India’s tech innovation engines must raise their game p.483

The number of prestigious Indian Institutes of Technology trebled in the space of a decade. But new arrivals are struggling to establish themselves and must quickly turn things around.

doi: 10.1038/d41586-022-00154-y

NASA’s Webb telescope is an initial success — despite formidable odds p.484

Science stands to make huge gains from the James Webb Space Telescope, but there are also lessons to learn from the epic management failures that beset the project.

doi: 10.1038/d41586-022-00153-z

Has Biden followed the science? What researchers say p.491

As the US president’s first year in office ends, Nature assesses whether he’s kept his promise to make evidence-based decisions.

doi: 10.1038/d41586-022-00108-4

What Charles Lieber’s conviction means for science p.493

After Harvard chemist’s trial, scientists report ripple effects for federal funding and research itself.

doi: 10.1038/d41586-022-00107-5

Webb telescope reaches its final destination far from Earth p.495

The ambitious observatory has arrived at its home — near a gravitationally special spot called L2 — for a premier view of the Universe.

doi: 10.1038/d41586-022-00128-0

Why scientists are racing to develop more COVID antivirals p.496

The first crop of antivirals against SARS-CoV-2 is promising. But new drugs will be needed to counter the looming threat of resistance.

doi: 10.1038/d41586-022-00112-8

Tonga volcano eruption created puzzling ripples in Earth’s atmosphere p.497

Powerful waves ringing through the atmosphere after the eruption of Hunga Tonga–Hunga Haʻapai are unlike anything seen before.

doi: 10.1038/d41586-022-00127-1

Did a mega drought topple empires 4,200 years ago? p.498

doi: 10.1038/d41586-022-00157-9

Hot surfaces cooled by isolating steam from spray p.509

An innovative microstructure design distributes water to rapidly cool a hot surface without interference from the steam that is created in the process. This approach could enable safer and more efficient power generation.

doi: 10.1038/d41586-022-00123-5

A grave matter of ancient kinship in Neolithic Britain p.510

An investigation into the nature of genetic connections between individuals interred in the same chambers of an ancient tomb in Britain about 5,700 years ago sheds light on kinship in an early society.

doi: 10.1038/d41586-021-03799-3

Bronze Age genomes reveal migration to Britain p.512

The genomes of hundreds of individuals who lived in Great Britain and in continental Europe during the Bronze Age provide evidence for a migration of people from the continent to southern Britain between 1000 and 875 bc.

doi: 10.1038/d41586-021-03770-2

Self-heating plasmas offer hope for energy from fusion p.514

Experiments have validated a way of producing nuclear energy known as laser-driven fusion, in which a plasma is heated and compressed. The milestone offers crucial evidence that the plasma can supply its own heat.

doi: 10.1038/d41586-022-00124-4

Cardiovascular diseases disrupt the bone-marrow niche p.515

The production of blood cells, including some immune cells, relies heavily on the bone-marrow microenvironment. Cardiovascular diseases are now found to corrupt this niche, leading to imbalances in blood-cell production.

doi: 10.1038/d41586-021-03550-y

The challenges and opportunities of battery-powered flight p.519

doi: 10.1038/s41586-021-04139-1

A radio transient with unusually slow periodic emission p.526

doi: 10.1038/s41586-021-04272-x

Time-crystalline eigenstate order on a quantum processor p.531

doi: 10.1038/s41586-021-04257-w

Quantum register of fermion pairs p.537

doi: 10.1038/s41586-021-04205-8

Burning plasma achieved in inertial fusion p.542

doi: 10.1038/s41586-021-04281-w

Deep physical neural networks trained with backpropagation p.549

doi: 10.1038/s41586-021-04223-6

Emergent interface vibrational structure of oxide superlattices p.556

doi: 10.1038/s41586-021-04238-z

d-wave superconductor" rel="external">Unconventional spectral signature of Tc in a pure d-wave superconductor p.562

doi: 10.1038/s41586-021-04251-2

Inhibiting the Leidenfrost effect above 1,000 °C for sustained thermal cooling p.568

doi: 10.1038/s41586-021-04307-3

Centimetre-scale perovskite solar cells with fill factors of more than 86 per cent p.573

doi: 10.1038/s41586-021-04216-5

Age of the oldest known Homo sapiens from eastern Africa p.579

doi: 10.1038/s41586-021-04275-8

A high-resolution picture of kinship practices in an Early Neolithic tomb p.584

doi: 10.1038/s41586-021-04241-4

Large-scale migration into Britain during the Middle to Late Bronze Age p.588

doi: 10.1038/s41586-021-04287-4

Spatial maps in piriform cortex during olfactory navigation p.595

doi: 10.1038/s41586-021-04242-3

Human blastoids model blastocyst development and implantation p.600

doi: 10.1038/s41586-021-04267-8

A naturally inspired antibiotic to target multidrug-resistant pathogens p.606

doi: 10.1038/s41586-021-04264-x

Long-acting capsid inhibitor protects macaques from repeat SHIV challenges p.612

doi: 10.1038/s41586-021-04279-4

A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity p.617

doi: 10.1038/s41586-021-04232-5

Multi-omic machine learning predictor of breast cancer therapy response p.623

doi: 10.1038/s41586-021-04278-5

Decoding gene regulation in the fly brain p.630

doi: 10.1038/s41586-021-04262-z

Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasis p.637

doi: 10.1038/s41586-021-04295-4

Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs p.643

doi: 10.1038/s41586-021-04274-9

Architecture of the chloroplast PSI–NDH supercomplex in Hordeum vulgare p.649

doi: 10.1038/s41586-021-04277-6