As coronavirus spreads, the time to think about the next epidemic is now p.191

World leaders and international donors must strengthen the most vulnerable nations’ health-care systems.

doi: 10.1038/d41586-020-00379-9

Irreproducibility is not a sign of failure, but an inspiration for fresh ideas p.191

doi: 10.1038/d41586-020-00380-2

Combat burnout: respect the out-of-office message p.192

Employers must do more to support researchers when they take a break.

doi: 10.1038/d41586-020-00353-5

‘Avalanche’ of spider-paper retractions shakes behavioural-ecology community p.199

Allegations of fabricated data have prompted a university investigation and some soul-searching.

doi: 10.1038/d41586-020-00287-y

Highly cited researcher banned from journal board for citation abuse p.200

Investigation finds that biophysicist Kuo-Chen Chou repeatedly suggested dozens of citations be added to papers.

doi: 10.1038/d41586-020-00335-7

Revolutionary cryo-EM is taking over structural biology p.201

The number of protein structures being determined by cryo-electron microscopy is growing at an explosive rate.

doi: 10.1038/d41586-020-00341-9

The scientists restoring a gold-mining disaster zone in the Peruvian Amazon p.202

Months after the military expelled thousands of illegal miners from La Pampa, researchers gained access to a sandy wasteland.

doi: 10.1038/d41586-020-00119-z

How peat could protect the planet p.204

doi: 10.1038/d41586-020-00355-3

Quantum cascade laser lives on the edge p.219

doi: 10.1038/d41586-020-00323-x

Protein structure reveals how a malaria parasite imports a wide range of sugars p.220

Unlike many sugar-transporting proteins, a transporter in one species of malaria parasite can import several types of sugar equally effectively, aiding the parasite’s survival. The structure of this protein reveals the reason for its versatility.

doi: 10.1038/d41586-020-00148-8

Ordered absences observed in porous framework materials p.222

doi: 10.1038/d41586-020-00329-5

Neurodegenerative diseases distinguished through protein-structure analysis p.223

Parkinson’s disease and multiple system atrophy involve the protein α-synuclein. Proof that aggregated α-synuclein adopts a different structure in each case suggests that its conformation underlies the distinct disorders.

doi: 10.1038/d41586-020-00131-3

Smoke signals in the DNA of normal lung cells p.224

Healthy cells in smokers’ lungs have a high burden of mutations, similar to the mutational profile of lung cancer. Surprisingly, ex-smokers’ lungs have a large fraction of healthy cells with nearly normal profiles.

doi: 10.1038/d41586-020-00165-7

Scrutinizing the effects of digital technology on mental health p.226

Does time spent using digital technology and social media have an adverse effect on mental health, especially that of adolescents? Here, two scientists discuss the question, and how digital devices might be used to improve well-being.

doi: 10.1038/d41586-020-00296-x

The promise and challenge of therapeutic genome editing p.229

doi: 10.1038/s41586-020-1978-5

A Galactic-scale gas wave in the solar neighbourhood p.237

doi: 10.1038/s41586-019-1874-z

Entanglement of two quantum memories via fibres over dozens of kilometres p.240

doi: 10.1038/s41586-020-1976-7

Electrically pumped topological laser with valley edge modes p.246

doi: 10.1038/s41586-020-1981-x

Li metal deposition and stripping in a solid-state battery via Coble creep p.251

doi: 10.1038/s41586-020-1972-y

Hidden diversity of vacancy networks in Prussian blue analogues p.256

doi: 10.1038/s41586-020-1980-y

Premature mortality related to United States cross-state air pollution p.261

doi: 10.1038/s41586-020-1983-8

Tobacco smoking and somatic mutations in human bronchial epithelium p.266

doi: 10.1038/s41586-020-1961-1

Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy p.273

doi: 10.1038/s41586-020-1984-7

Live-animal imaging of native haematopoietic stem and progenitor cells p.278

doi: 10.1038/s41586-020-1971-z

Neuronal programming by microbiota regulates intestinal physiology p.284

doi: 10.1038/s41586-020-1975-8

The guidance receptor plexin D1 is a mechanosensor in endothelial cells p.290

doi: 10.1038/s41586-020-1979-4

Stress- and ubiquitylation-dependent phase separation of the proteasome p.296

doi: 10.1038/s41586-020-1982-9

Phase separation organizes the site of autophagosome formation p.301

doi: 10.1038/s41586-020-1977-6

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer p.306

doi: 10.1038/s41586-020-1930-8

Zucchini consensus motifs determine the mechanism of pre-piRNA production p.311

doi: 10.1038/s41586-020-1966-9

Processive extrusion of polypeptide loops by a Hsp100 disaggregase p.317

doi: 10.1038/s41586-020-1964-y

The molecular basis for sugar import in malaria parasites p.321

doi: 10.1038/s41586-020-1963-z