The trick that could inject new life into an old tuberculosis vaccine p.145

The BCG vaccine is nearing its centenary. A new delivery method could protect more people from one of the world’s biggest killers.

doi: 10.1038/d41586-020-00003-w

The huge scientific effort to study Notre-Dame’s ashes p.153

doi: 10.1038/d41586-020-00008-5

What CRISPR-baby prison sentences mean for research p.154

Chinese court sends strong signal by punishing He Jiankui and two colleagues.

doi: 10.1038/d41586-020-00001-y

How one astronomer hears the Universe p.155

doi: 10.1038/d41586-019-03938-x

Quest to use CRISPR against disease gains ground p.156

As the first clinical-trial results trickle in, researchers look ahead to more sophisticated medical applications for genome editing.

doi: 10.1038/d41586-019-03919-0

The quest to decipher how the body’s cells sense touch p.158

doi: 10.1038/d41586-019-03955-w

A structurally unstable semiconductor stabilized and enhanced by strain p.171

doi: 10.1038/d41586-019-03918-1

Long-term predator–prey cycles finally achieved in the lab p.172

A combination of laboratory experiments and mathematical and statistical analysis provides an affirmative answer to a decades-old question — can a predator and its prey coexist indefinitely?

doi: 10.1038/d41586-019-03603-3

The physics of ice skating p.173

The slipperiness of ice is poorly understood at a microscopic level. Experiments that probe how the surface of ice melts and flows in response to wear help to explain the exceptionally low friction that underpins winter sports.

doi: 10.1038/d41586-019-03833-5

Brain states behind exploring and hunting revealed p.175

The brain fluctuates between different internal states, each of which drives particular behaviours. Brain-wide imaging reveals the internal states that help zebrafish larvae to choose between exploring and hunting.

doi: 10.1038/d41586-019-03811-x

Not all fast radio bursts are created equal p.176

Astronomical signals called fast radio bursts remain enigmatic, but a key discovery has now been made. A second repeating fast radio burst has been traced to its host galaxy, and its home bears little resemblance to that of the first.

doi: 10.1038/d41586-019-03894-6

A brief history of human disease genetics p.179

doi: 10.1038/s41586-019-1879-7

A repeating fast radio burst source localized to a nearby spiral galaxy p.190

doi: 10.1038/s41586-019-1866-z

Resonant microwave-mediated interactions between distant electron spins p.195

doi: 10.1038/s41586-019-1867-y

Synthesis and properties of free-standing monolayer amorphous carbon p.199

doi: 10.1038/s41586-019-1871-2

Proton-assisted growth of ultra-flat graphene films p.204

doi: 10.1038/s41586-019-1870-3

Strain engineering and epitaxial stabilization of halide perovskites p.209

doi: 10.1038/s41586-019-1868-x

Single-chain heteropolymers transport protons selectively and rapidly p.216

doi: 10.1038/s41586-019-1881-0

Paleoclimate evidence of vulnerable permafrost during times of low sea ice p.221

doi: 10.1038/s41586-019-1880-1

Long-term cyclic persistence in an experimental predator–prey system p.226

doi: 10.1038/s41586-019-1857-0

Mapping child growth failure across low- and middle-income countries p.231

doi: 10.1038/s41586-019-1878-8

Mapping disparities in education across low- and middle-income countries p.235

doi: 10.1038/s41586-019-1872-1

Internal state dynamics shape brainwide activity and foraging behavior p.239

doi: 10.1038/s41586-019-1858-z

A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases p.244

doi: 10.1038/s41586-019-1786-y

IL-17a promotes sociability in mouse models of neurodevelopmental disorders p.249

doi: 10.1038/s41586-019-1843-6

Somatic inflammatory gene mutations in human ulcerative colitis epithelium p.254

doi: 10.1038/s41586-019-1844-5

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis p.260

doi: 10.1038/s41586-019-1856-1

HBO1 is required for the maintenance of leukaemia stem cells p.266

doi: 10.1038/s41586-019-1835-6

Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system p.271

doi: 10.1038/s41586-019-1849-0

Structure of the human metapneumovirus polymerase phosphoprotein complex p.275

doi: 10.1038/s41586-019-1759-1