Artificial intelligence in structural biology is here to stay p.625

Machine learning will transform our understanding of protein folding. And it’s essential that all data be open.

doi: 10.1038/d41586-021-02037-0

The lack of people of colour in science images must be fixed p.626

Archives, libraries, photo agencies and publishers need to do better to reflect science’s true past and present.

doi: 10.1038/d41586-021-02036-1

The US is boosting funding for research monkeys in the wake of COVID p.633

The investments are promising but won’t fix the primate shortage, experts say.

doi: 10.1038/d41586-021-01894-z

DeepMind’s AI predicts structures for a vast trove of proteins p.635

AlphaFold neural network produced a ‘totally transformative’ database of more than 350,000 structures from Homo sapiens and 20 model organisms.

doi: 10.1038/d41586-021-02025-4

Massive DNA ‘Borg’ structures perplex scientists p.636

Researchers say they have discovered unique and exciting DNA strands in the mud — others aren’t sure of their novelty.

doi: 10.1038/d41586-021-01947-3

China launches world’s largest carbon market: but is it ambitious enough? p.637

Experts welcome the trading scheme, but question whether it is up to the task of helping China achieve its climate goals.

doi: 10.1038/d41586-021-01989-7

Should children get COVID vaccines? What the science says p.638

doi: 10.1038/d41586-021-01898-9

Deaths from COVID ‘incredibly rare’ among children p.639

Studies find that overall risk of death or severe disease from COVID-19 is very low in kids.

doi: 10.1038/d41586-021-01897-w

How the coronavirus infects cells — and why Delta is so dangerous p.640

doi: 10.1038/d41586-021-02039-y

A protective signal between the brain’s supporting cells in Alzheimer’s disease p.651

In a mouse model of Alzheimer’s disease, interleukin-3 protein released by cells called astrocytes activates microglia, the immune cells of the brain. These then cluster around disease-associated protein aggregates and help to clear them.

doi: 10.1038/d41586-021-01870-7

Direct installation of boron groups offers boost to medicinal chemistry p.652

Compounds called borylated azines have untapped potential for organic synthesis, but have faced problems associated with their preparation, stability and reactivity. A new class of these compounds provides a solution.

doi: 10.1038/d41586-021-02007-6

Sperm CatSper ion channel swims into sharper focus p.654

Activation of the CatSper membrane ion channel triggers enhanced sperm motility, and this protein complex is required for male fertility. Structural data now provide insights into the channel, and offer a few surprises, too.

doi: 10.1038/d41586-021-01945-5

Earthquakes triggered by underground fluid injection modelled for a tectonically active oil field p.655

An analysis of the Val d’Agri oil field in Italy provides insight into how processes associated with wastewater disposal trigger earthquakes — and how such effects can be reduced to maintain the economic viability of mature oil fields.

doi: 10.1038/d41586-021-01997-7

Light bending and X-ray echoes from behind a supermassive black hole p.657

doi: 10.1038/s41586-021-03667-0

Incoherent transport across the strange-metal regime of overdoped cuprates p.661

doi: 10.1038/s41586-021-03622-z

Linear-in temperature resistivity from an isotropic Planckian scattering rate p.667

doi: 10.1038/s41586-021-03697-8

Spectroscopic evidence for a gold-coloured metallic water solution p.673

doi: 10.1038/s41586-021-03646-5

A radical approach for the selective C–H borylation of azines p.677

doi: 10.1038/s41586-021-03637-6

A process-based approach to understanding and managing triggered seismicity p.684

doi: 10.1038/s41586-021-03668-z

Dynamical prefrontal population coding during defensive behaviours p.690

doi: 10.1038/s41586-021-03726-6

Food cue regulation of AGRP hunger neurons guides learning p.695

doi: 10.1038/s41586-021-03729-3

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease p.701

doi: 10.1038/s41586-021-03734-6

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020 p.707

doi: 10.1038/s41586-021-03677-y

Untangling introductions and persistence in COVID-19 resurgence in Europe p.713

doi: 10.1038/s41586-021-03754-2

Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants p.718

doi: 10.1038/s41586-021-03673-2

Metabolic control of T_FH cells and humoral immunity by phosphatidylethanolamine p.724

doi: 10.1038/s41586-021-03692-z

EGFR activation limits the response of liver cancer to lenvatinib p.730

doi: 10.1038/s41586-021-03741-7

Enhancer release and retargeting activates disease-susceptibility genes p.735

doi: 10.1038/s41586-021-03577-1

Structural basis of early translocation events on the ribosome p.741

doi: 10.1038/s41586-021-03713-x

Structure of a mammalian sperm cation channel complex p.746

doi: 10.1038/s41586-021-03742-6