Volume 499 Number 7456

今週のハイライト

目次

    array:6 [
      14 => NPG_Content_Model_Record_JournalSection {#13825
        #_mapperClass: "NPG_Content_Model_Mapper_JournalSection"
        #_formClass: "NPG_Content_Form_JournalSection"
        #_journal: NPG_Content_Model_Record_Journal {#13839
          #_mapperClass: "NPG_Content_Model_Mapper_Journal"
          #_formClass: "NPG_Content_Form_Journal"
          #_name: null
          #_shortname: null
          #_frequence: null
          #_openAccess: null
          #_launchDate: null
          #_type: null
          #_category: null
          #_paywall: null
          #_adddate: null
          #_moddate: null
          #_lastEditedBy: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_Content_Form_Journal {#13840
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "adddate" => Zend_Form_Element_Hidden {#13843 …30}
              "moddate" => Zend_Form_Element_Hidden {#13847 …30}
              "last_edited_by" => Zend_Form_Element_Hidden {#13851 …30}
              "name" => Zend_Form_Element_Text {#13855 …30}
              "shortname" => Zend_Form_Element_Text {#13859 …30}
              "frequence" => NPG_Form_Element_JournalFrequence {#13863 …35}
              "open_access" => Zend_Form_Element_Checkbox {#13867 …34}
              "paywall" => Zend_Form_Element_Checkbox {#13871 …34}
              "launch_date" => Zend_Form_Element_Text {#13875 …30}
              "type" => NPG_Form_Element_JournalType {#13879 …35}
              "category" => NPG_Form_Element_JournalCategory {#13883 …35}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#13841 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#13842 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "adddate" => null
              "moddate" => null
              "last_edited_by" => null
              "name" => null
              "shortname" => null
              "frequence" => null
              "open_access" => null
              "paywall" => null
              "launch_date" => null
              "type" => null
              "category" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 14
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_name: "Editorial"
        #_pluralName: "Editorials"
        #_shortname: "ed"
        #_identifier: "ed"
        #_tocOrder: 2
        #_presentInToc: true
        #_exportable: false
        #_adddate: Zend_Date {#13934
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1343791229"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_moddate: Zend_Date {#13935
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1358702216"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_lastEditedBy: NPG_System_Model_Record_User {#13837
          #_mapperClass: "NPG_System_Model_Mapper_User"
          #_formClass: "NPG_System_Form_User"
          #_email: null
          #_firstname: null
          #_lastname: null
          #_password: null
          #_lastLogin: null
          #_lastFailedLogin: null
          #_nFailedLogin: 0
          #_banned: null
          #_deleted: null
          #_adddate: null
          #_moddate: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_System_Form_User {#13838
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "email" => Zend_Form_Element_Text {#13988 …30}
              "firstname" => Zend_Form_Element_Text {#13992 …30}
              "lastname" => Zend_Form_Element_Text {#13996 …30}
              "password" => Zend_Form_Element_Password {#14000 …31}
              "last_login" => Zend_Form_Element_Text {#14005 …30}
              "last_failed_login" => Zend_Form_Element_Text {#14010 …30}
              "n_failed_login" => Zend_Form_Element_Hidden {#14014 …30}
              "banned" => Zend_Form_Element_Checkbox {#14018 …34}
              "deleted" => Zend_Form_Element_Checkbox {#14022 …34}
              "adddate" => Zend_Form_Element_Text {#14026 …30}
              "moddate" => Zend_Form_Element_Text {#14030 …30}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#13986 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#13987 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "email" => null
              "firstname" => null
              "lastname" => null
              "password" => null
              "last_login" => null
              "last_failed_login" => null
              "n_failed_login" => null
              "banned" => null
              "deleted" => null
              "adddate" => null
              "moddate" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 1
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_dirty: true
        #_lazyLoaded: false
        #_form: NPG_Content_Form_JournalSection {#13887
          #_attribs: []
          #_decorators: array:3 [
            "FormElements" => array:2 [
              "decorator" => "FormElements"
              "options" => null
            ]
            "HtmlTag" => array:2 [
              "decorator" => "HtmlTag"
              "options" => array:2 [ …2]
            ]
            "Form" => array:2 [
              "decorator" => "Form"
              "options" => null
            ]
          ]
          #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
          #_description: null
          #_disableLoadDefaultDecorators: false
          #_displayGroupPrefixPaths: []
          #_displayGroups: []
          #_elementDecorators: array:1 [
            0 => "Composite"
          ]
          #_elementPrefixPaths: array:2 [
            0 => array:3 [
              "prefix" => "NPG_Validate"
              "path" => "NPG/Validate/"
              "type" => "validate"
            ]
            1 => array:3 [
              "prefix" => "NPG_Filter"
              "path" => "NPG/Filter/"
              "type" => "filter"
            ]
          ]
          #_elements: array:11 [
            "adddate" => Zend_Form_Element_Hidden {#13890
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "adddate"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "moddate" => Zend_Form_Element_Hidden {#13894
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "moddate"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "last_edited_by" => Zend_Form_Element_Hidden {#13898
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "last_edited_by"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "journal_id" => Zend_Form_Element_Hidden {#13902
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "journal_id"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "name" => Zend_Form_Element_Text {#13906
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "name"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "plural_name" => Zend_Form_Element_Text {#13910
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Plural name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "plural_name"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "shortname" => Zend_Form_Element_Text {#13914
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Shortname"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "shortname"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "identifier" => Zend_Form_Element_Text {#13918
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Identifier"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "identifier"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "toc_order" => Zend_Form_Element_Text {#13922
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "TOC order"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "toc_order"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "present_in_toc" => Zend_Form_Element_Checkbox {#13926
