A new look for Nature p.453

doi: 10.1038/d41586-019-03167-2

A precarious milestone for quantum computing p.453

doi: 10.1038/d41586-019-03168-1

Young universities show leadership p.454

doi: 10.1038/d41586-019-03166-3

Hello quantum world! Google publishes landmark quantum supremacy claim p.461

doi: 10.1038/d41586-019-03213-z

Earth scientists push ambitious project to map Canada’s geology p.463

A fleet of geophysical observatories would probe everything from the inner Earth to the upper atmosphere.

doi: 10.1038/d41586-019-03030-4

Super-precise new CRISPR tool could tackle a plethora of genetic diseases p.464

The system allows researchers more control over DNA changes, potentially opening up conditions that have challenged gene-editors.

doi: 10.1038/d41586-019-03164-5

Russian ‘CRISPR-baby’ scientist has started editing genes in human eggs with goal of altering deaf gene p.465

Denis Rebrikov also told Nature that he does not plan to implant gene-edited embryos until he gets regulatory approval.

doi: 10.1038/d41586-019-03018-0

How the earliest mammals thrived alongside dinosaurs p.468

doi: 10.1038/d41586-019-03170-7

Quantum computing takes flight p.487

A programmable quantum computer has been reported to outperform the most powerful conventional computers in a specific task — a milestone in computing comparable in importance to the Wright brothers’ first flights.

doi: 10.1038/d41586-019-03173-4

Gut microbes regulate neurons to help mice forget their fear p.488

doi: 10.1038/d41586-019-03114-1

A fresh mechanism for how buckyballs form in space p.490

The spectroscopic fingerprints of buckyballs have been observed in space, but questions remain about how these large molecules form. Laboratory experiments have revealed a possible mechanism.

doi: 10.1038/d41586-019-03139-6

Light trapping gets a boost p.491

doi: 10.1038/d41586-019-03143-w

Histone lactylation links metabolism and gene regulation p.492

doi: 10.1038/d41586-019-03122-1

Early tetrapods had an eye on the land p.494

doi: 10.1038/d41586-019-03107-0

Identification of strontium in the merger of two neutron stars p.497

doi: 10.1038/s41586-019-1676-3

Topologically enabled ultrahigh-Q guided resonances robust to out-of-plane scattering p.501

doi: 10.1038/s41586-019-1664-7

Quantum supremacy using a programmable superconducting processor p.505

doi: 10.1038/s41586-019-1666-5

An antiaromatic-walled nanospace p.511

doi: 10.1038/s41586-019-1661-x

Site-specific allylic C–H bond functionalization with a copper-bound N-centred radical p.516

doi: 10.1038/s41586-019-1655-8

Similar scaling laws for earthquakes and Cascadia slow-slip events p.522

doi: 10.1038/s41586-019-1673-6

Morphology of the earliest reconstructable tetrapod Parmastega aelidae p.527

doi: 10.1038/s41586-019-1636-y

The landscape of somatic mutation in normal colorectal epithelial cells p.532

doi: 10.1038/s41586-019-1672-7

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver p.538

doi: 10.1038/s41586-019-1670-9

The microbiota regulate neuronal function and fear extinction learning p.543

doi: 10.1038/s41586-019-1644-y

Bacterial biodiversity drives the evolution of CRISPR-based phage resistance p.549

doi: 10.1038/s41586-019-1662-9

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing p.553

doi: 10.1038/s41586-019-1658-5

A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila p.559

doi: 10.1038/s41586-019-1675-4

VISTA is an acidic pH-selective ligand for PSGL-1 p.565

doi: 10.1038/s41586-019-1674-5

Stabilization of chromatin topology safeguards genome integrity p.571

doi: 10.1038/s41586-019-1659-4

Metabolic regulation of gene expression by histone lactylation p.575

doi: 10.1038/s41586-019-1678-1

Structural basis of species-selective antagonist binding to the succinate receptor p.581

doi: 10.1038/s41586-019-1663-8