The alarming rise of complex genetic testing in human embryo selection p.549

Companies are marketing polygenic risk scores as part of IVF well ahead of a full understanding of the potential benefits — or dangers.

doi: 10.1038/d41586-022-00787-z

This is no time to stop tracking COVID-19 p.550

To live with the coronavirus, we cannot be blind to its movements.

doi: 10.1038/d41586-022-00788-y

Surge of HIV, tuberculosis and COVID feared amid war in Ukraine p.557

Infectious diseases are likely to spread as Russia’s invasion displaces people and disrupts health services.

doi: 10.1038/d41586-022-00748-6

Ukrainian researchers pressure journals to boycott Russian authors p.559

Most publications are still considering manuscripts irrespective of nationality — but Russia plans to remove a requirement for scientists to publish in foreign titles.

doi: 10.1038/d41586-022-00718-y

Chile’s science transformation gains steam with new president p.560

The liberal Gabriel Boric campaigned on a promise to invest in research and fight climate change, and has given scientists prominent positions in his administration.

doi: 10.1038/d41586-022-00696-1

China’s first Moon rocks ignite research bonanza p.561

Samples collected by Chang’e-5 are revealing exciting insights into the Moon’s evolution.

doi: 10.1038/d41586-022-00683-6

COVID’s true death toll: much higher than official records p.562

Modelling suggests that by the end of 2021, some 18 million people had died because of the pandemic.

doi: 10.1038/d41586-022-00708-0

COVID restrictions are lifting — what scientists think p.563

Many countries have started relaxing rules and scaling back testing. Researchers are divided over whether this return to normality is too fast, too soon.

doi: 10.1038/d41586-022-00620-7

Lessons from the COVID data wizards p.564

doi: 10.1038/d41586-022-00792-2

The rise of citational justice: how scholars are making references fairer p.568

doi: 10.1038/d41586-022-00793-1

Trade-offs between stability and manoeuvrability in bird flight p.579

An understanding of how wing shape affects a bird’s agility requires parameters relating mass and geometry to aerodynamic performance. Analysis of one aspect of flight, inertial characteristics, fills a gap in our knowledge.

doi: 10.1038/d41586-022-00638-x

A stellar clock reveals the assembly history of the Milky Way p.580

A brief stage in stellar evolution offers a precise means of dating stars in the Milky Way. The ages, compositions and motions of these stars all pinpoint the dynamical processes involved in the Galaxy’s formation.

doi: 10.1038/d41586-022-00768-2

Immune cells alter genetic decoding in cancer p.582

Cancer cells make proteins in which the amino acid phenylalanine is swapped for tryptophan when immune cells trigger a tryptophan shortage. This finding reveals unexpected dynamics of genetic decoding.

doi: 10.1038/d41586-022-00637-y

Promising reversible protein inhibitors kept on target p.583

Compounds that form reversible covalent bonds with lysine amino-acid residues in proteins have high potential for drug discovery. A chemical group has been reported that prolongs the time for which such compounds bind to their targets.

doi: 10.1038/d41586-022-00692-5

A smart sensor that can be woven into everyday life p.585

A hybrid design combines sensitivity and flexibility to create an acoustic single-fibre sensor that can be knitted into fabric. The future of tracking our health and fitness looks wearable — and perhaps even implantable.

doi: 10.1038/d41586-022-00691-6

Human genetic and immunological determinants of critical COVID-19 pneumonia p.587

doi: 10.1038/s41586-022-04447-0

A time-resolved picture of our Milky Way’s early formation history p.599

doi: 10.1038/s41586-022-04496-5

Optimal metrology with programmable quantum sensors p.604

doi: 10.1038/s41586-022-04435-4

Emergence of Fermi arcs due to magnetic splitting in an antiferromagnet p.610

doi: 10.1038/s41586-022-04412-x

Single fibre enables acoustic fabrics via nanometre-scale vibrations p.616

doi: 10.1038/s41586-022-04476-9

High-brightness all-polymer stretchable LED with charge-trapping dilution p.624

doi: 10.1038/s41586-022-04400-1

Metastable hexagonal close-packed palladium hydride in liquid cell TEM p.631

doi: 10.1038/s41586-021-04391-5

Boron clusters as broadband membrane carriers p.637

doi: 10.1038/s41586-022-04413-w

Geophysical imaging of the Yellowstone hydrothermal plumbing system p.643

doi: 10.1038/s41586-021-04379-1

Birds can transition between stable and unstable states via wing morphing p.648

doi: 10.1038/s41586-022-04477-8

Reproducible brain-wide association studies require thousands of individuals p.654

doi: 10.1038/s41586-022-04492-9

Frontal neurons driving competitive behaviour and ecology of social groups p.661

doi: 10.1038/s41586-021-04000-5

Cortical ensembles orchestrate social competition through hypothalamic outputs p.667

doi: 10.1038/s41586-022-04507-5

Immune regulation by fungal strain diversity in inflammatory bowel disease p.672

doi: 10.1038/s41586-022-04502-w

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa p.679

doi: 10.1038/s41586-022-04411-y

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters p.687

doi: 10.1038/s41586-022-04441-6

Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron p.693

doi: 10.1038/s41586-022-04442-5

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant p.700

doi: 10.1038/s41586-022-04462-1

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity p.706

doi: 10.1038/s41586-022-04474-x

SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo p.715

doi: 10.1038/s41586-022-04479-6

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants p.721

doi: 10.1038/s41586-022-04499-2

A genome-scale screen for synthetic drivers of T cell proliferation p.728

doi: 10.1038/s41586-022-04494-7

Regulation of liver subcellular architecture controls metabolic homeostasis p.736

doi: 10.1038/s41586-022-04488-5

Activation mechanism of the class D fungal GPCR dimer Ste2 p.743

doi: 10.1038/s41586-022-04498-3