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Present in TOC"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "present_in_toc"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "exportable" => Zend_Form_Element_Checkbox {#13930
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Exportable"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "exportable"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
          ]
          #_elementsBelongTo: null
          #_errorMessages: []
          #_errorsExist: false
          #_errorsForced: false
          #_formOrder: null
          #_isArray: false
          #_legend: null
          #_loaders: array:2 [
            "ELEMENT" => Zend_Loader_PluginLoader {#13888
              #_loadedPluginPaths: []
              #_loadedPlugins: array:3 [ …3]
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
            "DECORATOR" => Zend_Loader_PluginLoader {#13889
              #_loadedPluginPaths: []
              #_loadedPlugins: []
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
          ]
          #_methods: array:4 [
            0 => "delete"
            1 => "get"
            2 => "post"
            3 => "put"
          ]
          #_order: array:11 [
            "adddate" => null
            "moddate" => null
            "last_edited_by" => null
            "journal_id" => null
            "name" => null
            "plural_name" => null
            "shortname" => null
            "identifier" => null
            "toc_order" => null
            "present_in_toc" => null
            "exportable" => null
          ]
          #_orderUpdated: true
          #_subFormPrefixPaths: []
          #_subForms: []
          #_translator: null
          #_translatorDisabled: false
          #_view: null
          #_isRendered: false
        }
        #_mapper: null
        #_id: 14
        #_persisted: true
        #_validate: false
        #_foreignKeys: array:2 [
          "journal_id" => "14"
          "last_edited_by" => "1"
        ]
      }
      24 => NPG_Content_Model_Record_JournalSection {#13936
        #_mapperClass: "NPG_Content_Model_Mapper_JournalSection"
        #_formClass: "NPG_Content_Form_JournalSection"
        #_journal: NPG_Content_Model_Record_Journal {#13938
          #_mapperClass: "NPG_Content_Model_Mapper_Journal"
          #_formClass: "NPG_Content_Form_Journal"
          #_name: null
          #_shortname: null
          #_frequence: null
          #_openAccess: null
          #_launchDate: null
          #_type: null
          #_category: null
          #_paywall: null
          #_adddate: null
          #_moddate: null
          #_lastEditedBy: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_Content_Form_Journal {#13982
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "adddate" => Zend_Form_Element_Hidden {#13983 …30}
              "moddate" => Zend_Form_Element_Hidden {#13979 …30}
              "last_edited_by" => Zend_Form_Element_Hidden {#13975 …30}
              "name" => Zend_Form_Element_Text {#13971 …30}
              "shortname" => Zend_Form_Element_Text {#13967 …30}
              "frequence" => NPG_Form_Element_JournalFrequence {#13964 …35}
              "open_access" => Zend_Form_Element_Checkbox {#13960 …34}
              "paywall" => Zend_Form_Element_Checkbox {#13955 …34}
              "launch_date" => Zend_Form_Element_Text {#13951 …30}
              "type" => NPG_Form_Element_JournalType {#13947 …35}
              "category" => NPG_Form_Element_JournalCategory {#13943 …35}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#13985 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#13984 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "adddate" => null
              "moddate" => null
              "last_edited_by" => null
              "name" => null
              "shortname" => null
              "frequence" => null
              "open_access" => null
              "paywall" => null
              "launch_date" => null
              "type" => null
              "category" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 14
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_name: "News"
        #_pluralName: "News"
        #_shortname: "nw"
        #_identifier: "nw"
        #_tocOrder: 10
        #_presentInToc: true
        #_exportable: true
        #_adddate: Zend_Date {#14082
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1343791229"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_moddate: Zend_Date {#14083
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1381783004"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_lastEditedBy: NPG_System_Model_Record_User {#13937
          #_mapperClass: "NPG_System_Model_Mapper_User"
          #_formClass: "NPG_System_Form_User"
          #_email: null
          #_firstname: null
          #_lastname: null
          #_password: null
          #_lastLogin: null
          #_lastFailedLogin: null
          #_nFailedLogin: 0
          #_banned: null
          #_deleted: null
          #_adddate: null
          #_moddate: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_System_Form_User {#13939
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "email" => Zend_Form_Element_Text {#14136 …30}
              "firstname" => Zend_Form_Element_Text {#14140 …30}
              "lastname" => Zend_Form_Element_Text {#14144 …30}
              "password" => Zend_Form_Element_Password {#14148 …31}
              "last_login" => Zend_Form_Element_Text {#14153 …30}
              "last_failed_login" => Zend_Form_Element_Text {#14158 …30}
              "n_failed_login" => Zend_Form_Element_Hidden {#14162 …30}
              "banned" => Zend_Form_Element_Checkbox {#14166 …34}
              "deleted" => Zend_Form_Element_Checkbox {#14170 …34}
              "adddate" => Zend_Form_Element_Text {#14174 …30}
              "moddate" => Zend_Form_Element_Text {#14178 …30}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#14134 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#14135 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "email" => null
              "firstname" => null
              "lastname" => null
              "password" => null
              "last_login" => null
              "last_failed_login" => null
              "n_failed_login" => null
              "banned" => null
              "deleted" => null
              "adddate" => null
              "moddate" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 1
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_dirty: true
        #_lazyLoaded: false
        #_form: NPG_Content_Form_JournalSection {#14035
          #_attribs: []
          #_decorators: array:3 [
            "FormElements" => array:2 [
              "decorator" => "FormElements"
              "options" => null
            ]
            "HtmlTag" => array:2 [
              "decorator" => "HtmlTag"
              "options" => array:2 [ …2]
            ]
            "Form" => array:2 [
              "decorator" => "Form"
              "options" => null
            ]
          ]
          #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
          #_description: null
          #_disableLoadDefaultDecorators: false
          #_displayGroupPrefixPaths: []
          #_displayGroups: []
          #_elementDecorators: array:1 [
            0 => "Composite"
          ]
          #_elementPrefixPaths: array:2 [
            0 => array:3 [
              "prefix" => "NPG_Validate"
              "path" => "NPG/Validate/"
              "type" => "validate"
            ]
            1 => array:3 [
              "prefix" => "NPG_Filter"
              "path" => "NPG/Filter/"
              "type" => "filter"
            ]
          ]
          #_elements: array:11 [
            "adddate" => Zend_Form_Element_Hidden {#14038
