Fewer than 20 extinctions a year: does the world need a single target for biodiversity? p.7

A proposal for one, simple goal, equivalent to the 2 °C climate target, needs to be thoroughly assessed.

doi: 10.1038/d41586-020-01936-y

How Europe can fix its forests data gap p.8

doi: 10.1038/d41586-020-01848-x

Mini organs reveal how the coronavirus ravages the body p.15

The virus can damage lung, liver and kidney tissue grown in the lab, which might explain some severe COVID-19 complications in people.

doi: 10.1038/d41586-020-01864-x

Mounting clues suggest the coronavirus might trigger diabetes p.16

Evidence from tissue studies and some people with COVID-19 shows that the virus damages insulin-producing cells.

doi: 10.1038/d41586-020-01891-8

CRISPR gene editing in human embryos wreaks chromosomal mayhem p.17

Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing.

doi: 10.1038/d41586-020-01906-4

Trump to suspend new visas for foreign scholars p.19

Latest action sows anxiety and confusion across the US scientific workforce.

doi: 10.1038/d41586-020-01885-6

Neutrinos reveal final secret of Sun’s nuclear fusion p.20

Detection of particles produced by the Sun’s core supports long-held theory about how our star is powered.

doi: 10.1038/d41586-020-01908-2

NIH’s new sexual-harassment rules are still too weak, say critics p.21

The agency has outlined actions it may take to deal with bullies and harassers, but it still relies on universities to report bad behaviour.

doi: 10.1038/d41586-020-01921-5

What the data say about police brutality and racial bias — and which reforms might work p.22

doi: 10.1038/d41586-020-01846-z

Quantum fluctuations have been shown to affect macroscopic objects p.31

doi: 10.1038/d41586-020-01914-4

Neutrophil ‘safety net’ causes cancer cells to metastasize and proliferate p.32

Immune cells called neutrophils can support the spread of cancer. How neutrophils aid this process now comes into focus through insights into the function of structures called neutrophil extracellular traps.

doi: 10.1038/d41586-020-01672-3

Flipping the switch on the body’s thermoregulatory system p.34

A population of excitatory neurons has been found to have a key role in controlling body temperature in rodents. The discovery adds to a body of work that is raising questions about long-standing models of thermoregulation.

doi: 10.1038/d41586-020-01600-5

Atomic forces mapped out by lasers p.35

doi: 10.1038/d41586-020-01913-5

T cells engineered to target senescence p.37

Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options.

doi: 10.1038/d41586-020-01759-x

A remnant planetary core in the hot-Neptune desert p.39

doi: 10.1038/s41586-020-2421-7

Quantum correlations between light and the kilogram-mass mirrors of LIGO p.43

doi: 10.1038/s41586-020-2420-8

Fluorescent bicolour sensor for low-background neutrinoless double β decay experiments p.48

doi: 10.1038/s41586-020-2431-5

Laser picoscopy of valence electrons in solids p.55

doi: 10.1038/s41586-020-2429-z

Observation of branched flow of light p.60

doi: 10.1038/s41586-020-2376-8

Chemical gradients in human enamel crystallites p.66

doi: 10.1038/s41586-020-2433-3

Abrupt increase in harvested forest area over Europe after 2015 p.72

doi: 10.1038/s41586-020-2438-y

Revealing enigmatic mucus structures in the deep sea using DeepPIV p.78

doi: 10.1038/s41586-020-2345-2

Mapping and characterization of structural variation in 17,795 human genomes p.83

doi: 10.1038/s41586-020-2371-0

Whole-genome sequencing of a sporadic primary immunodeficiency cohort p.90

doi: 10.1038/s41586-020-2265-1

Whole-genome sequencing of patients with rare diseases in a national health system p.96

doi: 10.1038/s41586-020-2434-2

A map of object space in primate inferotemporal cortex p.103

doi: 10.1038/s41586-020-2350-5

A discrete neuronal circuit induces a hibernation-like state in rodents p.109

doi: 10.1038/s41586-020-2163-6

Neurons that regulate mouse torpor p.115

doi: 10.1038/s41586-020-2387-5

Hepatic NADH reductive stress underlies common variation in metabolic traits p.122

doi: 10.1038/s41586-020-2337-2

Senolytic CAR T cells reverse senescence-associated pathologies p.127

doi: 10.1038/s41586-020-2403-9

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25 p.133

doi: 10.1038/s41586-020-2394-6

Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA p.139

doi: 10.1038/s41586-020-2336-3

Electromechanical coupling in the hyperpolarization-activated K⁺ channel KAT1 p.145

doi: 10.1038/s41586-020-2335-4

Structural transitions in influenza haemagglutinin at membrane fusion pH p.150

doi: 10.1038/s41586-020-2333-6