Research Abstract


Brain response patterns to economic inequity predict present and future depression indices

2017年10月2日 Nature Human Behaviour 1 : 748 doi: 10.1038/s41562-017-0207-1



Toshiko Tanaka, Takao Yamamoto and Masahiko Haruno

Corresponding Author

春野 雅彦
情報通信研究機構 脳情報通信融合研究センター

Widening economic inequity has been suggested to associate with depression. However, little is known about the underlying neural mechanisms of this link. Here, we demonstrate that functional magnetic resonance imaging activity patterns in the amygdala and hippocampus induced by the inequity between the self and other rewards during an economic game can predict participants’ present and future (measured one year later) depression indices. Such predictions were not possible using participant’s behavioural and socio-economic status measures. These findings suggest that sensitivity to economic inequity has a critical effect on human mood states, and the amygdala and hippocampus play a key role in individual differences in the effect.