Volume 566 Issue 7743

Editorials

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News & Views

One rogue agent suffices for genomic chaos p.188

Genetic instability is a hallmark of cancer cells, and occurs when genes required for genomic maintenance are inactivated. It emerges that altering just one of the two copies of certain genes can drive genetic instability in yeast.

doi: 10.1038/d41586-019-00260-4

Resilient meerkats p.190

How do meerkat populations respond to extreme climatic variations?

doi: 10.1038/d41586-019-00530-1

Bigger is better in virtual drug screens p.193

A system has been devised that computationally screens hundreds of millions of drug candidates — all of which can be made on demand — against biological targets. This could help to make drug discovery more efficient.

doi: 10.1038/d41586-019-00145-6

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