Research press release


Nature Communications

Psychology: Treating geriatric depression with computerised therapy



今回、Sarah Shizuko Morimotoたちは、コンピューター化された認知機能訓練プログラムを作成し、これを使って、治療抵抗性を示す11人の高齢者(60~89歳)のトレーニングを行い、学習と記憶の諸側面の改善を試みた。その結果、この訓練プログラムは、従来の抗うつ剤で症状が改善しなかった患者において、代表的な治療薬であるエスシタロプラムと同等な症状改善効果のあることが明らかになった。


The symptoms of some sufferers of treatment-resistant geriatric depression can be alleviated with specially designed computer games, reports a study in Nature Communications this week. These findings indicate that some forms of behavioural therapy may provide realistic measures for treating clinical depression.

Clinical depression affects a large number of older adults and while psychotherapy and drugs are effective measures in some individuals, many are resistant to these treatments. For these individuals, there is currently an unmet need for more effective treatments.

Sarah Shizuko Morimoto and colleagues created computerised cognitive training programs to train 11 older, treatment-resistant adults (60 to 89 years old), to improve aspects of learning and memory. They find the computerised cognitive training programs improve symptoms to the same degree as the gold standard drug treatment, escitalopram, in patients who failed to show improvement with conventional antidepressants.

While researchers indicate that a full clinical study would be needed to confirm these findings, they hope that this study will promote more research into alternative therapies for clinical depression.

doi: 10.1038/ncomms5579

「Nature 関連誌注目のハイライト」は、ネイチャー広報部門が報道関係者向けに作成したリリースを翻訳したものです。より正確かつ詳細な情報が必要な場合には、必ず原著論文をご覧ください。

メールマガジンリストの「Nature 関連誌今週のハイライト」にチェックをいれていただきますと、毎週最新のNature 関連誌のハイライトを皆様にお届けいたします。