In space, failure is an option — often the only one p.223

Space companies should not lose heart when things go wrong. The first Moon missions failed repeatedly — and provided lessons on how to achieve success in space and beyond.

doi: 10.1038/d41586-023-01547-3

COVID’s future: mini-waves rather than seasonal surges p.229

Three years after the start of the pandemic, SARS-CoV-2 shows no signs of settling into a seasonal pattern of spread, like influenza has.

doi: 10.1038/d41586-023-01437-8

Air pollution in China is falling — but there is a long way to go p.230

Easy gains from upgrading power-plant smokestacks will be strengthened only by deeper policy changes.

doi: 10.1038/d41586-023-01452-9

‘Armed groups entered the lab’: Sudan’s researchers flee violent military conflict p.231

Clashes have left hospitals and universities without water and power — and vulnerable to takeover by armed groups.

doi: 10.1038/d41586-023-01478-z

Alzheimer’s drug donanemab: what promising trial means for treatments p.232

Results suggest that the amyloid-targeting drug candidate slows cognitive decline in some people, but questions remain over its potential side effects.

doi: 10.1038/d41586-023-01537-5

Wuhan market samples fail to shed further light on COVID origins p.233

New analysis of genomic data from market swabs highlights their limitations.

doi: 10.1038/d41586-023-01483-2

‘A good day’: FDA approves world’s first RSV vaccine p.234

Green light from US regulatory agency for GSK’s jab caps off a decades-long quest.

doi: 10.1038/d41586-023-01529-5

How generative AI is building better antibodies p.235

Language models similar to those behind ChatGPT have been used to improve antibody therapies against COVID-19, Ebola and other viruses.

doi: 10.1038/d41586-023-01516-w

Mind-reading machines are here: is it time to worry? p.236

doi: 10.1038/d41586-023-01486-z

‘The best way to get it right is to listen to us’ — autistic people argue for a stronger voice in research p.238

doi: 10.1038/d41586-023-01549-1

Human embryo science: can the world’s regulators keep pace? p.242

doi: 10.1038/d41586-023-01550-8

A redrawn map for the human motor cortex p.253

The human brain’s motor cortex is often regarded as a linear map with discrete sections, each controlling different parts of the body. The discovery that portions of the motor cortex have other functions points to a different type of map.

doi: 10.1038/d41586-023-01350-0

Superconducting qubits cover new distances p.254

Superconducting quantum bits, a promising platform for future quantum computers, have been entangled over a separation of 30 metres, with a performance that enabled the demonstration of a milestone in quantum physics.

doi: 10.1038/d41586-023-01488-x

Human pangenome supports analysis of complex genomic regions p.256

A pangenome is a collection of DNA sequences that reveals genetic variation between individuals. Four scientists discuss the generation of a human pangenome, and what insights can be gained from it.

doi: 10.1038/d41586-023-01490-3

Salty seas sway global glacial cycles p.258

Analysis of microfossils in marine sediments spanning the past 1.2 million years suggests that increased intrusion of highly saline waters from the Indian Ocean into the South Atlantic propelled Earth’s deglaciations during this period.

doi: 10.1038/d41586-023-01489-w

COVID pandemic increased racial disparities in US prison populations p.259

A public data set on the size and racial composition of US prison populations has been generated. Its analysis indicates how biases in sentencing lengths shape prisons’ racial make-up in the United States.

doi: 10.1038/d41586-023-01023-y

ii] emitters around a C iv absorption complex at redshift 5.7" rel="external">Compact [C ii] emitters around a C iv absorption complex at redshift 5.7 p.261

doi: 10.1038/s41586-023-05901-3

Loophole-free Bell inequality violation with superconducting circuits p.265

doi: 10.1038/s41586-023-05885-0

Many-body cavity quantum electrodynamics with driven inhomogeneous emitters p.271

doi: 10.1038/s41586-023-05884-1

Partitioning of diluted anyons reveals their braiding statistics p.277

doi: 10.1038/s41586-023-05883-2

Tunable electron–flexural phonon interaction in graphene heterostructures p.282

doi: 10.1038/s41586-023-05879-y

Concurrent self-assembly of RGB microLEDs for next-generation displays p.287

doi: 10.1038/s41586-023-05889-w

High-throughput printing of combinatorial materials from aerosols p.292

doi: 10.1038/s41586-023-05898-9

Near-frictionless ion transport within triazine framework membranes p.299

doi: 10.1038/s41586-023-05888-x

Indian Ocean salinity build-up primes deglacial ocean circulation recovery p.306

doi: 10.1038/s41586-023-05866-3

A draft human pangenome reference p.312

doi: 10.1038/s41586-023-05896-x

Increased mutation and gene conversion within human segmental duplications p.325

doi: 10.1038/s41586-023-05895-y

Recombination between heterologous human acrocentric chromosomes p.335

doi: 10.1038/s41586-023-05976-y

COVID-19 amplified racial disparities in the US criminal legal system p.344

doi: 10.1038/s41586-023-05980-2

A somato-cognitive action network alternates with effector regions in motor cortex p.351

doi: 10.1038/s41586-023-05964-2

Learnable latent embeddings for joint behavioural and neural analysis p.360

doi: 10.1038/s41586-023-06031-6

Inhibitory input directs astrocyte morphogenesis through glial GABA_BR p.369

doi: 10.1038/s41586-023-06010-x

Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance p.377

doi: 10.1038/s41586-023-06026-3

A druggable copper-signalling pathway that drives inflammation p.386

doi: 10.1038/s41586-023-06017-4

Noncoding translation mitigation p.395

doi: 10.1038/s41586-023-05946-4

Complete integration of carbene-transfer chemistry into biosynthesis p.403

doi: 10.1038/s41586-023-06027-2

Structural atlas of a human gut crassvirus p.409

doi: 10.1038/s41586-023-06019-2

Ligand and G-protein selectivity in the κ-opioid receptor p.417

doi: 10.1038/s41586-023-06030-7