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "adddate"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "moddate" => Zend_Form_Element_Hidden {#14042
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "moddate"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "last_edited_by" => Zend_Form_Element_Hidden {#14046
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "last_edited_by"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "journal_id" => Zend_Form_Element_Hidden {#14050
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "journal_id"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "name" => Zend_Form_Element_Text {#14054
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "name"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "plural_name" => Zend_Form_Element_Text {#14058
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Plural name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "plural_name"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "shortname" => Zend_Form_Element_Text {#14062
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Shortname"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "shortname"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "identifier" => Zend_Form_Element_Text {#14066
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Identifier"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "identifier"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "toc_order" => Zend_Form_Element_Text {#14070
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "TOC order"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "toc_order"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "present_in_toc" => Zend_Form_Element_Checkbox {#14074
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Present in TOC"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "present_in_toc"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "exportable" => Zend_Form_Element_Checkbox {#14078
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Exportable"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "exportable"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
          ]
          #_elementsBelongTo: null
          #_errorMessages: []
          #_errorsExist: false
          #_errorsForced: false
          #_formOrder: null
          #_isArray: false
          #_legend: null
          #_loaders: array:2 [
            "ELEMENT" => Zend_Loader_PluginLoader {#14036
              #_loadedPluginPaths: []
              #_loadedPlugins: array:3 [ …3]
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
            "DECORATOR" => Zend_Loader_PluginLoader {#14037
              #_loadedPluginPaths: []
              #_loadedPlugins: []
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
          ]
          #_methods: array:4 [
            0 => "delete"
            1 => "get"
            2 => "post"
            3 => "put"
          ]
          #_order: array:11 [
            "adddate" => null
            "moddate" => null
            "last_edited_by" => null
            "journal_id" => null
            "name" => null
            "plural_name" => null
            "shortname" => null
            "identifier" => null
            "toc_order" => null
            "present_in_toc" => null
            "exportable" => null
          ]
          #_orderUpdated: true
          #_subFormPrefixPaths: []
          #_subForms: []
          #_translator: null
          #_translatorDisabled: false
          #_view: null
          #_isRendered: false
        }
        #_mapper: null
        #_id: 24
        #_persisted: true
        #_validate: false
        #_foreignKeys: array:2 [
          "journal_id" => "14"
          "last_edited_by" => "1"
        ]
      }
      30 => NPG_Content_Model_Record_JournalSection {#14084
        #_mapperClass: "NPG_Content_Model_Mapper_JournalSection"
        #_formClass: "NPG_Content_Form_JournalSection"
        #_journal: NPG_Content_Model_Record_Journal {#14086
          #_mapperClass: "NPG_Content_Model_Mapper_Journal"
          #_formClass: "NPG_Content_Form_Journal"
          #_name: null
          #_shortname: null
          #_frequence: null
          #_openAccess: null
          #_launchDate: null
          #_type: null
          #_category: null
          #_paywall: null
          #_adddate: null
          #_moddate: null
          #_lastEditedBy: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_Content_Form_Journal {#14130
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "adddate" => Zend_Form_Element_Hidden {#14131 …30}
              "moddate" => Zend_Form_Element_Hidden {#14127 …30}
              "last_edited_by" => Zend_Form_Element_Hidden {#14123 …30}
              "name" => Zend_Form_Element_Text {#14119 …30}
              "shortname" => Zend_Form_Element_Text {#14115 …30}
              "frequence" => NPG_Form_Element_JournalFrequence {#14112 …35}
              "open_access" => Zend_Form_Element_Checkbox {#14108 …34}
              "paywall" => Zend_Form_Element_Checkbox {#14103 …34}
              "launch_date" => Zend_Form_Element_Text {#14099 …30}
              "type" => NPG_Form_Element_JournalType {#14095 …35}
              "category" => NPG_Form_Element_JournalCategory {#14091 …35}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#14133 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#14132 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "adddate" => null
              "moddate" => null
              "last_edited_by" => null
              "name" => null
              "shortname" => null
              "frequence" => null
              "open_access" => null
              "paywall" => null
              "launch_date" => null
              "type" => null
              "category" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 14
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_name: "News Features"
        #_pluralName: "News Features"
        #_shortname: "nf"
        #_identifier: "nf"
        #_tocOrder: 20
        #_presentInToc: true
        #_exportable: true
        #_adddate: Zend_Date {#14230
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1343791230"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_moddate: Zend_Date {#14231
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1344461350"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_lastEditedBy: NPG_System_Model_Record_User {#14085
          #_mapperClass: "NPG_System_Model_Mapper_User"
          #_formClass: "NPG_System_Form_User"
          #_email: null
          #_firstname: null
          #_lastname: null
          #_password: null
          #_lastLogin: null
          #_lastFailedLogin: null
          #_nFailedLogin: 0
          #_banned: null
          #_deleted: null
          #_adddate: null
          #_moddate: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_System_Form_User {#14087
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "email" => Zend_Form_Element_Text {#14284 …30}
              "firstname" => Zend_Form_Element_Text {#14288 …30}
              "lastname" => Zend_Form_Element_Text {#14292 …30}
              "password" => Zend_Form_Element_Password {#14296 …31}
              "last_login" => Zend_Form_Element_Text {#14301 …30}
              "last_failed_login" => Zend_Form_Element_Text {#14306 …30}
              "n_failed_login" => Zend_Form_Element_Hidden {#14310 …30}
              "banned" => Zend_Form_Element_Checkbox {#14314 …34}
              "deleted" => Zend_Form_Element_Checkbox {#14318 …34}
              "adddate" => Zend_Form_Element_Text {#14322 …30}
