COVID vaccines: the world’s medical regulators need access to open data p.195

The global race to produce COVID vaccines is a chance for regulators and drug companies to create a more harmonized approvals process.

doi: 10.1038/d41586-020-03458-z

Accounting for sex and gender makes for better science p.196

The European Commission is set to insist on steps that will make research design more inclusive.

doi: 10.1038/d41586-020-03459-y

‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures p.203

Google’s deep-learning program for determining the 3D shapes of proteins stands to transform biology, say scientists.

doi: 10.1038/d41586-020-03348-4

The UK has approved a COVID vaccine — here’s what scientists now want to know p.205

doi: 10.1038/d41586-020-03441-8

Can Joe Biden make good on his revolutionary climate agenda? p.206

Although he faces a split Congress, the US president-elect has levers he can pull in the government to advance clean energy and curb global warming.

doi: 10.1038/d41586-020-03250-z

Meet the scientists investigating the origins of the COVID pandemic p.207

Ten researchers with expertise in virology, public health and animals will seek to answer this key question.

doi: 10.1038/d41586-020-03402-1

Reversal of biological clock restores vision in old mice p.208

‘Reprogramming’ approach seems to make old cells young again.

doi: 10.1038/d41586-020-03403-0

The researcher fighting to embed analysis of sex and gender into science p.209

doi: 10.1038/d41586-020-03336-8

How the first life on Earth survived its biggest threat — water p.210

doi: 10.1038/d41586-020-03461-4

The changing face of birds from the age of the dinosaurs p.221

The fossil record traces the origin of the modern bird skull as birds evolved from their dinosaurian ancestors. Now the discovery of a bizarre fossil reveals a surprising diversion during this process of facial transformation.

doi: 10.1038/d41586-020-03260-x

Proton collisions probe the final frontier of the standard model of particle physics p.222

The nuclear forces that act on short-lived subatomic particles have been hard to study. This problem has now been solved by smashing high-energy protons together and measuring the momenta of the unstable particles produced.

doi: 10.1038/d41586-020-03393-z

Cracking the cell access code for the deadly virus VEEV p.223

The discovery that the receptor protein LDLRAD3 is essential for infection of human cells by Venezuelan equine encephalitis virus could inform strategies to combat this potentially lethal infection.

doi: 10.1038/d41586-020-03192-6

Trade-offs for equitable climate policy assessed p.225

Computational models show that regionally varied prices for carbon emissions can greatly reduce the need for poor countries to receive financial assistance to tackle climate change, while still stabilizing global warming.

doi: 10.1038/d41586-020-03392-0

Detection of large-scale X-ray bubbles in the Milky Way halo p.227

doi: 10.1038/s41586-020-2979-0

Unveiling the strong interaction among hadrons at the LHC p.232

doi: 10.1038/s41586-020-3001-6

Dipolar evaporation of reactive molecules to below the Fermi temperature p.239

doi: 10.1038/s41586-020-2980-7

Operation of an optical atomic clock with a Brillouin laser subsystem p.244

doi: 10.1038/s41586-020-2981-6

Capillary condensation under atomic-scale confinement p.250

doi: 10.1038/s41586-020-2978-1

Catalytic asymmetric addition of an amine N–H bond across internal alkenes p.254

doi: 10.1038/s41586-020-2919-z

Quantification of an efficiency–sovereignty trade-off in climate policy p.261

An integrated assessment model analysis shows that a moderately differentiated carbon price could achieve as much climate mitigation as a uniform carbon tax, avoiding concerns regarding equity between participating countries or sovereignty.

doi: 10.1038/s41586-020-2982-5

Clustered versus catastrophic global vertebrate declines p.267

doi: 10.1038/s41586-020-2920-6

Late Cretaceous bird from Madagascar reveals unique development of beaks p.272

doi: 10.1038/s41586-020-2945-x

Multiple wheat genomes reveal global variation in modern breeding p.277

doi: 10.1038/s41586-020-2961-x

The barley pan-genome reveals the hidden legacy of mutation breeding p.284

doi: 10.1038/s41586-020-2947-8

PIEZO2 in sensory neurons and urothelial cells coordinates urination p.290

doi: 10.1038/s41586-020-2830-7

Chemico-genetic discovery of astrocytic control of inhibition in vivo p.296

doi: 10.1038/s41586-020-2926-0

The gut microbiota is associated with immune cell dynamics in humans p.303

doi: 10.1038/s41586-020-2971-8

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus p.308

doi: 10.1038/s41586-020-2915-3

Sex differences in immune responses that underlie COVID-19 disease outcomes p.315

doi: 10.1038/s41586-020-2700-3

Tunable dynamics of B cell selection in gut germinal centres p.321

Antibody selection and maturation within B cells found in gut-associated germinal centres is stimulated by the gut microbiota, to a degree that depends on the presence and composition of the microbes.

doi: 10.1038/s41586-020-2865-9

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion p.327

doi: 10.1038/s41586-020-2772-0

A metastasis map of human cancer cell lines p.331

doi: 10.1038/s41586-020-2969-2

A map of cis-regulatory elements and 3D genome structures in zebrafish p.337

doi: 10.1038/s41586-020-2962-9

Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction p.344

doi: 10.1038/s41586-020-2673-2

Structures and pH-sensing mechanism of the proton-activated chloride channel p.350

doi: 10.1038/s41586-020-2875-7