Ending racism is key to better science: a message from Nature’s guest editors p.419

This special issue is our ‘message in a bottle’ from the troubled ship of science. We urge readers to find it. Open it. Act on its contents.

doi: 10.1038/d41586-022-03247-w

Nature thanks the guest editors of our racism in science special issue p.420

This special issue is part of Nature’s commitment to change. We thank our inspiring guest editors for helping us to make it happen.

doi: 10.1038/d41586-022-03248-9

Human brain cells implanted in rats prompt excitement — and concern p.427

Rat–human hybrid brains offer new ways to study human neurological disorders, but also raise ethical questions.

doi: 10.1038/d41586-022-03238-x

COVID prompts global surge in labs that handle dangerous pathogens p.428

India, Singapore and the Philippines are among those building new laboratories certified as biosafety level 3 or above, but some researchers worry about the costs and risks.

doi: 10.1038/d41586-022-03181-x

‘I could not keep silent’: Iranian physicist resigns to join protests p.430

doi: 10.1038/d41586-022-03246-x

Energy crisis squeezes science at CERN and other major facilities p.431

LHC to end 2022 data-taking season two weeks early to save on electricity, among other measures.

doi: 10.1038/d41586-022-03257-8

China’s first solar observatory aims to solve mysteries of the Sun’s eruptions p.432

The mission, scheduled to launch on Sunday, will also help to improve forecasts of damaging space weather.

doi: 10.1038/d41586-022-03180-y

Neurons in a dish learn to play Pong — what’s next? p.433

Cellular version of computer game challenges assumptions about intelligence.

doi: 10.1038/d41586-022-03229-y

‘It’s a constant hum’: a planetary geologist calls out racism in academia p.434

doi: 10.1038/d41586-022-03250-1

Computer science has a racism problem: these researchers want to fix it p.440

doi: 10.1038/d41586-022-03251-0

Skin colour affects the accuracy of medical oxygen sensors p.449

COVID-19 broadened the use of pulse oximeters for rapid blood-oxygen readings, but it also highlighted the fact that skin pigmentation alters measurements. Two groups of researchers analyse this issue, and its effects on people with dark skin.

doi: 10.1038/d41586-022-03161-1

The unseen Black faces of AI algorithms p.451

An audit of commercial facial-analysis tools found that dark-skinned faces are misclassified at a much higher rate than are faces from any other group. Four years on, the study is shaping research, regulation and commercial practices.

doi: 10.1038/d41586-022-03050-7

Neurons that control walking go round in circles p.453

Evidence from turtles and computer models indicates that a pattern of neuronal activity known as rotational dynamics governs locomotion. The finding challenges long-standing models of locomotor control.

doi: 10.1038/d41586-022-02238-1

The first genomic portrait of a Neanderthal family p.454

Ancient genomic data have been retrieved for 13 Neanderthals from 2 caves in Siberia. The genomes provide unprecedented insights into the social organization of Neanderthal communities.

doi: 10.1038/d41586-022-03005-y

Embrace wobble to level flight without a horizon p.455

The apparent motion of a flier’s surroundings is shown to stabilize its flight by providing information about its orientation. Lapses in information are overcome through the effects of sensor noise and body oscillations.

doi: 10.1038/d41586-022-03217-2

New catalogue of Earth’s ecosystems p.457

Echoing the hierarchical Linnaean system for naming species, ecologists have developed a definitive classification of Earth’s ecosystems. This feat, achieved by a massive effort, could anchor conservation efforts for decades to come.

doi: 10.1038/d41586-022-03078-9

The gas about Stephan’s Quintet reveals a history of collision p.458

A highly sensitive observation has revealed a large, diffuse gas feature centred on the galaxy group Stephan’s Quintet — prompting a revision of our understanding of gas dynamics in the outer regions of galaxy groups.

doi: 10.1038/d41586-022-03218-1

i structure associated with Stephan’s Quintet" rel="external">A 0.6 Mpc H i structure associated with Stephan’s Quintet p.461

doi: 10.1038/s41586-022-05206-x

A dense 0.1-solar-mass star in a 51-minute-orbital-period eclipsing binary p.467

doi: 10.1038/s41586-022-05195-x

Entanglement-enhanced matter-wave interferometry in a high-finesse cavity p.472

doi: 10.1038/s41586-022-05197-9

Enhanced interactions of interlayer excitons in free-standing heterobilayers p.478

doi: 10.1038/s41586-022-05193-z

Accommodating unobservability to control flight attitude with optic flow p.485

doi: 10.1038/s41586-022-05182-2

Low-hysteresis shape-memory ceramics designed by multimode modelling p.491

doi: 10.1038/s41586-022-05210-1

Nonlinear decision-making with enzymatic neural networks p.496

doi: 10.1038/s41586-022-05218-7

Self-assembly of emulsion droplets through programmable folding p.502

doi: 10.1038/s41586-022-05198-8

From planetary to regional boundaries for agricultural nitrogen pollution p.507

doi: 10.1038/s41586-022-05158-2

A function-based typology for Earth’s ecosystems p.513

doi: 10.1038/s41586-022-05318-4

Genetic insights into the social organization of Neanderthals p.519

doi: 10.1038/s41586-022-05283-y

Movement is governed by rotational neural dynamics in spinal motor networks p.526

doi: 10.1038/s41586-022-05293-w

A wheat resistosome defines common principles of immune receptor channels p.532

doi: 10.1038/s41586-022-05231-w

Antibiotic combinations reduce Staphylococcus aureus clearance p.540

doi: 10.1038/s41586-022-05260-5

The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death p.547

doi: 10.1038/s41586-022-05259-y

An LKB1–mitochondria axis controls T_H17 effector function p.555

doi: 10.1038/s41586-022-05264-1

Gut bacteria alleviate smoking-related NASH by degrading gut nicotine p.562

doi: 10.1038/s41586-022-05299-4

Structure of the NuA4 acetyltransferase complex bound to the nucleosome p.569

doi: 10.1038/s41586-022-05303-x

Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA p.575

doi: 10.1038/s41586-022-05324-6

Bespoke library docking for 5-HT_2A receptor agonists with antidepressant activity p.582

doi: 10.1038/s41586-022-05258-z