome in complex with ArfA, the release factor RF2, a short non-stop mRNA and a cognate P-site tRNA is presented, revealing how ArfA and RF2 facilitate alternative translation termination of the non-stop ribosomal complex using a stop-codon surrogate mechanism.

doi: 10.1038/nature20822


Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome p.554

The structure of the bacterial ribosome in complex with the ArfA and the release factor RF2 shows how ArfA recruits RF2 to terminate translation of messenger RNAs that lack a stop codon in the ribosome.

doi: 10.1038/nature21053

「Journal home」に戻る