Volume 543 Number 7646



Trump faces backlash on health-agency cuts p.463

Crippling the US National Institutes of Health might increase resistance to other attacks on science.

doi: 10.1038/nature.2017.21664


The FDA chief must not be a proxy for industry p.463

Trump’s pick for the US regulatory agency will bring experience and a clear vision — as well as ties to industry.

doi: 10.1038/nature.2017.21661


Birds of play demonstrate the infectious power of emotion p.464

New Zealand parrots provide the latest support for a popular theory of crowd behaviour.

doi: 10.1038/543464a



US science agencies face deep cuts in Trump budget p.471

The Environmental Protection Agency and the National Institutes of Health are big losers — but planetary science at NASA stands to gain.

doi: 10.1038/nature.2017.21652


Mathematicians create warped worlds in virtual reality p.473

Immersive experience set to become accessible to all.

doi: 10.1038/543473a


South Korea’s scientists seek change amid political chaos p.474

President’s impeachment creates opportunity to shift how nation supports basic research.

doi: 10.1038/543474a


South Africa’s San people issue ethics code to scientists p.475

The indigenous people — known for their click languages — are the first in Africa to draft guidelines for researchers.

doi: 10.1038/543475a

今年のアーベル賞は、データ解析に広く応用されるウェーブレット理論への貢献で、フランスのYves Meyer氏に。

‘Wavelet revolution’ pioneer scoops top maths award p.476

Yves Meyer wins the Abel Prize for role in theory with data applications from digital cinema to pinpointing gravitational waves.

doi: 10.1038/543476a

News Features


How to hunt for a black hole with a telescope the size of Earth p.478

世界各地のさまざまな電波望遠鏡をリンクさせることで、「事象の地平線」を画像化しようとする望遠鏡計画(Event Horizon Telescope)がいよいよ始動する。

doi: 10.1038/543478a

News & Views


Palaeontology: Dividing the dinosaurs p.494


doi: 10.1038/543494a


Microbiology: Bacterial transmission tactics p.495

今回、肺に感染するMycobacterium abscessus菌株のゲノム塩基配列解読によって、この細菌の感染モードが環境経由のものからヒト間伝染に変わる可能性が示唆されている。この知見は、臨床に影響を及ぼす。

doi: 10.1038/543495a


Condensed-matter physics: Vibrations mapped by an electron beam p.497


doi: 10.1038/543497a


Ecology: A helping habitat for bumblebees p.498


doi: 10.1038/nature21897


Finding latent needles in a haystack p.499


doi: 10.1038/nature21899



A new hypothesis of dinosaur relationships and early dinosaur evolution p.501

Analysis of a wide range of dinosaurs and dinosauromorphs recovers a sister-taxon relationship between Ornithischia and Theropoda, calling for the redefinition of all the major clades within Dinosauria and the revival of the clade Ornithoscelida.

doi: 10.1038/nature21700


Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1 p.507

Increasing expression of the autism-associated gene Ube3a, either alone or in combination with seizures, not only impairs sociability in mice but also reduces expression of the synaptic organizer Cbln1 in the ventral tegmental area, thus weakening glutamatergic transmission.

doi: 10.1038/nature21678


Root microbiota drive direct integration of phosphate stress and immunity p.513

In Arabidopsis thaliana, a genetic network that controls the phosphate stress response also influences the structure of the root microbiome community, even under non-stress phosphate conditions.

doi: 10.1038/nature21417


Complex multi-enhancer contacts captured by genome architecture mapping p.519

A technique called genome architecture mapping (GAM) involves sequencing DNA from a large number of thin nuclear cryosections to develop a map of genome organization without the limitations of existing 3C-based methods.

doi: 10.1038/nature21411



Simultaneous tracking of spin angle and amplitude beyond classical limits p.525

Simultaneous precise measurement of the non-commuting observables spin angle and spin amplitude is achieved by directing the error due to quantum measurement back-action into an unmeasured spin component.

doi: 10.1038/nature21434


Mapping vibrational surface and bulk modes in a single nanocube p.529

Spatial mapping of optical and acoustic, bulk and surface vibrational modes in magnesium oxide nanocubes is demonstrated using a single electron probe.

doi: 10.1038/nature21699


Mechanical metamaterials at the theoretical limit of isotropic elastic stiffness p.533

Finite-element models are used to identify a material geometry that achieves the theoretical bounds on isotropic elastic stiffness—a combination closed-cell cubic and octet foam.

doi: 10.1038/nature21075


Remote site-selective C–H activation directed by a catalytic bifunctional template p.538

A method is described for selectively activating remote C–H bonds in heterocycles by using a catalytic template that binds by reversible coordination instead of a covalent linkage, removing the need for specific functional groups on which to attach the template.

doi: 10.1038/nature21418


Evidence for a Fe3+-rich pyrolitic lower mantle from (Al,Fe)-bearing bridgmanite elasticity data p.543

The authors report single-crystal elasticity data on (Al,Fe)-bearing bridgmanite and show that its elastic behaviour is markedly different from that of the MgSiO3 endmember.

doi: 10.1038/nature21390


Bumblebee family lineage survival is enhanced in high-quality landscapes p.547

Analysis of three wild-caught bumblebee species shows that family lineage survival and persistence is significantly increased between successive colony cycle stages with the proportion of high-value foraging habitat near the natal colony.

doi: 10.1038/nature21709


KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks p.550

Genomic analyses of KRAB-containing zinc-finger proteins and the transposable elements to which they bind show that a co-evolutionary arms race was not the only driver of their evolution.

doi: 10.1038/nature21683


Phytoplankton can actively diversify their migration strategy in response to turbulent cues p.555

Here, marine phytoplankton are shown to diversify their migratory strategy in response to turbulent cues through a rapid change in shape, thus challenging a fundamental paradigm in oceanography that phytoplankton are passively at the mercy of ocean turbulence.

doi: 10.1038/nature21415


Early antibody therapy can induce long-lasting immunity to SHIV p.559

Early administration of broadly neutralizing antibodies in a macaque SHIV infection model is associated with very low levels of persistent viraemia, which leads to the establishment of T-cell immunity and resultant long-term infection control.

doi: 10.1038/nature21435

ウイルス学:CD32aは複製可能プロウイルスを含んだCD4 T細胞HIVリザーバーのマーカーである

CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses p.564

CD32a expression is induced on the surface of HIV-1-infected quiescent CD4 T cells, and could thus be used as a biomarker to facilitate future study of how the virus persists in cellular reservoirs in infected hosts.

doi: 10.1038/nature21710


DND1 maintains germline stem cells via recruitment of the CCR4–NOT complex to target mRNAs p.568

The vertebrate-conserved and germline-specific RNA-binding protein DND1 recruits the CCR4–NOT deadenylase complex to destabilize its mRNA targets and is required for the maintenance of germline stem cells.

doi: 10.1038/nature21690

分子生物学:RNA m6Aメチル化は紫外線によるDNA損傷応答を調節する

RNA m6A methylation regulates the ultraviolet-induced DNA damage response p.573

Methylation at the 6 position of adenosine (m6A) in RNA is rapidly and transiently induced at DNA damage sites in response to ultraviolet irradiation.

doi: 10.1038/nature21671

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