Research Abstract


Photoswitchable gel assembly based on molecular recognition

2012年1月3日 Nature Communications 3 : 603 doi: 10.1038/ncomms1617


山口 浩靖1, 小林 裕一郎1, 小林 亮介1, 高島 義徳1, 橋爪 章仁1 & 原田 明1,2

  1. 大阪大学大学院 理学研究科 高分子科学専攻
  2. 科学技術振興機構(JST)戦略的創造研究推進事業(CREST)
The formation of effective and precise linkages in bottom-up or top-down processes is important for the development of self-assembled materials. Self-assembly through molecular recognition events is a powerful tool for producing functionalized materials. Photoresponsive molecular recognition systems can permit the creation of photoregulated self-assembled macroscopic objects. Here we demonstrate that macroscopic gel assembly can be highly regulated through photoisomerization of an azobenzene moiety that interacts differently with two host molecules. A photoregulated gel assembly system is developed using polyacrylamide-based hydrogels functionalized with azobenzene (guest) or cyclodextrin (host) moieties. Reversible adhesion and dissociation of the host gel from the guest gel may be controlled by photoirradiation. The differential affinities of α-cyclodextrin or β-cyclodextrin for the trans-azobenzene and cis-azobenzene are employed in the construction of a photoswitchable gel assembly system.