p.5
Trees and shrubs could be less fussy about the climate than scientists thought. That might be good news as the planet warms.doi: 10.1038/d41586-017-07841-1
Volume 552 Issue 7683
리서치 하이라이트
표지 기사： 자가 조립 DNA 오리가미 어레이를 이용한 모나리자 그림
지구의 현재 에너지 수지에 의해서 추정할 수 있는 미래의 글로벌 온난화
유비쿼틴 기질과 복합체를 형성한 PINK 1에 대한 구조 분석
tRNA에서 유래한 작은 RNA 단편을 통한 리보솜 생합성 조절
수증기 또는 초임계 유체 환경에서 만들어졌을 것으로 추정되는 화성의 진흙 성분
아프리카에 서식하는 말라리아 매개 모기 Anopheles gambiae의 유전적 다양성 분석
RIFIN을 통한 말라리아 기생충의 면역 회피 작용
모체의 연령에 의해서 조절되는 자손 세대에서의 표현형 다양성
T세포성 비호지킨성 림프종을 억제하는 PD-1
컨텐츠
Editorials
p.5
The Nature Awards for Mentoring in Science show that it is crucial to support researchers in leading their groups well.doi: 10.1038/d41586-017-07840-2
p.6
Scientists must continue to play their part in pointing out the potential environmental dangers.doi: 10.1038/d41586-017-08214-4
News
p.13
Thousands of ancient Native American sites to lose protections.doi: 10.1038/d41586-017-07794-5
p.14
Embryos found in some fossil eggs suggest that hatchlings struggled to fly.doi: 10.1038/nature.2017.23049
p.15
Chinese scientists find all the genetic building blocks of SARS in a single population of horseshoe bats.doi: 10.1038/d41586-017-07766-9
p.16
Space agencies are planning a Deep Space Gateway to orbit the Moon.doi: 10.1038/d41586-017-07869-3
p.17
Negotiations to reduce journal prices and promote open access are progressing slowly.doi: 10.1038/d41586-017-07817-1
News Features
p.20
High-pressure experiments explore what it might take to make exoplanets habitabledoi: 10.1038/d41586-017-07844-y
News & Views
p.34
DNA can be designed to self-assemble into target shapes, but the size and quantity of objects that can be prepared have been limited. Methods to overcome these problems have now been found.doi: 10.1038/d41586-017-07690-y
p.35
The relative roles of biological and environmental factors in driving evolutionary change have been unclear. Now fossil analysis shows that their action depends on where an animal group is in its evolutionary trajectory.doi: 10.1038/d41586-017-07440-0
p.37
Martian clays present a conundrum: the models proposed to explain their formation require conditions that are not predicted by computational climate simulations. Experiments now suggest an alternative scenario.doi: 10.1038/d41586-017-07661-3
p.38
Structures of an unusual enzymatic domain in PINK1 provide insights into how this protein regulates the function of organelles called mitochondria, and how mutations in PINK1 contribute to Parkinson’s disease.doi: 10.1038/d41586-017-07691-x
p.40
Materials that consist of just one or a few layers of atoms could have a range of useful applications. Computer simulations now show that the element tellurium might form three such phases, and that they have potentially useful properties.doi: 10.1038/d41586-017-07159-y
p.41
Inhibiting the protein PD-1 can activate T cells that trigger immune responses against tumour cells. But it emerges that, in mice, this immunotherapy exacerbates a cancer that involves the T cells themselves. See Letter p.121doi: 10.1038/nature24759
p.42
In 1997, it was demonstrated that quantum states can be teleported from one location to a distant one. The discovery had huge consequences for the development of quantum communication and computing.doi: 10.1038/d41586-017-07689-5
Articles
p.45
Models show that several aspects of Earth’s top-of-atmosphere energy budget and the magnitude of projected global warming are correlated, enabling us to infer that future warming has been underestimated.doi: 10.1038/nature24672
p.51
Stabilization of a transient protein kinase–substrate complex using a nanobody provides molecular details about how the Parkinson’s disease-linked protein kinase PINK1 phosphorylates ubiquitin, and suggests new pharmacological strategies.doi: 10.1038/nature24645
p.57
A 22-nucleotide fragment of a transfer RNA regulates translation by binding to the mRNA of a ribosomal protein and increasing its expression, and downregulation of the fragment in patient-derived liver tumour cells reduces tumour growth in mice.doi: 10.1038/nature25005
Letters
p.63
A direct measurement of cosmic-ray electrons and positrons with unprecedentedly high energy resolution reveals a spectral break at about 0.9 teraelectronvolts, confirming the evidence found by previous indirect measurements.doi: 10.1038/nature24475
p.67
Simple assembly rules applied recursively in a multistage assembly process enable the creation of DNA origami arrays with sizes of up to 0.5 square micrometres and with arbitrary patterns.doi: 10.1038/nature24655
p.72
DNA bricks with binding domains of 13 nucleotides instead of the typical 8 make it possible to self-assemble gigadalton-scale, three-dimensional nanostructures consisting of tens of thousands of unique components.doi: 10.1038/nature24648
p.78
By using DNA sequence information to encode the shapes of DNA origami building blocks, shape-programmable assemblies can be created, with sizes and complexities similar to those of viruses.doi: 10.1038/nature24651
p.84
All necessary strands for DNA origami can be created in a single scalable process by using bacteriophages to generate single-stranded precursor DNA containing the target sequences interleaved with self-excising DNA enzymes.doi: 10.1038/nature24650
p.88
Many Martian clays formed when Mars’ primary crust reacted with a water/carbon dioxide steam or supercritical atmosphere and subsequent impacts and volcanism caused the distribution of clay exposures seen today.doi: 10.1038/nature24657
p.92
Focusing attention on the expansion of taxa, rather than their survival, resolves the apparent contradiction between seemingly deterministic patterns of waxing and waning of taxa over time and the randomness of extinction implied by the Red Queen’s hypothesis.doi: 10.1038/nature24656
p.96
Genome sequencing analyses from 765 specimens of Anopheles gambiae and Anopheles coluzzii from 15 locations across Africa characterize patterns of gene flow and variations in population size, and provide a resource for studying the evolution of natural malaria vector populations.doi: 10.1038/nature24995
p.101
Proteins expressed on the surfaces of erythrocytes infected with Plasmodium falciparum help the parasite to evade the host immune system by acting as ligands for immune inhibitory receptors and thereby downregulating the immune response.doi: 10.1038/nature24994
p.106
Maternal age is found to be a major source of phenotypic variation in isogenic C. elegans populations living in a controlled environment, with the progeny of young mothers impaired for multiple fitness traits.doi: 10.1038/nature25012
p.110
Fibroblast-specific IL-11 expression causes heart and kidney fibrosis and organ failure, whereas IL-11 inhibition prevents fibroblast activation and organ fibrosis, indicating that IL-11 inhibition is a potential therapeutic strategy to treat fibrotic diseases.doi: 10.1038/nature24676
p.116
The inactivation of DNA mismatch repair in cancer cells produces dynamic mutational profiles and generates neoantigens, which result in improved immune surveillance against these cells.doi: 10.1038/nature24673
p.121
Loss of the PD-1 receptor promotes the development of T cell non-Hodgkin lymphomas by modulating oncogenic signalling pathways, and blocking these pathways reduces tumourigenesis.doi: 10.1038/nature24649
p.126
N
doi: 10.1038/nature24678
p.132
A genetically encoded platform can produce chiral organoboranes in bacteria with high turnover, enantioselectivity and chemoselectivity, and can be tuned and configured through DNA manipulation.doi: 10.1038/nature24996
