A stem-cell race that no one wins p.463

doi: 10.1038/d41586-019-02844-6

The value of biodiversity is not the same as its price p.463

doi: 10.1038/d41586-019-02882-0

We ignore the past at our peril p.464

To navigate the present, we must heed the lessons of history.

doi: 10.1038/d41586-019-02845-5

Why young climate activists have captured the world’s attention p.471

doi: 10.1038/d41586-019-02696-0

Scientists worldwide join strikes for climate change p.472

From Bangkok to Brisbane, researchers were among those protesting to urge action on global warming.

doi: 10.1038/d41586-019-02791-2

Trapped: why 300 scientists are locking themselves in Arctic ice p.473

For one year, a research ship will drift while frozen in sea ice — and give scientists their closest look at the rapid changes gripping the polar north.

doi: 10.1038/d41586-019-02823-x

China’s tree-planting drive could falter in a warming world p.474

Researchers warn that the country’s push to hold back its deserts could strain water resources.

doi: 10.1038/d41586-019-02789-w

First portrait of mysterious Denisovans drawn from DNA p.475

Scientists analysed chemical changes to the ancient humans’ DNA to reveal broad, Neanderthal-like facial features.

doi: 10.1038/d41586-019-02820-0

The ecologist who wants to map everything p.478

doi: 10.1038/d41586-019-02846-4

The potent effects of Japan’s stem-cell policies p.482

doi: 10.1038/d41586-019-02847-3

Enigmatic origin of diamond-bearing rocks revealed p.498

doi: 10.1038/d41586-019-02808-w

Dangerous liaisons as tumour cells form synapses with neurons p.499

Why brain tumours progress rapidly is unclear. The finding that such cancer cells form synaptic connections with neurons uncovers an interaction that accelerates tumour growth rate and lethality.

doi: 10.1038/d41586-019-02746-7

Concerns that captive breeding affects the ability of monarch butterflies to migrate p.501

Monarch butterflies’ ability to migrate over long distances is impressive. Evidence that some monarchs reared in captivity have impaired migratory skills compared with wild monarchs has conservation implications.

doi: 10.1038/d41586-019-02644-y

The structure of a T-cell mechanosensor p.502

T-cell receptors orchestrate immune-system responses against infection and cancer. A structure of an entire T-cell receptor complex clarifies its assembly and signalling, and sheds light on its dynamic ligand recognition.

doi: 10.1038/d41586-019-02646-w

X-rays glimpse solid hydrogen’s structure p.504

doi: 10.1038/d41586-019-02811-1

Graphene and two-dimensional materials for silicon technology p.507

doi: 10.1038/s41586-019-1573-9

Multivalent anions as universal latent electron donors p.519

doi: 10.1038/s41586-019-1575-7

Synaptic proximity enables NMDAR signalling to promote brain metastasis p.526

doi: 10.1038/s41586-019-1576-6

Glutamatergic synaptic input to glioma cells drives brain tumour progression p.532

doi: 10.1038/s41586-019-1564-x

Electrical and synaptic integration of glioma into neural circuits p.539

doi: 10.1038/s41586-019-1563-y

Structural basis of assembly of the human T cell receptor–CD3 complex p.546

doi: 10.1038/s41586-019-1537-0

Coherent spin-state transfer via Heisenberg exchange p.553

doi: 10.1038/s41586-019-1566-8

Ultrahigh-pressure isostructural electronic transitions in hydrogen p.558

doi: 10.1038/s41586-019-1565-9

A 16-step synthesis of the isoryanodane diterpene (+)-perseanol p.563

doi: 10.1038/s41586-019-1580-x

Deep learning for multi-year ENSO forecasts p.568

doi: 10.1038/s41586-019-1559-7

Aridity is expressed in river topography globally p.573

doi: 10.1038/s41586-019-1558-8

Kimberlites reveal 2.5-billion-year evolution of a deep, isolated mantle reservoir p.578

doi: 10.1038/s41586-019-1574-8

Wilderness areas halve the extinction risk of terrestrial biodiversity p.582

doi: 10.1038/s41586-019-1567-7

A middle Cambrian arthropod with chelicerae and proto-book gills p.586

doi: 10.1038/s41586-019-1525-4

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome p.590

doi: 10.1038/s41586-019-1551-2

α-Ketoglutarate links p53 to cell fate during tumour suppression p.595

doi: 10.1038/s41586-019-1577-5

The fundamental role of chromatin loop extrusion in physiological V(D)J recombination p.600

doi: 10.1038/s41586-019-1547-y

eIF5B gates the transition from translation initiation to elongation p.605

doi: 10.1038/s41586-019-1561-0

Low-barrier hydrogen bonds in enzyme cooperativity p.609

doi: 10.1038/s41586-019-1581-9