              "moddate" => Zend_Form_Element_Text {#14326 …30}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#14282 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#14283 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "email" => null
              "firstname" => null
              "lastname" => null
              "password" => null
              "last_login" => null
              "last_failed_login" => null
              "n_failed_login" => null
              "banned" => null
              "deleted" => null
              "adddate" => null
              "moddate" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 1
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_dirty: true
        #_lazyLoaded: false
        #_form: NPG_Content_Form_JournalSection {#14183
          #_attribs: []
          #_decorators: array:3 [
            "FormElements" => array:2 [
              "decorator" => "FormElements"
              "options" => null
            ]
            "HtmlTag" => array:2 [
              "decorator" => "HtmlTag"
              "options" => array:2 [ …2]
            ]
            "Form" => array:2 [
              "decorator" => "Form"
              "options" => null
            ]
          ]
          #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
          #_description: null
          #_disableLoadDefaultDecorators: false
          #_displayGroupPrefixPaths: []
          #_displayGroups: []
          #_elementDecorators: array:1 [
            0 => "Composite"
          ]
          #_elementPrefixPaths: array:2 [
            0 => array:3 [
              "prefix" => "NPG_Validate"
              "path" => "NPG/Validate/"
              "type" => "validate"
            ]
            1 => array:3 [
              "prefix" => "NPG_Filter"
              "path" => "NPG/Filter/"
              "type" => "filter"
            ]
          ]
          #_elements: array:11 [
            "adddate" => Zend_Form_Element_Hidden {#14186
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "adddate"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "moddate" => Zend_Form_Element_Hidden {#14190
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "moddate"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "last_edited_by" => Zend_Form_Element_Hidden {#14194
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "last_edited_by"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "journal_id" => Zend_Form_Element_Hidden {#14198
              +helper: "formHidden"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: null
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "journal_id"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "name" => Zend_Form_Element_Text {#14202
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "name"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "plural_name" => Zend_Form_Element_Text {#14206
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Plural name"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "plural_name"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:2 [ …2]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "shortname" => Zend_Form_Element_Text {#14210
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Shortname"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "shortname"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "identifier" => Zend_Form_Element_Text {#14214
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Identifier"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "identifier"
              #_order: null
              #_required: false
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "toc_order" => Zend_Form_Element_Text {#14218
              +helper: "formText"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: array:1 [ …1]
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "TOC order"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "toc_order"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_value: null
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "present_in_toc" => Zend_Form_Element_Checkbox {#14222
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:1 [ …1]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Present in TOC"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "present_in_toc"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
            "exportable" => Zend_Form_Element_Checkbox {#14226
              +checked: false
              +helper: "formCheckbox"
              +options: array:2 [ …2]
              #_checkedValue: "1"
              #_uncheckedValue: "0"
              #_value: "0"
              #_allowEmpty: true
              #_autoInsertNotEmptyValidator: true
              #_belongsTo: null
              #_decorators: array:2 [ …2]
              #_description: null
              #_disableLoadDefaultDecorators: false
              #_errorMessages: []
              #_errors: []
              #_errorMessageSeparator: "; "
              #_filters: []
              #_ignore: false
              #_isArray: false
              #_isError: false
              #_isErrorForced: false
              #_label: "Exportable"
              #_loaders: array:3 [ …3]
              #_messages: []
              #_name: "exportable"
              #_order: null
              #_required: true
              #_translator: null
              #_translatorDisabled: false
              #_type: null
              #_validators: array:1 [ …1]
              #_validatorRules: []
              #_view: null
              #_isPartialRendering: false
              #_concatJustValuesInErrorMessage: false
            }
          ]
          #_elementsBelongTo: null
          #_errorMessages: []
          #_errorsExist: false
          #_errorsForced: false
          #_formOrder: null
          #_isArray: false
          #_legend: null
          #_loaders: array:2 [
            "ELEMENT" => Zend_Loader_PluginLoader {#14184
              #_loadedPluginPaths: []
              #_loadedPlugins: array:3 [ …3]
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
            "DECORATOR" => Zend_Loader_PluginLoader {#14185
              #_loadedPluginPaths: []
              #_loadedPlugins: []
              #_prefixToPaths: array:2 [ …2]
              #_useStaticRegistry: null
            }
          ]
          #_methods: array:4 [
            0 => "delete"
            1 => "get"
            2 => "post"
            3 => "put"
          ]
          #_order: array:11 [
            "adddate" => null
            "moddate" => null
            "last_edited_by" => null
            "journal_id" => null
            "name" => null
            "plural_name" => null
            "shortname" => null
            "identifier" => null
            "toc_order" => null
            "present_in_toc" => null
            "exportable" => null
          ]
          #_orderUpdated: true
          #_subFormPrefixPaths: []
          #_subForms: []
          #_translator: null
          #_translatorDisabled: false
          #_view: null
          #_isRendered: false
        }
        #_mapper: null
        #_id: 30
        #_persisted: true
        #_validate: false
        #_foreignKeys: array:2 [
          "journal_id" => "14"
          "last_edited_by" => "1"
        ]
      }
      27 => NPG_Content_Model_Record_JournalSection {#14232
        #_mapperClass: "NPG_Content_Model_Mapper_JournalSection"
        #_formClass: "NPG_Content_Form_JournalSection"
        #_journal: NPG_Content_Model_Record_Journal {#14234
          #_mapperClass: "NPG_Content_Model_Mapper_Journal"
          #_formClass: "NPG_Content_Form_Journal"
          #_name: null
          #_shortname: null
          #_frequence: null
          #_openAccess: null
          #_launchDate: null
          #_type: null
          #_category: null
          #_paywall: null
