Volume 573 Issue 7772



News Features

News & Views

A recipe book for cell types in the human brain p.36

Whether cell types in the brain have been conserved during evolution is not clear. A comparison of the molecular recipes that define brain cell types in humans and mice reveals similarities and differences between species.

doi: 10.1038/d41586-019-02343-8

Inhibitory protein puts a lid on an epigenetic marker p.38

Two reports examine how a protein complex that adds transcription-repressing marks to histone proteins is potently inhibited by the protein EZHIP during the maturation of sperm and egg cells and in a type of brain cancer.

doi: 10.1038/d41586-019-02521-8

Pressure regulates immune-cell function p.41

Immune cells called monocytes enter the lung during infection. Whether they help to launch a defence response is affected by the pressure encountered there, which is sensed by an ion channel called PIEZO1.

doi: 10.1038/d41586-019-02339-4