Volume 443 Number 7111

Editorial

To build bridges, or to burn them p.481

Environmentalists who have grown impatient with science and technology need not be dismissed as beyond the reach of reason.

doi: 10.1038/443481a

News

Youthful duo snags a swift Nobel for RNA control of genes p.488

Award comes just eight years after publication.

doi: 10.1038/443488a

Cosmic ripples net physics prize p.489

Vision of early Universe makes its mark.

doi: 10.1038/443489a

News & Views

Nanotechnology: Downsizing SQUIDs p.517

doi: 10.1038/443517a

News and Views Feature

Genetics: Junk DNA as an evolutionary force p.521

Transposable elements were long dismissed as useless, but they are emerging as major players in evolution. Their interactions with the genome and the environment affect how genes are translated into physical traits.

doi: 10.1038/443521a

Articles

Genome-wide genetic analysis of polyploidy in yeast p.541

doi: 10.1038/nature05178

AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP p.548

doi: 10.1038/nature05124

Letters

Quantum teleportation between light and matter p.557

doi: 10.1038/nature05136

Rapid subtropical North Atlantic salinity oscillations across Dansgaard–Oeschger cycles p.561

doi: 10.1038/nature05121

Lithium isotope evidence for subduction-enriched mantle in the source of mid-ocean-ridge basalts p.565

doi: 10.1038/nature05144

Reassembly of shattered chromosomes in Deinococcus radiodurans p.569

doi: 10.1038/nature05160

Functional epistasis on a common MHC haplotype associated with multiple sclerosis p.574

doi: 10.1038/nature05133

Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite p.582

doi: 10.1038/nature05149

Identification of a mammalian mitochondrial porphyrin transporter p.586

doi: 10.1038/nature05125

Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery p.590

doi: 10.1038/nature05175

Co-evolution of transcriptional and post-translational cell-cycle regulation p.594

doi: 10.1038/nature05186

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