Volume 551 Number 7679

Editorials

Skin regeneration with insights p.141

A feat in stem-cell therapy highlights what can be achieved when basic and clinical research combine to advance biological understanding and treatment.

doi: 10.1038/551141a

News

News Features

News & Views

Neurons recorded en masse p.172

A silicon probe that is inserted into the mouse brain can precisely measure the activity of about 200 individual neurons simultaneously. This tool should improve our ability to study functional neuronal circuitry. See Letter p.232

doi: 10.1038/551172a

The star that would not die p.173

An event that initially resembled an ordinary supernova explosion continued to erupt brightly for more than 600 days. Standard theoretical models cannot explain the event's properties. See Letter p.210

doi: 10.1038/551173a

Shrinking maps of RNA modifications p.174

The presence of N1 methyl groups on adenine bases was thought to be widespread in messenger RNAs. It now seems that these modifications are much less prevalent, and occur on mRNAs that structurally mimic transfer RNA. See Letter p.251

doi: 10.1038/nature24156

Organic dyes for deep bioimaging p.176

Small-molecule organic dyes that fluoresce in the short-wave infrared region of the spectrum could improve the resolution of in vivo bioimaging methods. Such dyes have now been made by adapting those that fluoresce visible light.

doi: 10.1038/nature24755

Mixed up at the sea floor p.178

Circulation of the ocean's densest waters modulates millennial-scale shifts in climate. Contrary to conventional wisdom, a study finds that the shape of the sea floor constrains where these waters rise towards the surface. See Article p.181

doi: 10.1038/551178b

A genetic cause of age-related decline p.179

Genetic variation in a neuropeptide signalling pathway regulates age-related declines in health in nematode worms. This discovery points to a mechanism that influences individual differences in ageing. See Article p.198

doi: 10.1038/551179a

Articles

Creation of forest edges has a global impact on forest vertebrates p.187

Fragmentation of forest ecosystems produces forest edges, which affect the distribution of many analysed vertebrate species; smaller-bodied amphibians, larger reptiles and medium-sized mammals experience a larger reduction in suitable habitat than other forest-core species.

doi: 10.1038/nature24457

Letters

Role of stacking disorder in ice nucleation p.218

Stacking-disordered ice crystallites are shown to have an ice nucleation rate much higher than predicted by classical nucleation theory, which needs to be taken into account in cloud modelling.

doi: 10.1038/nature24279

Detecting evolutionary forces in language change p.223

Analyses of digital corpora of annotated texts reveal the influence of stochastic drift versus selection in grammatical shifts in English and provide a general method for quantitatively testing theories of language change.

doi: 10.1038/nature24455

Nutrient co-limitation at the boundary of an oceanic gyre p.242

Nutrient amendment experiments at the boundary of the South Atlantic gyre reveal extensive regions in which nitrogen and iron are co-limiting, with other micronutrients also approaching co-deficiency; such limitations potentially increase phytoplankton community diversity.

doi: 10.1038/nature24063