Research press release


Nature Communications

Epidemiology: Planning a HIV intervention rollout



今回、Sally Blowerたちは、地理空間的モデリングを用い、平等主義と功利主義のいずれの原則を採用すれば最も効果的な導入計画になるのかを調査した。功利主義の原則に従った計画は、社会的利益の最大化に重点的に取り組むが、平等主義の原則に従った計画は、資源の利用機会の平等を最優先する。それぞれの計画で使用される資源の量は同じとした。


Approximately 40% more HIV infections could be prevented in Sub-Saharan Africa in the first year of a pre-exposure intervention rollout, by prioritising areas of high incidence, as opposed to focussing on equity of access to resources, reports a study in Nature Communications.

Approximately 34 million people worldwide are infected with HIV, with 3 million new infections per year in Sub-Saharan Africa alone. Pre-exposure HIV interventions, using anti-retroviral therapies, may soon be rolled out in Sub-Saharan African countries in an attempt to slow the rate of infection; however, resources are limited. The WHO recommends a number of different ethical principles to consider when deciding how to allocate scarce resources, including egalitarian and utilitarian principles.

Sally Blower and colleagues use geospatial modelling to determine which of these two principles makes for the most effective rollout plan. A plan according to utilitarian principles focuses on maximising societal benefits, while a plan following egalitarian principles prioritises equity of access to resources. Both plans use the same amount of resources.

The authors find that the efficacy of interventions increases disproportionately with increasing incidence of HIV in a given area and that focussing on these areas, as per the utilitarian plan, may lead to a 40% increase in prevented cases in the first year. The study is limited to geographic modelling and does not address the more complex problem of how to allocate resources between different HIV prevention methods.

doi: 10.1038/ncomms6454

「Nature 関連誌注目のハイライト」は、ネイチャー広報部門が報道関係者向けに作成したリリースを翻訳したものです。より正確かつ詳細な情報が必要な場合には、必ず原著論文をご覧ください。

メールマガジンリストの「Nature 関連誌今週のハイライト」にチェックをいれていただきますと、毎週最新のNature 関連誌のハイライトを皆様にお届けいたします。