ChatGPT is a black box: how AI research can break it open p.671

Despite their wide use, large language models are still mysterious. Revealing their true nature is urgent and important.

doi: 10.1038/d41586-023-02366-2

The United Kingdom needs to welcome international researchers to thrive p.672

Scientific strength does not come from severing long-standing relationships or turning away talent from around the world.

doi: 10.1038/d41586-023-02367-1

As COVID-19 cases rose, so did diabetes — no one knows why p.677

The spike in childhood type 1 diabetes opened new avenues for researchers to explore the cause of the disease.

doi: 10.1038/d41586-023-02322-0

The true cost of science’s language barrier for non-native English speakers p.678

Survey quantifies the extra time that researchers whose first language isn’t English need to read, write and present data.

doi: 10.1038/d41586-023-02320-2

Had COVID but no symptoms? You might have this genetic mutation p.679

A common variant in an immune-system gene is linked with a much higher chance of dodging symptoms after SARS-CoV-2 infection.

doi: 10.1038/d41586-023-02318-w

Oil from the Amazon? Proposal to drill at river’s mouth worries researchers p.680

Energy firm Petrobras says any leaked oil would not reach the Brazilian coast, but scientists are concerned about a vast reef nearby.

doi: 10.1038/d41586-023-02187-3

Can India’s new billion-dollar funding agency boost research? p.681

India’s proposed National Research Foundation will shake up the scientific landscape to encourage a culture of research.

doi: 10.1038/d41586-023-02336-8

Alzheimer’s drug donanemab helps most when taken at earliest disease stage, study finds p.682

But the drug, an antibody that attacks the protein amyloid, does not work as well in people with more advanced disease.

doi: 10.1038/d41586-023-02321-1

Cell ‘atlases’ offer unprecedented view of placenta, intestines and kidneys p.683

Organ mapping studies show how kidney cells become diseased, and how cells from a fetus invade and remodel blood vessels in the lining of the uterus.

doi: 10.1038/d41586-023-02348-4

Deep-sea mining could soon be approved — how bad is it? p.684

doi: 10.1038/d41586-023-02290-5

ChatGPT broke the Turing test — the race is on for new ways to assess AI p.686

doi: 10.1038/d41586-023-02361-7

Heat-assisted imaging enables day-like visibility at night p.699

An imaging technique that uses a neural-network model to obtain physical information from infrared radiation improves on existing techniques in low-visibility situations, and could be deployed immediately in autonomous vehicles.

doi: 10.1038/d41586-023-02333-x

Dynamics of protein droplets revealed by bridging multiple scales p.700

Many biological processes rely on proteins that aggregate into droplets governed by dynamics that span myriad scales. A clever combination of spectroscopy and simulation offers a way to probe these diverse dynamics.

doi: 10.1038/d41586-023-02215-2

Long La Niña events could rise in frequency as the planet warms p.702

La Niña events involve a cooling of the tropical Pacific Ocean, and can last for two years or more, prolonging their impact. Climate simulations reveal that global warming could cause multi-year La Niña events to become more frequent.

doi: 10.1038/d41586-023-02331-z

A sustainable way to control the parasitic disease schistosomiasis p.703

A trial in Senegal has tested an innovative method for tackling a common human parasitic disease. The approach reduced infection numbers and also offered agricultural and economic benefits.

doi: 10.1038/d41586-023-02178-4

Sixty years since the report of global lead pollution p.704

The 1963 discovery that even the vast oceans were highly contaminated with lead from car exhausts sparked debate and policy changes that benefited the health of millions — and revolutionized the practices of marine biogeochemistry.

doi: 10.1038/d41586-023-02196-2

CAR T therapy beyond cancer: the evolution of a living drug p.707

doi: 10.1038/s41586-023-06243-w

A massive quiescent galaxy at redshift 4.658 p.716

doi: 10.1038/s41586-023-06158-6

Spectroscopic identification of water emission from a main-belt comet p.720

doi: 10.1038/s41586-023-06152-y

Diverse organic-mineral associations in Jezero crater, Mars p.724

doi: 10.1038/s41586-023-06143-z

Spin state and deep interior structure of Mars from InSight radio tracking p.733

doi: 10.1038/s41586-023-06150-0

Generation of genuine entanglement up to 51 superconducting qubits p.738

doi: 10.1038/s41586-023-06195-1

Heat-assisted detection and ranging p.743

doi: 10.1038/s41586-023-06174-6

Femtosecond proton transfer in urea solutions probed by X-ray spectroscopy p.749

doi: 10.1038/s41586-023-06182-6

Fluidic self-assembly for MicroLED displays by controlled viscosity p.755

doi: 10.1038/s41586-023-06167-5

Accelerating the energy transition towards photovoltaic and wind in China p.761

doi: 10.1038/s41586-023-06180-8

The social value of offsets p.768

doi: 10.1038/s41586-023-06153-x

Increased occurrences of consecutive La Niña events under global warming p.774

doi: 10.1038/s41586-023-06236-9

A planetary health innovation for disease, food and water challenges in Africa p.782

doi: 10.1038/s41586-023-06313-z

Indirect effects shape species fitness in coevolved mutualistic networks p.788

doi: 10.1038/s41586-023-06319-7

Cancer aneuploidies are shaped primarily by effects on tumour fitness p.793

doi: 10.1038/s41586-023-06266-3

Spatially resolved multiomics of human cardiac niches p.801

doi: 10.1038/s41586-023-06311-1

Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide p.811

doi: 10.1038/s41586-023-06301-3

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection p.819

doi: 10.1038/s41586-023-06322-y

A framework for individualized splice-switching oligonucleotide therapy p.828

doi: 10.1038/s41586-023-06277-0

Gut microbial fatty acid isomerization modulates intraepithelial T cells p.837

doi: 10.1038/s41586-023-06265-4

Remote neuronal activity drives glioma progression through SEMA4F p.844

doi: 10.1038/s41586-023-06267-2

p53 governs an AT1 differentiation programme in lung cancer suppression p.851

doi: 10.1038/s41586-023-06253-8

KRAS(G12D) drives lepidic adenocarcinoma through stem-cell reprogramming p.860

doi: 10.1038/s41586-023-06324-w

Complementary Alu sequences mediate enhancer–promoter selectivity p.868

doi: 10.1038/s41586-023-06323-x

Extreme dynamics in a biomolecular condensate p.876

doi: 10.1038/s41586-023-06329-5