Research press release


Nature Genetics

Stop and smell the rose genome



今回、Mohammed Bendahmaneたちの研究グループは、長鎖配列解読技術と小胞子培養プロトコルを適用して、モダンローズの一種であるコウシンバラ(Rosa chinensis、「オールド・ブラッシュ」と呼ばれる)の高精度ゲノムを組み立てた。このゲノム配列は、現在の植物ゲノム塩基配列の中で最も完全な形を有するものの1つである。また、Bendahmaneたちは、コウシンバラと他の植物(イチゴ、アンズ、モモ、リンゴ、セイヨウナシ)との比較ゲノム解析を行い、バラの祖先と進化について研究し、ゲノム情報と生化学的解析、分子解析を組み合わせることにより、バラの色と匂いに関連する分子経路を新たに同定した。


The genome sequence of the modern rose is the subject of a paper published online this week in Nature Genetics. This reference provides molecular insights into the genes and metabolic processes responsible for the unique color and smell traits of the flower.

Modern roses, prized for their beauty and scent, have complex genomes that need to be decoded to fully harness the genetic information as a means to improve upon the species. Previous rose genome assemblies, however, were highly fragmented and therefore difficult to decipher.

Mohammed Bendahmane and colleagues applied long-read sequencing and a microspore culturing protocol to assemble a high-quality genome of Rosa chinensis, a modern rose species known as ‘Old Blush’. This resulted in one of the most intact plant genome sequences in existence. The authors were able to perform comparative genomic analyses with other plants, including strawberry, apricot, peach, apple and pear, to explore rose ancestry and evolution. The genomic information combined with biochemical and molecular analyses uncovers new genetic pathways relating to color and scent.

The authors also identify other candidate genes for flowering, which could be potential targets in genetically improving rose cultivars. The authors suggest that this genomic resource and the new insights presented lay the groundwork for researchers and breeders to manipulate flowering, color, water-use efficiency, strengthen scent, or increase the vase life of roses.

doi: 10.1038/s41588-018-0110-3


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