          #_adddate: null
          #_moddate: null
          #_lastEditedBy: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_Content_Form_Journal {#14278
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "adddate" => Zend_Form_Element_Hidden {#14279 …30}
              "moddate" => Zend_Form_Element_Hidden {#14275 …30}
              "last_edited_by" => Zend_Form_Element_Hidden {#14271 …30}
              "name" => Zend_Form_Element_Text {#14267 …30}
              "shortname" => Zend_Form_Element_Text {#14263 …30}
              "frequence" => NPG_Form_Element_JournalFrequence {#14260 …35}
              "open_access" => Zend_Form_Element_Checkbox {#14256 …34}
              "paywall" => Zend_Form_Element_Checkbox {#14251 …34}
              "launch_date" => Zend_Form_Element_Text {#14247 …30}
              "type" => NPG_Form_Element_JournalType {#14243 …35}
              "category" => NPG_Form_Element_JournalCategory {#14239 …35}
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [
              "ELEMENT" => Zend_Loader_PluginLoader {#14281 …4}
              "DECORATOR" => Zend_Loader_PluginLoader {#14280 …4}
            ]
            #_methods: array:4 [
              0 => "delete"
              1 => "get"
              2 => "post"
              3 => "put"
            ]
            #_order: array:11 [
              "adddate" => null
              "moddate" => null
              "last_edited_by" => null
              "name" => null
              "shortname" => null
              "frequence" => null
              "open_access" => null
              "paywall" => null
              "launch_date" => null
              "type" => null
              "category" => null
            ]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 14
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_name: "News & Views"
        #_pluralName: "News & Views"
        #_shortname: "nv"
        #_identifier: "nv"
        #_tocOrder: 30
        #_presentInToc: true
        #_exportable: true
        #_adddate: Zend_Date {#14378
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1343791230"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_moddate: Zend_Date {#14379
          -_locale: "en_US"
          -_fractional: 0
          -_precision: 3
          -_unixTimestamp: "1344460508"
          -_timezone: "Asia/Tokyo"
          -_offset: -32400
          -_syncronised: 0
          #_dst: true
        }
        #_lastEditedBy: NPG_System_Model_Record_User {#14233
          #_mapperClass: "NPG_System_Model_Mapper_User"
          #_formClass: "NPG_System_Form_User"
          #_email: null
          #_firstname: null
          #_lastname: null
          #_password: null
          #_lastLogin: null
          #_lastFailedLogin: null
          #_nFailedLogin: 0
          #_banned: null
          #_deleted: null
          #_adddate: null
          #_moddate: null
          #_dirty: false
          #_lazyLoaded: true
          #_form: NPG_System_Form_User {#14235
            #_attribs: []
            #_decorators: array:3 [
              "FormElements" => array:2 [ …2]
              "HtmlTag" => array:2 [ …2]
              "Form" => array:2 [ …2]
            ]
            #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
            #_description: null
            #_disableLoadDefaultDecorators: false
            #_displayGroupPrefixPaths: []
            #_displayGroups: []
            #_elementDecorators: array:1 [
              0 => "Composite"
            ]
            #_elementPrefixPaths: array:2 [
              0 => array:3 [ …3]
              1 => array:3 [ …3]
            ]
            #_elements: array:11 [
              "email" => Zend_Form_Element_Text {#14432 …30}
              "firstname" => Zend_Form_Element_Text {#14436 …30}
              "lastname" => Zend_Form_Element_Text {#14440 …30}
              "password" => Zend_Form_Element_Password {#14444 …31}
              "last_login" => Zend_Form_Element_Text {#14449 …30}
              "last_failed_login" => Zend_Form_Element_Text {#14454 …30}
               …5
            ]
            #_elementsBelongTo: null
            #_errorMessages: []
            #_errorsExist: false
            #_errorsForced: false
            #_formOrder: null
            #_isArray: false
            #_legend: null
            #_loaders: array:2 [ …2]
            #_methods: array:4 [ …4]
            #_order: array:11 [ …11]
            #_orderUpdated: true
            #_subFormPrefixPaths: []
            #_subForms: []
            #_translator: null
            #_translatorDisabled: false
            #_view: null
            #_isRendered: false
          }
          #_mapper: null
          #_id: 1
          #_persisted: true
          #_validate: true
          #_foreignKeys: []
        }
        #_dirty: true
        #_lazyLoaded: false
        #_form: NPG_Content_Form_JournalSection {#14331
          #_attribs: []
          #_decorators: array:3 [
            "FormElements" => array:2 [ …2]
            "HtmlTag" => array:2 [ …2]
            "Form" => array:2 [ …2]
          ]
          #_defaultDisplayGroupClass: "Zend_Form_DisplayGroup"
          #_description: null
          #_disableLoadDefaultDecorators: false
          #_displayGroupPrefixPaths: []
          #_displayGroups: []
          #_elementDecorators: array:1 [
            0 => "Composite"
          ]
          #_elementPrefixPaths: array:2 [
            0 => array:3 [ …3]
            1 => array:3 [ …3]
          ]
          #_elements: array:11 [
            "adddate" => Zend_Form_Element_Hidden {#14334 …30}
            "moddate" => Zend_Form_Element_Hidden {#14338 …30}
            "last_edited_by" => Zend_Form_Element_Hidden {#14342 …30}
            "journal_id" => Zend_Form_Element_Hidden {#14346 …30}
            "name" => Zend_Form_Element_Text {#14350 …30}
            "plural_name" => Zend_Form_Element_Text {#14354 …30}
            "shortname" => Zend_Form_Element_Text {#14358 …30}
            "identifier" => Zend_Form_Element_Text {#14362 …30}
            "toc_order" => Zend_Form_Element_Text {#14366 …30}
            "present_in_toc" => Zend_Form_Element_Checkbox {#14370 …34}
            "exportable" => Zend_Form_Element_Checkbox {#14374 …34}
          ]
          #_elementsBelongTo: null
          #_errorMessages: []
          #_errorsExist: false
          #_errorsForced: false
          #_formOrder: null
          #_isArray: false
          #_legend: null
          #_loaders: array:2 [
            "ELEMENT" => Zend_Loader_PluginLoader {#14332 …4}
            "DECORATOR" => Zend_Loader_PluginLoader {#14333 …4}
          ]
          #_methods: array:4 [
            0 => "delete"
            1 => "get"
            2 => "post"
            3 => "put"
          ]
          #_order: array:11 [
            "adddate" => null
            "moddate" => null
            "last_edited_by" => null
            "journal_id" => null
            "name" => null
            "plural_name" => null
            "shortname" => null
            "identifier" => null
            "toc_order" => null
            "present_in_toc" => null
            "exportable" => null
          ]
          #_orderUpdated: true
          #_subFormPrefixPaths: []
          #_subForms: []
          #_translator: null
          #_translatorDisabled: false
          #_view: null
          #_isRendered: false
        }
        #_mapper: null
        #_id: 27
        #_persisted: true
        #_validate: false
        #_foreignKeys: array:2 [
          "journal_id" => "14"
          "last_edited_by" => "1"
        ]
      }
      2 => NPG_Content_Model_Record_JournalSection {#14380
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Editorials

