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Pulsars seen through a new lens p.494

Radio waves produced by cosmic lighthouses called pulsars are distorted by surrounding material. Observations show that this material can act as a lens, focusing the waves and boosting the brightness of the pulsar.

doi: 10.1038/d41586-018-05185-y

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Rethinking WNT signalling p.495

The identification of genetic mutations that can hinder the development of human limbs has led to the discovery of an unanticipated mode of regulation for the WNT signalling pathway during limb development.

doi: 10.1038/d41586-018-04820-y

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The cost of a warming climate p.498

A study finds that meeting climate-change mitigation targets will lead to a substantial reduction in economic damages. Here, economists present opposing views on the approach used by studies such as this one.

doi: 10.1038/d41586-018-05198-7

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Pancreatic cancer foiled by a switch of tumour subtype p.500

Mutations in the gene KDM6A drive an aggressive subtype of pancreatic cancer by causing repositioning of an enzyme complex that modifies histone proteins associated with DNA, leading to altered gene expression.

doi: 10.1038/d41586-018-05129-6

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Plasmon propagation pushed to the limit p.501

Excitations called plasmons have the potential to miniaturize photonic devices, but are often short-lived. Microscopy reveals that plasmons in the material graphene can overcome this limitation at low temperatures.

doi: 10.1038/d41586-018-05190-1

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Articles

Letters

Fundamental limits to graphene plasmonics p.530

The fundamental limits to plasmon damping in graphene are determined using nanoscale infrared imaging at cryogenic temperatures, and plasmon polaritons are observed to propagate over 10 micrometres in high-mobility encapsulated graphene.

doi: 10.1038/s41586-018-0136-9

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Self-reporting and self-regulating liquid crystals p.539

Liquid crystals are used to self-report and self-regulate either continuous or transient release of droplets or microparticles trapped within them in response to thermal, chemical, mechanical or biological stimuli.

doi: 10.1038/s41586-018-0098-y

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Mxra8 is a receptor for multiple arthritogenic alphaviruses p.570

The cell adhesion molecule Mxra8 is identified as a receptor for multiple arthritogenic alphaviruses such as chikungunya virus, and anti-Mxra8 monoclonal antibodies are shown to reduce rates of chikungunya virus infection in mice and a range of human cells.

doi: 10.1038/s41586-018-0121-3

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Structural basis for gating pore current in periodic paralysis p.590

Crystal structures and molecular dynamics simulations of voltage-gated sodium channels containing mutations that cause hypokalaemic and normokalaemic periodic paralysis indicate the pathogenic mechanisms of these conditions and suggest a target for the design of potential therapeutic and symptomatic drugs.

doi: 10.1038/s41586-018-0120-4

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