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News

Genentech discloses safety concerns over Avastin

doi: 10.1038/nbt1004-1198

Electoral campaign delays resolution of biotech issues

doi: 10.1038/nbt1019

Inhaled insulin products puff along

doi: 10.1038/nbt1004-1195

Growing pains in AIDS drug development

doi: 10.1038/nbt1004-1194

Features

複雑さは商品になるか

Can complexity be commercialized?

doi: 10.1038/nbt1004-1223

EUの遺伝子検査サービスの品質保証と協調

Towards quality assurance and harmonization of genetic testing services in the European Union

doi: 10.1038/nbt1004-1230

News & Views

タンパク質の梯子を上る

Climbing the protein ladder

doi: 10.1038/nbt1004-1242

心音を刻む胚性幹細胞

Embryonic stem cells pace the heart

doi: 10.1038/nbt1004-1237

ヨウ素を構造解析に利用する

Phasing in iodine for structure determination

doi: 10.1038/nbt1004-1239

新アルゴリズムTANGO

A universal TANGO?

doi: 10.1038/nbt1004-1240

魔法の弾丸が狙う甘い標的を作る

Engineering sweet targets for magic bullets

doi: 10.1038/nbt1004-1244

Patents

遺伝子関連発明の特許保護に必要な開示の程度

The level of disclosure necessary for patent protection of genetic innovations

doi: 10.1038/nbt1004-1307

Letters

ペプチドおよびタンパク質の凝集が受ける配列依存効果および変異効果の予測

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins

doi: 10.1038/nbt1012

p-ヨード-L-フェニルアラニンの部位特異的導入によるタンパク質の構造解析

The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination

doi: 10.1038/nbt1013

タンパク質の部分加水分解で生じるポリペプチドラダーの質量分析によるタンパク質配列決定法

Protein sequencing by mass analysis of polypeptide ladders after controlled protein hydrolysis

doi: 10.1038/nbt1011

Computational Biology

What is a hidden Markov model?

doi: 10.1038/nbt1004-1315

Ten thousand interactions for the molecular biologist

doi: 10.1038/nbt1018

Naturejobs

Changing talent needs to realize biotech products

doi: 10.1038/nbt1004-1327

Opinion and Comment

Putting Cartagena into practice

doi: 10.1038/nbt1004-1207b

Data hoarding is harming proteomics

doi: 10.1038/nbt1004-1209a

A partnership between biology and engineering

doi: 10.1038/nbt1004-1211

The need for international stem cell agreements

doi: 10.1038/nbt1004-1207a

The impact of systems approaches on biological problems in drug discovery

doi: 10.1038/nbt1004-1215

Reply to ',Data hoarding is harming proteomics',

doi: 10.1038/nbt1004-1209b

Reviews

分子生物学からシステム生物学への進化

The evolution of molecular biology into systems biology p.1249

doi: 10.1038/nbt1020

システム生物学による系統改良への生物学的複雑性の利用

Exploiting biological complexity for strain improvement through systems biology p.1261

doi: 10.1038/nbt1016

Review Summary

哺乳類の生物複雑性のモデル化という問題

The challenges of modeling mammalian biocomplexity

doi: 10.1038/nbt1015

Articles

好二酸化炭素性ルーメン細菌Mannheimia succiniciproducensのゲノム配列

The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens

doi: 10.1038/nbt1010

ヒト胚性幹細胞に由来する心筋細胞の電気機械的統合

Electromechanical integration of cardiomyocytes derived from human embryonic stem cells

doi: 10.1038/nbt1014

Resources

Expression systems and Imaging & microscopy

doi: 10.1038/nbt1004-1313

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