The water crisis is worsening. Researchers must tackle it together p.611

It’s unacceptable that millions living in poverty still lack access to safe water and basic sanitation. Nature Water will help researchers to find a way forward.

doi: 10.1038/d41586-023-00182-2

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use p.612

As researchers dive into the brave new world of advanced AI chatbots, publishers need to acknowledge their legitimate uses and lay down clear guidelines to avoid abuse.

doi: 10.1038/d41586-023-00191-1

Multimillion-dollar trade in paper authorships alarms publishers p.617

Journals have begun retracting publications with suspicious links to sites trading in author positions.

doi: 10.1038/d41586-023-00062-9

Alzheimer’s drug saga prompts journal to scrutinize whistle-blowers p.618

Publication requires complainants to disclose financial conflicts in the wake of controversy over Cassava Sciences’ experimental treatment simufilam.

doi: 10.1038/d41586-023-00050-z

ChatGPT listed as author on research papers: many scientists disapprove p.620

At least four articles credit the AI tool as a co-author, as publishers scramble to regulate its use.

doi: 10.1038/d41586-023-00107-z

The plan to ‘Trump-proof’ US science against political meddling p.621

Guidance document calls on agencies to draft protective scientific-integrity policies for White House review within two months.

doi: 10.1038/d41586-022-03307-1

China is opening up after 3 years — what does it mean for research? p.622

The government has abandoned its ‘zero-COVID’ policy and researchers from inside and outside the country are organizing to meet.

doi: 10.1038/d41586-023-00091-4

Researchers blast US agency’s decision not to collect LGBT+ data p.624

Scientists call for the National Science Foundation to add a question about sexual orientation to its 2023 workforce surveys.

doi: 10.1038/d41586-023-00082-5

Star graveyard revealed in super-clear image of the Milky Way p.625

Detailed radio observations turn up previously unseen remnants of dying stars in the Galaxy.

doi: 10.1038/d41586-023-00110-4

The race to supercharge cancer-fighting T cells p.626

doi: 10.1038/d41586-023-00177-z

No stopping with a short-stem transfer RNA p.631

Messenger RNA has 64 possible triplet sequences, or codons, three of which usually terminate protein synthesis. But some organisms can use all codons to specify amino acids, thanks in part to a surprising feature of a transfer RNA.

doi: 10.1038/d41586-022-04585-5

Unconventional tracers show that spring waters on Mount Fuji run deep p.632

A trio of tracers has debunked a long-held model of the origins of spring water on Mount Fuji, revealing interactions between shallow and deep aquifer layers, and providing a fresh approach for probing mountain groundwater flow.

doi: 10.1038/d41586-022-04561-z

First full views of a CRISPR-guided system for gene insertion p.634

CRISPR–Cas is a bacterial defence system that can attack invading DNA to protect host cells, or help to insert DNA safely into the genome. Structures of this latter type of CRISPR–Cas system have now been visualized.

doi: 10.1038/d41586-022-04584-6

Machine learning classifies catalytic-reaction mechanisms p.635

The study of how chemical reactions work is key to the design of new reactions, but relies on hard work and expert knowledge. A machine-learning tool has been developed that could change the way this challenge is approached.

doi: 10.1038/d41586-023-00145-7

Targets mapped for almost all human kinase enzymes p.637

A computational resource can identify candidate protein targets for almost all members of a major class of kinase enzyme in humans, with implications for understanding cell signalling in health and disease.

doi: 10.1038/d41586-022-04583-7

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies p.639

doi: 10.1038/s41586-022-05546-8

Down-conversion of a single photon as a probe of many-body localization p.650

doi: 10.1038/s41586-022-05615-y

In-plane charged domain walls with memristive behaviour in a ferroelectric film p.656

doi: 10.1038/s41586-022-05503-5

Attosecond field emission p.662

doi: 10.1038/s41586-022-05577-1

A wearable cardiac ultrasound imager p.667

doi: 10.1038/s41586-022-05498-z

Regulating surface potential maximizes voltage in all-perovskite tandems p.676

doi: 10.1038/s41586-022-05541-z

Rotational multimaterial printing of filaments with subvoxel control p.682

doi: 10.1038/s41586-022-05490-7

Organic reaction mechanism classification using machine learning p.689

doi: 10.1038/s41586-022-05639-4

Social trauma engages lateral septum circuitry to occlude social reward p.696

doi: 10.1038/s41586-022-05484-5

Discriminatory attitudes against unvaccinated people during the pandemic p.704

doi: 10.1038/s41586-022-05607-y

A molecular network of conserved factors keeps ribosomes dormant in the egg p.712

doi: 10.1038/s41586-022-05623-y

Undecaprenyl phosphate translocases confer conditional microbial fitness p.721

doi: 10.1038/s41586-022-05569-1

Two broadly conserved families of polyprenyl-phosphate transporters p.729

doi: 10.1038/s41586-022-05587-z

Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination p.735

doi: 10.1038/s41586-022-05609-w

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects p.743

doi: 10.1038/s41586-022-05593-1

Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment p.751

doi: 10.1038/s41586-022-05584-2

An atlas of substrate specificities for the human serine/threonine kinome p.759

doi: 10.1038/s41586-022-05575-3

Structure-based design of bitopic ligands for the μ-opioid receptor p.767

doi: 10.1038/s41586-022-05588-y

Structures of the holo CRISPR RNA-guided transposon integration complex p.775

doi: 10.1038/s41586-022-05573-5

Structural basis for intrinsic transcription termination p.783

doi: 10.1038/s41586-022-05604-1