Research Abstract


Carbon nanotube–liposome supramolecular nanotrains for intelligent molecular-transport systems

2012年11月27日 Nature Communications 3 : 1226 doi: 10.1038/ncomms2233


都 英次郎1, 河野 健司2, 弓場 英司2, 細川 千絵1, 永井 秀典1 & 萩原 義久1

  1. 独立行政法人 産業技術総合研究所(AIST)健康工学研究部門(HRI)
  2. 大阪府立大学 大学院工学研究科 物質・化学系専攻 応用化学分野
Biological network systems, such as inter- and intra-cellular signalling systems, are handled in a sophisticated manner by the transport of molecular information. Over the past few decades, there has been a growing interest in the development of synthetic molecular-transport systems. However, several key technologies have not been sufficiently realized to achieve optimum performance of transportation methods. Here we show that a new type of supramolecular system comprising of carbon nanotubes and liposomes enables the directional transport and controlled release of carrier molecules, and allows an enzymatic reaction at a desired area. The study highlights important progress that has been made towards the development of biomimetic molecular-transport systems and various lab-on-a-chip applications, such as medical diagnosis, sensors, bionic computers and artificial biological networks.