The EU can simultaneously end dependence on Russia and meet climate goals p.7

Nations that relinquish reliance on Russia’s fossil fuels should quickly transition to clean energy.

doi: 10.1038/d41586-022-00920-y

Time to recognize authorship of open data p.8

The open data revolution won’t happen unless the research system values the sharing of data as much as authorship on papers.

doi: 10.1038/d41586-022-00921-x

Exclusive: Documents reveal NASA’s internal struggles over renaming Webb telescope p.15

E-mails show agency’s controversial response to astronomers concerned about past LGBT+ discrimination.

doi: 10.1038/d41586-022-00845-6

Will Omicron finally overpower China’s COVID defences? p.17

The country needs to control the virus until it has boosted vaccination rates in elderly people and reinforced the health-care system.

doi: 10.1038/d41586-022-00884-z

Biden bids again to boost science spending — but faces long odds p.18

The US president wants huge increases for clean energy and public health, but a divided Congress might not go along with the plan.

doi: 10.1038/d41586-022-00897-8

Can drugs reduce the risk of long COVID? What scientists know so far p.20

Researchers are trying to establish whether existing COVID-19 vaccines and treatments can prevent lasting symptoms.

doi: 10.1038/d41586-022-00823-y

Dozens of unidentified bat species probably live in Asia — and could host new viruses p.21

Study suggests some 40% of horseshoe bats in the region have yet to be formally described.

doi: 10.1038/d41586-022-00776-2

Could computer models be the key to better COVID vaccines? p.22

doi: 10.1038/d41586-022-00924-8

Why the WHO took two years to say COVID is airborne p.26

doi: 10.1038/d41586-022-00925-7

An added layer of repression for human genes p.41

A protein complex called the rixosome helps to degrade RNA transcripts that linger after gene expression ceases. This discovery points to distinct roles for the rixosome in regulating chromatin in different species.

doi: 10.1038/d41586-022-00519-3

Cryogenic mastery aids bid to spot elusive matter creation p.42

A cubic metre of tellurium held at cryogenic temperatures over many years has enabled a search for matter created in a rare nuclear process. The feat bodes well for stabilizing other complex systems at low temperatures.

doi: 10.1038/d41586-022-00836-7

Genome doubling causes double trouble p.44

Human cancer cells often double their genome through an error in cell division, and this can lead to further genomic instability. A detailed analysis of the first cell cycle after genome doubling sheds light on this phenomenon.

doi: 10.1038/d41586-022-00849-2

Twenty-five years of nanoscale thermodynamics p.46

A paper published in 1997 brought the thermodynamics of the nineteenth century into the twenty-first century — expanding the physics of transformations involved in the operation of steam engines to the realm of molecular motors.

doi: 10.1038/d41586-022-00869-y

Democratizing the mapping of gene mutations to protein biophysics p.47

A general method that quantifies and disentangles the effects of a gene’s mutations on the traits of its protein enables assessments of mutational effects on protein biophysics for many of the proteins of a living organism.

doi: 10.1038/d41586-022-00870-5

UV absorption by silicate cloud precursors in ultra-hot Jupiter WASP-178b p.49

doi: 10.1038/s41586-022-04453-2

Search for Majorana neutrinos exploiting millikelvin cryogenics with CUORE p.53

doi: 10.1038/s41586-022-04497-4

Charge-density-wave-driven electronic nematicity in a kagome superconductor p.59

doi: 10.1038/s41586-022-04493-8

Ultrathin ferroic HfO₂–ZrO₂ superlattice gate stack for advanced transistors p.65

doi: 10.1038/s41586-022-04425-6

Reconstructed covalent organic frameworks p.72

doi: 10.1038/s41586-022-04443-4

Autonomous fuelled directional rotation about a covalent single bond p.80

doi: 10.1038/s41586-022-04450-5

Multifunctional biocatalyst for conjugate reduction and reductive amination p.86

doi: 10.1038/s41586-022-04458-x

Automated iterative Csp3–C bond formation p.92

doi: 10.1038/s41586-022-04491-w

A stable hippocampal code in freely flying bats p.98

doi: 10.1038/s41586-022-04560-0

Entropy of city street networks linked to future spatial navigation ability p.104

doi: 10.1038/s41586-022-04486-7

Human distal lung maps and lineage hierarchies reveal a bipotent progenitor p.111

doi: 10.1038/s41586-022-04541-3

Human distal airways contain a multipotent secretory cell that can regenerate alveoli p.120

doi: 10.1038/s41586-022-04552-0

Plant phytochrome B is an asymmetric dimer with unique signalling potential p.127

doi: 10.1038/s41586-022-04529-z

Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2 p.134

doi: 10.1038/s41586-022-04482-x

Germinal centre-driven maturation of B cell response to mRNA vaccination p.141

doi: 10.1038/s41586-022-04527-1

Genetic instability from a single S phase after whole-genome duplication p.146

doi: 10.1038/s41586-022-04578-4

Crucial role and mechanism of transcription-coupled DNA repair in bacteria p.152

doi: 10.1038/s41586-022-04530-6

Targeting Xist with compounds that disrupt RNA structure and X inactivation p.160

doi: 10.1038/s41586-022-04537-z

Rixosomal RNA degradation contributes to silencing of Polycomb target genes p.167

doi: 10.1038/s41586-022-04598-0

Mapping the energetic and allosteric landscapes of protein binding domains p.175

doi: 10.1038/s41586-022-04586-4

Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3 p.184

doi: 10.1038/s41586-022-04467-w

Differential assembly diversifies GABAA receptor structures and signalling p.190

doi: 10.1038/s41586-022-04517-3

Structure, substrate recognition and initiation of hyaluronan synthase p.195

doi: 10.1038/s41586-022-04534-2