米オバマ大統領は、地球温暖化問題についての立派な発言を実行に移し、石炭発電や燃料効率の規制に乗り出すべきだ。

More than hot air p.5

US President Barack Obama gave a fine speech on global warming, but now he must deliver on regulations for coal power and greater fuel economy.

doi: 10.1038/499005a

ロシア科学アカデミーの改革を成功させるには、専門家からの助言や協議が不可欠だ。

Russian roulette p.5

Reforms without consultation will destroy the Russian Academy of Sciences.

doi: 10.1038/499005b

移植や研究用の組織提供を促進するためには、「推定同意」を含め、さまざまな取り組みが必要だ。

Presumed consent p.6

More must be done to boost tissue donation for transplantation and research.

doi: 10.1038/499006a

News

EUが、バイオ燃料政策を180度転換する方向へ。

EU debates U-turn on biofuels policy p.13

Key vote could signal withdrawal of support from biodiesel.

doi: 10.1038/499013a

中国が、地下水の汚染浄化に巨額の予算を。

China gears up to tackle tainted water p.14

Government is set to spend 500 million renminbi to clean up groundwater polluted by industry and agriculture.

doi: 10.1038/499015a

米国で新しい科学教育指針が作成され、それを取り入れた州では気候変動学と進化学を高校より前に教えることに。

Evolution makes the grade p.15

Kansas, Kentucky and other states will also teach climate-change science.

doi: 10.1038/499014a

生物工学分野でも、特許重視だった企業にオープンアクセス推進の動きが。

Bioengineers look beyond patents p.16

Synthetic-biology company pushes open-source models.

doi: 10.1038/499016a

米上院で移民制度改革法が可決され、外国人科学者の永住ビザ取得が容易に。

US Senate backs immigration plan p.17

Proposal would lift visa caps for US-trained scientists and engineers.

