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Volume 556 Issue 7701

Editorials

News

News Features

How to blow up a star p.287

Supernova simulations are resolving a 50-year-old mystery about stellar death throes.

doi: 10.1038/d41586-018-04601-7

News & Views

Immune memory in the brain p.312

The brain’s resident immune cells retain a long-lasting memory of peripheral inflammation. This memory can influence the response to stroke and the progression of Alzheimer’s disease in mouse models.

doi: 10.1038/d41586-018-03800-6

Peptides used to make light-twisting nanoparticles p.313

The growth of gold nanoparticles has been manipulated using amino acids and peptides to produce twisted structures that alter the rotation of light. The method could simplify the development of optical devices.

doi: 10.1038/d41586-018-04205-1

When sex differences lead to extinction p.315

There are striking differences between the male and female forms of some species. A study of marine fossils finds that such differences come at the cost of an increased risk of extinction.

doi: 10.1038/d41586-018-04059-7

Electronics and photonics united p.316

A method for integrating photonic devices with state-of-the-art nanoelectronics overcomes previous limitations. The approach shows promise for realizing high-speed, low-power optoelectronic technology.

doi: 10.1038/d41586-018-04443-3

A stockpile of antiviral defences p.318

The full list of weapons used by bacteria against viruses is not known. A computational approach has uncovered nine previously unidentified antiviral systems, encoded by genes near known defence genes in bacterial genomes.

doi: 10.1038/d41586-018-04367-y

Bounteous black holes at the Galactic Centre p.319

X-ray observations have revealed a dozen stellar-mass black holes at the centre of the Galaxy, implying that there are thousands more to be found. The discovery confirms a fundamental prediction of stellar dynamics.

doi: 10.1038/d41586-018-04341-8

Articles

Functional circuit architecture underlying parental behaviour p.326

Galanin-expressing neurons in the medial preoptic area coordinate different aspects of motor, motivational, hormonal and social behaviour associated with parenting by projecting to different brain regions depending on the type of behaviour and sex and reproductive state of mice.

doi: 10.1038/s41586-018-0027-0

Genome evolution across 1,011 Saccharomyces cerevisiae isolates OPEN p.339

Whole-genome sequencing of 1,011 natural isolates of the yeast Saccharomyces cerevisiae reveals its evolutionary history, including a single out-of-China origin and multiple domestication events, and provides a framework for genotype–phenotype studies in this model organism.

doi: 10.1038/s41586-018-0030-5

Letters