Too many academics study the same people p.141
Researchers should recognize communities that feel over-researched and under-rewarded.doi: 10.1038/551141b
Volume 551 Issue 7679
Editorials
Skin regeneration with insights p.141
A feat in stem-cell therapy highlights what can be achieved when basic and clinical research combine to advance biological understanding and treatment.doi: 10.1038/551141a
Grant recipients can still give objective advice p.142
The US environment agency should not ban researchers it funds from its advisory boards.doi: 10.1038/551142a
News
Genetically modified apple reaches US stores, but will consumers bite? p.149
Success for the ‘Arctic apple’ could herald a new wave of lab-grown foods.doi: 10.1038/551149a
Pay for US postdocs varies wildly by institution p.150
Analysis of universities' salary data suggests major disparities in pay for early-career researchers.doi: 10.1038/nature.2017.22932
Newly discovered orangutan species is also the most endangered p.151
The first new species of great ape described in more than eight decades faces threats to its habitat.doi: 10.1038/nature.2017.22934
Energy researcher sues the US National Academy of Sciences for millions of dollars p.152
Rare move stems from a conflict over two journal articles about renewable energy.doi: 10.1038/nature.2017.22944
US government report says that climate change is real — and humans are to blame p.152
Conclusions of climate-change science analysis are at odds with US President Donald Trump’s policies.doi: 10.1038/nature.2017.22958
Dark-matter hunt fails to find the elusive particles p.153
Physicists begin to embrace alternative explanations for the missing material.doi: 10.1038/551153a
News Features
The bitter battle over the world’s most popular insecticides p.156
As regulators consider a ban on neonicotinoids, debate rages over the harm they cause to bees.doi: 10.1038/551156a
News & Views
Neurons recorded en masse p.172
A silicon probe that is inserted into the mouse brain can precisely measure the activity of about 200 individual neurons simultaneously. This tool should improve our ability to study functional neuronal circuitry. See Letter p.232doi: 10.1038/551172a
The star that would not die p.173
An event that initially resembled an ordinary supernova explosion continued to erupt brightly for more than 600 days. Standard theoretical models cannot explain the event's properties. See Letter p.210doi: 10.1038/551173a
Shrinking maps of RNA modifications p.174
The presence of Ndoi: 10.1038/nature24156
Organic dyes for deep bioimaging p.176
Small-molecule organic dyes that fluoresce in the short-wave infrared region of the spectrum could improve the resolution of in vivo bioimaging methods. Such dyes have now been made by adapting those that fluoresce visible light.doi: 10.1038/nature24755
Ice niceties p.178
doi: 10.1038/551178a
Mixed up at the sea floor p.178
Circulation of the ocean's densest waters modulates millennial-scale shifts in climate. Contrary to conventional wisdom, a study finds that the shape of the sea floor constrains where these waters rise towards the surface. See Article p.181doi: 10.1038/551178b
A genetic cause of age-related decline p.179
Genetic variation in a neuropeptide signalling pathway regulates age-related declines in health in nematode worms. This discovery points to a mechanism that influences individual differences in ageing. See Article p.198doi: 10.1038/551179a
Articles
Abyssal ocean overturning shaped by seafloor distribution p.181
The geometry of the ocean floor sets key regime transitions in the circulation of deep ocean waters.doi: 10.1038/nature24472
Creation of forest edges has a global impact on forest vertebrates p.187
Fragmentation of forest ecosystems produces forest edges, which affect the distribution of many analysed vertebrate species; smaller-bodied amphibians, larger reptiles and medium-sized mammals experience a larger reduction in suitable habitat than other forest-core species.doi: 10.1038/nature24457
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis p.192
Astrocyte morphogenesis depends on interactions between astrocytic neuroligins and neuronal neurexins.doi: 10.1038/nature24638
Genetic variation in glia–neuron signalling modulates ageing rate p.198
Identifying the gene polymorphisms that are the foundations of variation in glia–neuron signalling in Caenorhabditis elegans provides insight into highly variable age-related declines in worm behaviours.doi: 10.1038/nature24463
Structures of transcription pre-initiation complex with TFIIH and Mediator p.204
Cryo-electron microscopy structures of the yeast pre-initiation complex (PIC) and its complex with core Mediator provide insights into the opening of promoter DNA and the initiation of transcription.doi: 10.1038/nature24282
Letters
Energetic eruptions leading to a peculiar hydrogen-rich explosion of a massive star p.210
Observations of an event (several energetic eruptions leading to a terminal explosion that is surprisingly hydrogen-rich) with the spectrum of a supernova do not match with other observations of supernovae.doi: 10.1038/nature24030
History-independent cyclic response of nanotwinned metals p.214
In copper components containing highly oriented nanotwins, correlated ‘necklace’ dislocations moving back and forth offer an unusually fatigue-resistant response to engineering stress.doi: 10.1038/nature24266
Role of stacking disorder in ice nucleation p.218
Stacking-disordered ice crystallites are shown to have an ice nucleation rate much higher than predicted by classical nucleation theory, which needs to be taken into account in cloud modelling.doi: 10.1038/nature24279
Detecting evolutionary forces in language change p.223
Analyses of digital corpora of annotated texts reveal the influence of stochastic drift versus selection in grammatical shifts in English and provide a general method for quantitatively testing theories of language change.doi: 10.1038/nature24455
Kctd13 deletion reduces synaptic transmission via increased RhoA p.227
Experimental evidence that global Kctd13 reduction leads to increased RhoA levels that reduce synaptic transmission, implicating RhoA as a potential therapeutic target for neuropsychiatric disorders associated with copy-number variants that include KCTD13.doi: 10.1038/nature24470
Fully integrated silicon probes for high-density recording of neural activity p.232
New silicon probes known as Neuropixels are shown to record from hundreds of neurons simultaneously in awake and freely moving rodents.doi: 10.1038/nature24636
Ultra-selective looming detection from radial motion opponency p.237
The discovery of a visual-looming-sensitive neuron, LPLC2, that provides input to the Drosophila escape pathway, and uses dendrites patterned to integrate directionally selective inputs to selectively encode outward motion.doi: 10.1038/nature24626
Nutrient co-limitation at the boundary of an oceanic gyre p.242
Nutrient amendment experiments at the boundary of the South Atlantic gyre reveal extensive regions in which nitrogen and iron are co-limiting, with other micronutrients also approaching co-deficiency; such limitations potentially increase phytoplankton community diversity.doi: 10.1038/nature24063
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition p.247
Cancer persister cells, which survive cytotoxic treatments, are shown to be sensitive to inhibition of the lipid hydroperoxidase GPX4.doi: 10.1038/nature24297
The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution p.251
Transcriptome-wide mapping of N1-methyladenosine (m1A) at single-nucleotide resolution reveals m1A to be scarce in cytoplasmic mRNA, to inhibit translation, and to be highly dynamic at a single site in a mitochondrial mRNA.doi: 10.1038/nature24456
