The world’s largest radio telescope should open its skies to all p.527

The Square Kilometre Array must invite the best ideas from around the globe to help it probe astronomy’s deepest questions.

doi: 10.1038/d41586-021-00468-3

Collaborations with artists go beyond communicating the science p.528

Scientists and artists are working together as never before, finds a Nature poll. Both sides need to invest time, and embrace surprise and challenge.

doi: 10.1038/d41586-021-00469-2

Touch down! NASA’s Mars landing sparks new era of exploration p.535

Having stuck its nail-biting landing, the Perseverance rover will now collect rocks to return to Earth and record Mars sounds for the first time.

doi: 10.1038/d41586-021-00432-1

Million-year-old mammoth genomes shatter record for oldest ancient DNA p.537

Permafrost-preserved teeth, up to 1.6 million years old, identify a new kind of mammoth in Siberia.

doi: 10.1038/d41586-021-00436-x

COVID vaccines and safety: what the research says p.538

doi: 10.1038/d41586-021-00290-x

Quantum network is step towards ultrasecure internet p.540

Experiment connects three devices with entangled photons, demonstrating a key technique that could enable a future quantum internet.

doi: 10.1038/d41586-021-00420-5

Give African research participants more say in genomic data, say scientists p.542

Tensions are building in Africa over the rules that govern the donation of biological samples and data to research.

doi: 10.1038/d41586-021-00400-9

Superspreading drives the COVID pandemic — and could help to tame it p.544

doi: 10.1038/d41586-021-00460-x

Signs of self-sustained inflammatory circuits in severe COVID pneumonia p.553

Pneumonia is a hallmark of severe COVID-19, but many details about the lung inflammation observed in this disease are unknown. An analysis of cells from the lungs of people with this condition sheds some light on the mystery.

doi: 10.1038/d41586-021-00296-5

Cells use loop extrusion to weave and tie the genome p.554

A study reveals that a process called loop extrusion, which is central to the folding and function of chromosomes, also seems to play a key part in the repair of double-strand DNA breaks.

doi: 10.1038/d41586-021-00351-1

Accelerator-based light sources get a boost p.556

The structure of matter can be explored using the light emitted by particle accelerators. An experiment demonstrates how the properties of two such light sources — synchrotrons and free-electron lasers — can be combined.

doi: 10.1038/d41586-021-00431-2

Mutation alters chromatin changes during injury response to drive cancer p.557

Cancer-associated mutations promote the formation of pancreatic tumours after tissue injury, but how this occurs is unclear. Changes to chromatin in injured cells with such mutations explain this predisposition to malignancy.

doi: 10.1038/d41586-021-00211-y

Antimatter in the proton is more down than up p.559

Protons are found in all atoms, so it might be surprising to learn that they contain antimatter. It now emerges that there is an imbalance in the types of antimatter in the proton — a finding for which there is no agreed theoretical explanation.

doi: 10.1038/d41586-021-00430-3

The asymmetry of antimatter in the proton p.561

doi: 10.1038/s41586-021-03282-z

Angular momentum generation in nuclear fission p.566

doi: 10.1038/s41586-021-03304-w

Deterministic multi-qubit entanglement in a quantum network p.571

doi: 10.1038/s41586-021-03288-7

Experimental demonstration of the mechanism of steady-state microbunching p.576

doi: 10.1038/s41586-021-03203-0

First return, then explore p.580

doi: 10.1038/s41586-020-03157-9

Efficient perovskite solar cells via improved carrier management p.587

doi: 10.1038/s41586-021-03285-w

Strong tough hydrogels via the synergy of freeze-casting and salting out p.594

doi: 10.1038/s41586-021-03212-z

Genomic basis of geographical adaptation to soil nitrogen in rice p.600

doi: 10.1038/s41586-020-03091-w

Evolving schema representations in orbitofrontal ensembles during learning p.606

doi: 10.1038/s41586-020-03061-2

Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis p.612

doi: 10.1038/s41586-020-03060-3

Cooperative epithelial phagocytosis enables error correction in the early embryo p.618

doi: 10.1038/s41586-021-03200-3

The Card1 nuclease provides defence during type III CRISPR immunity p.624

Structural analyses of the type III CRISPR accessory protein Card1, which induces dormancy in infected hosts to provide immunity against phage infection, reveal the mechanisms by which it cleaves single-stranded RNA and DNA.

doi: 10.1038/s41586-021-03206-x

Correlates of protection against SARS-CoV-2 in rhesus macaques p.630

doi: 10.1038/s41586-020-03041-6

Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia p.635

doi: 10.1038/s41586-020-03148-w

A gene–environment-induced epigenetic program initiates tumorigenesis p.642

doi: 10.1038/s41586-020-03147-x

Spatiotemporal dissection of the cell cycle with single-cell proteogenomics p.649

doi: 10.1038/s41586-021-03232-9

Tracking break-induced replication shows that it stalls at roadblocks p.655

doi: 10.1038/s41586-020-03172-w

Loop extrusion as a mechanism for formation of DNA damage repair foci p.660

doi: 10.1038/s41586-021-03193-z

Functional refolding of the penetration protein on a non-enveloped virus p.666

doi: 10.1038/s41586-020-03124-4

Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly p.671

doi: 10.1038/s41586-021-03197-9