Volume 558 Issue 7709


Reform the Antarctic Treaty p.161

Political protection for the planet’s last great wilderness is no longer fit for purpose. Make its governance democratic: scrap the veto that lets individual interests rule.

doi: 10.1038/d41586-018-05368-7


News Features

News & Views

Tumour tamed by transfer of one T cell p.193

The T cells of the immune system can be engineered to target a tumour, but why some people respond better than others to such therapy is unclear. One patient’s striking response to treatment now offers some clues.

doi: 10.1038/d41586-018-05251-5

How humans and rising seas affect each other p.196

The Paris climate agreement aims to limit global warming to no more than 2 °C. An analysis suggests that this will greatly reduce the risks of sea-level rise for coastal communities, but that it will take time to see the benefit.

doi: 10.1038/d41586-018-05366-9

Transcription regulation enters a new phase p.197

A subunit of the enzymatic complex P-TEFb can induce compartmentalization of proteins into liquid-like droplets in cells. This phase separation might help P-TEFb to promote gene transcription.

doi: 10.1038/d41586-018-05244-4