doi: 10.1038/499017a

EUが、次期研究助成計画「ホライズン2020」の間接費の取り扱いで、ようやく合意へ。

European deal cuts red tape p.18

Horizon 2020 research programme streamlines project reimbursements.

doi: 10.1038/499018a

News Features

組織工学:心臓の作り方

Tissue engineering: How to build a heart p.20

心臓移植を必要とする何万人もの患者の願いに応えようと、移植用心臓の作製の研究が盛んに行われている。

doi: 10.1038/499020a

News & Views

社会科学:子育てのコスト

Social science: The cost of children p.32

生まれる子供の数が減少していることの原因について調査が行われ、経済的な動機は、子供の死亡率あるいは社会的学習よりも影響力が大きいだけでなく、これらの要因間の関係を増強していることがわかった。

doi: 10.1038/nature12257

惑星科学:惑星形成はロバストな過程である

Planetary science: The robustness of planet formation p.33

散開星団中にある2つの惑星の観測から、惑星系は散開星団の形成直後のまだ密度が高い時期には、超新星爆発などの破壊的な事象を超えて生き延びられることがわかった。

doi: 10.1038/nature12405

古代のDNA:100万年前のゲノムに期待

Ancient DNA: Towards a million-year-old genome p.34

ほぼ70万年前という年代の骨から得られた完全なウマゲノムの塩基配列が解読された。これによって、ウマ属の進化について手がかりが得られただけでなく、DNAの保存期間の限界も大幅に延長されることになった。

doi: 10.1038/nature12263

がん:遺伝子調節に迫る変異

Cancer: Mutations close in on gene regulation p.35

急性骨髄性白血病患者に由来する200個のサンプルで、DNAとRNAの塩基配列、遺伝子発現とDNA修飾について全ゲノム解析が行われ、データ統合と検証の準備が整った。これは、このがんの包括的解明を進めることになりそうだ。

doi: 10.1038/499035a

地球科学:深い所にある熱い原因

Earth science: Hot and deep p.37

エチオピアのアファール三角地帯は、その下にある構造プレートが離れるように引っ張られているため、注目に値する。モデルによってこの地溝形成に関連した融解過程の原因と深さが明らかになった。

doi: 10.1038/499037a

がん:胆汁酸がつなぐ肥満とがん

Cancer: An acidic link p.37

肥満だといろいろな種類のがんの発症リスクが高くなるが、その理由は不明である。説明となりそうなのは、腸内微生物が作り出す、炎症誘発性と発がん性を併せ持つ胆汁酸の量が、肥満によって増えるという考えである。

doi: 10.1038/nature12404

マラリア:性行動のタイミングを感知する

Malaria: Sensing when it's time for sex p.38

マラリア原虫は発生段階を切り替えることで伝播を促進する。この切り替えは、膜に結合した小胞を介して行われる原虫間での情報交換によって開始されるらしい。

doi: 10.1038/499038a

生物無機化学:合成化合物によって活性化される酵素

Bioinorganic chemistry: Enzymes activated by synthetic components p.40

水素を発生させる酵素であるHydA1の触媒補助部位の合成類似体は、これまで活性が見られるものがなかった。こうした類似体を酵素の活性部位に組み込むことで、活性に何が必要なのかが明らかにされた。

doi: 10.1038/nature12260

Articles

医学:腎明細胞がんの包括的な分子特性解析

Comprehensive molecular characterization of clear cell renal cell carcinoma OPEN p.43

The Cancer Genome Atlas Research Network reports an integrative analysis of more than 400 samples of clear cell renal cell carcinoma based on genomic, DNA methylation, RNA and proteomic characterisation; frequent mutations were identified in the PI(3)K/AKT pathway, suggesting this pathway might be a potential therapeutic target, among the findings is also a demonstration of metabolic remodelling which correlates with tumour stage and severity.

doi: 10.1038/nature12222

分子生物学:53BP1は、DNA損傷でH2Aの15番目のリシンに誘導されたユビキチン標識を読み取る分子である

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark p.50

This study shows that 53BP1 recruitment to sites of DNA damage involves dual recognition of H4K20me2 and H2AK15 histone ubiquitination; the ubiquitin mark and the surrounding epitope on H2A are read by a region of 53BP1 designated the ubiquitination-dependent recruitment motif.

doi: 10.1038/nature12318

Letters

宇宙:散開星団内外での惑星の存在頻度は同じである

The same frequency of planets inside and outside open clusters of stars p.55

The transits of two Sun-like stars by small planets in an open star cluster are reported; such a stellar environment is unlike that of most planet-hosting field stars, and suggests that the occurrence of planets is unaffected by the stellar environment in open clusters.

doi: 10.1038/nature12279

宇宙:後期重爆撃と火山活動による41億〜40億年前の水星全球の地表更新現象

Global resurfacing of Mercury 4.0–4.1 billion years ago by heavy bombardment and volcanism p.59

Analysis of craters on Mercury’s oldest, most heavily cratered terrains shows that they were formed 4.0–4.1 billion years ago, and that the planet’s previous geological history was erased, most probably by voluminous volcanism, which may have been triggered by heavy asteroidal bombardment at that time.

doi: 10.1038/nature12280

物理:真空スクイーズド状態における原子コヒーレンスの放射減衰の低下

Reduction of the radiative decay of atomic coherence in squeezed vacuum p.62

The quantum light–matter interaction between a superconducting artificial atom and squeezed vacuum reduces the transverse radiative decay rate of the atom by a factor of two, allowing the corresponding coherence time, T2, to exceed the ordinary vacuum decay limit, 2T1.

