Arctic science cannot afford a new cold war p.7

doi: 10.1038/d41586-020-02739-x

COVID vaccine confidence requires radical transparency p.8

Public trust in a potential vaccine is under threat. Drug companies and their academic partners must disclose protocols and results data.

doi: 10.1038/d41586-020-02738-y

The US National Academy of Sciences can now kick out harassers. So why hasn’t it? p.15

The NAS told Nature that no one has used the complaint system put in place last year, even though several academy members are known sexual harassers.

doi: 10.1038/d41586-020-02640-7

COVID-vaccine results are on the way — and scientists’ concerns are growing p.16

Researchers warn that vaccines could stumble on safety trials, be fast-tracked because of politics or fail to meet the public’s expectations.

doi: 10.1038/d41586-020-02706-6

The first-ever image of a black hole is now a movie p.18

Pictures created from old observations show the void’s stormy evolution over the past decade.

doi: 10.1038/d41586-020-02717-3

Censored: Australian scientists say suppression of environment research is getting worse p.19

Survey finds that many researchers are banned from speaking about their work or have had their research altered to downplay risks.

doi: 10.1038/d41586-020-02669-8

‘Apocalyptic’ fires are ravaging the world’s largest tropical wetland p.20

Infernos in South America’s Pantanal region have burnt twice the area of California’s fires this year. Researchers fear the rare ecosystem will never recover.

doi: 10.1038/d41586-020-02716-4

Alexa, do I have COVID-19? p.22

doi: 10.1038/d41586-020-02732-4

The worst is yet to come for the Greenland ice sheet p.29

doi: 10.1038/d41586-020-02700-y

The brain rhythms that detach us from reality p.31

The rhythmic activity of a single layer of neurons has now been shown to cause dissociation — an experience involving a feeling of disconnection from the surrounding world.

doi: 10.1038/d41586-020-02505-z

Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance p.32

An ancient resistance mechanism poses a problem when using streptogramin antibiotics. A modular approach to drug synthesis exploits this same mechanism to generate an antibiotic that avoids the emergence of resistance.

doi: 10.1038/d41586-020-02565-1

Both naive and memory B cells respond to flu vaccine p.34

Influenza vaccination induces a protective memory immune response. The finding that human naive and memory B cells enter vaccine-induced germinal-centre structures suggests that both cell types aid this memory response.

doi: 10.1038/d41586-020-02556-2

Fractional antiferromagnetic skyrmion lattice induced by anisotropic couplings p.37

doi: 10.1038/s41586-020-2716-8

Graphene-based Josephson junction microwave bolometer p.42

doi: 10.1038/s41586-020-2752-4

Bolometer operating at the threshold for circuit quantum electrodynamics p.47

doi: 10.1038/s41586-020-2753-3

Active particles induce large shape deformations in giant lipid vesicles p.52

doi: 10.1038/s41586-020-2730-x

Concentric liquid reactors for chemical synthesis and separation p.57

doi: 10.1038/s41586-020-2768-9

An enzymatic Alder-ene reaction p.64

doi: 10.1038/s41586-020-2743-5

Rate of mass loss from the Greenland Ice Sheet will exceed Holocene values this century p.70

doi: 10.1038/s41586-020-2742-6

The ecological and genomic basis of explosive adaptive radiation p.75

doi: 10.1038/s41586-020-2652-7

Genome-wide detection of tandem DNA repeats that are expanded in autism p.80

doi: 10.1038/s41586-020-2579-z

Deep posteromedial cortical rhythm in dissociation p.87

doi: 10.1038/s41586-020-2731-9

Shared yet dissociable neural codes across eye gaze, valence and expectation p.95

doi: 10.1038/s41586-020-2740-8

Reprogramming roadmap reveals route to human induced trophoblast stem cells p.101

doi: 10.1038/s41586-020-2734-6

Microbiota-derived metabolite promotes HDAC3 activity in the gut p.108

doi: 10.1038/s41586-020-2604-2

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing p.113

doi: 10.1038/s41586-020-2577-1

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells p.120

doi: 10.1038/s41586-020-2746-2

Human germinal centres engage memory and naive B cells after influenza vaccination p.127

doi: 10.1038/s41586-020-2711-0

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic p.133

doi: 10.1038/s41586-020-2541-0

Conformation of sister chromatids in the replicated human genome p.139

doi: 10.1038/s41586-020-2744-4

Synthetic group A streptogramin antibiotics that overcome Vat resistance p.145

doi: 10.1038/s41586-020-2761-3

Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B p.151

doi: 10.1038/s41586-020-2747-1