doi: 10.1038/nature12264

生物無機化学:[FeFe]ヒドロゲナーゼのバイオミメティックな組み立てと活性化

Biomimetic assembly and activation of [FeFe]-hydrogenases p.66

Three synthetic mimics of the di-iron centre in [FeFe]-hydrogenases are loaded onto the HydF protein and then transferred to apo-HydA1; full activation of HydA1 was achieved only with the HydF hybrid protein that contained the mimic with an azadithiolate bridge, confirming the presence of this ligand in the active site of native [FeFe]-hydrogenases.

doi: 10.1038/nature12239

地球:アファールの地溝形成後期における融解は深部で起こりかつ高温である

Melting during late-stage rifting in Afar is hot and deep p.70

Large volumes of molten rock break through the Earth’s crust during continental breakup, and here it is shown that the cause is primarily very high mantle temperatures (under a thick plate), rather than plate thinning.

doi: 10.1038/nature12292

進化:更新世中期初頭のウマのゲノム塩基配列を用いたウマ属進化の再検討

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse p.74

A low-coverage draft genome sequence from a horse bone recovered from permafrost dated to approximately 560–780 thousand years ago is presented; this represents the oldest full genome sequence to date by almost an order of magnitude.

doi: 10.1038/nature12323

遺伝学:ヒトにおけるタンパク質存在量の変動と遺伝的制御

Variation and genetic control of protein abundance in humans p.79

A large-scale analysis of variation in human protein levels between individuals is performed using mass-spectrometry-based proteomic technology, and a number of protein quantitative trait loci are identified; over 5% of proteins vary by more than 1.5-fold in their expression levels between individuals, and this variation is not always linked to RNA level.

doi: 10.1038/nature12223

神経科学:ショウジョウバエの摂食運動プログラムに指令を下す1対の介在ニューロン

A single pair of interneurons commands the Drosophila feeding motor program p.83

A pair of Drosophila brain cells is identified and its activation alone is found to induce the fly’s complete feeding motor routine when artificially induced; suppressing or ablating these two neurons eliminates the sugar-induced feeding behaviour, but ablation of just one neuron results in asymmetric movements.

doi: 10.1038/nature12208

細胞:新規細胞表面マーカーを用いた高分解能解析によって明らかになったiPS細胞へのルート

High-resolution analysis with novel cell-surface markers identifies routes to iPS cells p.88

Cellular reprogramming is shown to occur in an ordered, stepwise manner, marked by changes in the cell-surface markers CD44, ICAM1 and Nanog–eGFP; molecular characterization of discrete subpopulations of partially reprogrammed cells shows that reprogramming is not simply the reversal of the normal development process.

doi: 10.1038/nature12243

細胞:ZFP36L2は前期赤芽球バースト形成単位前駆細胞の自己複製に必要である

ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors p.92

Under stress conditions such as acute blood loss or chronic anaemia, glucocorticoids trigger self-renewal of early burst-forming unit–erythroid (BFU–E) progenitors in the spleen, however, the mechanism of glucocorticoid action is not well understood; here the RNA binding protein ZFP36L2 is identified as a transcriptional target of the glucocorticoid receptor in BFU-Es and is shown to be involved in the process of erythroid cell expansion following exposure to glucocorticoids.

doi: 10.1038/nature12215

医学:肥満が誘発する腸内細菌代謝産物が、細胞老化関連分泌表現型を介して肝がん発症を促進する

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome p.97

Obesity is shown in a mouse model of liver cancer to strongly enhance tumorigenesis; a high fat diet alters the composition of intestinal bacteria, leading to more production of the metabolite DCA which, probably together with other factors, induces senescence and the secretion of various senescence-associated cytokines in hepatic stellate cells, thus promoting cancer.

doi: 10.1038/nature12347

免疫:自己組織化インフルエンザナノ粒子ワクチンは広範囲中和性のH1N1抗体を誘導する

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies p.102

A novel platform for vaccines has been developed using self-assembling ferritin-based nanoparticles displaying influenza virus haemagglutinin; the haemagglutinin–nanoparticle vaccine induces more broad and potent neutralizing antibodies against diverse virus strains than a licensed influenza vaccine in mice and ferrets.

doi: 10.1038/nature12202

構造生物学:真核生物カルシウム/プロトン交換輸送体で見られる交互アクセスの構造的基盤

Structural basis for alternating access of a eukaryotic calcium/proton exchanger p.107

The X-ray crystal structure of a member of the Ca2+/H+ (CAX) antiporter family from Saccharomyces cerevisiae in a cytosol-facing, substrate-bound conformation is solved; using the structure, a mechanism by which members of the Ca2+:cation (CaCA) superfamily facilitate Ca2+ transport across cellular membranes is proposed.

doi: 10.1038/nature12233

構造生物学:重要なシャペロンであるFACTによるヒストンH2A–H2B認識の構造基盤

Structural basis of histone H2A–H2B recognition by the essential chaperone FACT p.111

The crystal structure of the FACT histone chaperone domain Spt16M in complex with the H2A–H2B heterodimer is solved; Spt16M makes several interactions with histones and seems to block the interaction of H2B with DNA, which could explain how FACT destabilizes nucleosomes to promote transcription.

doi: 10.1038/nature12242

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