Frédéric Chopin’s telltale heart p.5
Scientists have written another chapter in the curious case of the composer’s heart. But it is unlikely to be the end of the story.doi: 10.1038/551005a
Volume 551 Issue 7678
리서치 하이라이트
표지 기사： 두 개의 중성자 별이 융합되면서 발생하는 킬로노바로부터 유래한 광학적 방출 관측
60,000세대를 거치는 동안 일어나는 분자생물학적 진화 과정에 대한 분석
코헤신 제거를 통해서 밝혀진 염색체 구성에 대한 두 가지 서로 다른 모드
65개의 새로운 유방암 발병 위험 유전자 발견
유성 생식 단계의 말라리아 기생충의 특징에 대한 단일 세포 RNA 염기서열 분석
섬유아세포에서 심근 세포로의 전환을 유도하는 단일 세포 트랜스트립톰
항암 및 항바이러스 활성을 가진 자연 살해 세포에서의 체크포인트 역할을 하는 IL-1R8
TCA 사이클에서 글루코오스만큼 중요한 역할을 하는 것으로 밝혀진 전신 젖산 레벨
컨텐츠
Editorials
Lower emissions on the high seas p.5
Global regulations to limit carbon dioxide from the shipping industry are overdue.doi: 10.1038/551005b
Citation is not the only impact p.6
A look at what we have published highlights the variety of editorial judgements in selecting and assessing papers.doi: 10.1038/551006a
News
Ageing satellites put crucial sea-ice climate record at risk p.13
Scientists scramble to avert disruption to data set that has tracked polar ice since the late 1970s.doi: 10.1038/nature.2017.22907
Geneticists are starting to unravel evolution's role in mental illness p.15
Hints emerge that past environments could have influenced psychiatric disorders.doi: 10.1038/nature.2017.22914
Plans to promote German research excellence come under fire p.15
Critics say selection process for high-stakes funding programme is flawed.doi: 10.1038/551015a
US March for Science group faces growing pains p.16
A group of volunteers claims that the organization that spearheaded global protests in April has been unduly secretive about its management practices.doi: 10.1038/nature.2017.22909
Camouflage plumage patterns offer clue to dinosaur’s habitat p.17
Feathered carnivore was dark on top and light underneath, with a raccoon-like face.doi: 10.1038/nature.2017.22891
Genomic studies track early hints of cancer p.18
Pilot projects aim to pinpoint how benign tumours turn into lung, breast, prostate and pancreatic cancers.doi: 10.1038/nature.2017.22911
News Features
The new thermodynamics: how quantum physics is bending the rules p.20
Experiments are starting to probe the limits of the classical laws of thermodynamics.doi: 10.1038/551020a
News & Views
A golden binary p.36
The discovery of gravitational waves from a neutron-star merger and the detection of the event across the electromagnetic spectrum give insight into many aspects of gravity and astrophysics. See Letter p.64, p.67, p.71, p.75 & p.80doi: 10.1038/nature24153
The surprising history of an antioxidant p.37
What came first: oxygen-producing photosynthesis, or compounds that protect cells from oxygen-induced damage? It emerges that one such compound might have been produced in microbes before Earth's oxygenation.doi: 10.1038/551037a
How to build a cohesive genome in 3D p.38
Removing the protein complex cohesin from chromosomes destroys one layer of the genome's 3D structure but leaves another intact. Genome structure is therefore built by independent processes that work together. See Letter p.51doi: 10.1038/nature24145
Quarks fuse to release energy p.40
In nuclear fusion, energy is produced by the rearrangement of protons and neutrons. The discovery of an analogue of this process involving particles called quarks has implications for both nuclear and particle physics. See Letter p.89doi: 10.1038/551040a
A change of fate for nerve repair p.41
Schwann cells support neuronal signalling. The discovery that these cells become dramatically reprogrammed after nerve injury, adopting migratory characteristics that promote repair, highlights the plasticity of mature cell types.doi: 10.1038/551041a
No escape from the tangled bank p.42
Ecological interactions emerge spontaneously in an experimental study of bacterial populations cultured for 60,000 generations, and sustain rapid evolution by natural selection. See Letter p.45doi: 10.1038/nature24152
Articles
The dynamics of molecular evolution over 60,000 generations p.45
Using data from sixty thousand generations of the E. coli long-term evolution experiment, the authors shed new light on the processes that govern molecular evolution.doi: 10.1038/nature24287
Two independent modes of chromatin organization revealed by cohesin removal p.51
Depletion of chromosome-associated cohesin leads to loss of topologically associating domains in interphase chromosomes, without affecting segregation into compartments, and instead, it unmasks a finer compartment structure that reflects local chromatin and transcriptional activity.doi: 10.1038/nature24281
Structure of phycobilisome from the red alga Griffithsia pacifica p.57
Single-particle cryo-electron microscopy is used to resolve the structure of the phycobilisome, a 16.8-megadalton light-harvesting megacomplex, from the red alga Griffithsia pacifica at a resolution of 3.5 Å.doi: 10.1038/nature24278
Letters
Optical emission from a kilonova following a gravitational-wave-detected neutron-star merger p.64
Optical to near-infrared observations of a transient coincident with the detection of the gravitational-wave signature of a binary neutron-star merger and a low-luminosity short-duration γ-ray burst are presented and modelled.doi: 10.1038/nature24291
Spectroscopic identification of r-process nucleosynthesis in a double neutron-star merger p.67
Observations of the transient associated with the gravitational-wave event GW170817 and γ-ray burst GRB 170817A reveal a bright kilonova with fast-moving ejecta, including lanthanides synthesized by rapid neutron capture.doi: 10.1038/nature24298
The X-ray counterpart to the gravitational-wave event GW170817 p.71
Detection of X-ray emission at a location coincident with the kilonova transient of the gravitational-wave event GW170817 provides the missing observational link between short γ-ray bursts and gravitational waves from neutron-star mergers.doi: 10.1038/nature24290
A kilonova as the electromagnetic counterpart to a gravitational-wave source p.75
Observations and modelling of an optical transient counterpart to a gravitational-wave event and γ-ray burst reveal that neutron-star mergers produce gravitational waves and radioactively powered kilonovae, and are a source of heavy elements.doi: 10.1038/nature24303
Origin of the heavy elements in binary neutron-star mergers from a gravitational-wave event p.80
Modelling the electromagnetic emission of kilonovae enables the mass, velocity and composition (with some heavy elements) of the ejecta from a neutron-star merger to be derived from the observations.doi: 10.1038/nature24453
A gravitational-wave standard siren measurement of the Hubble constant p.85
The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.doi: 10.1038/nature24471
Quark-level analogue of nuclear fusion with doubly heavy baryons p.89
Two singly charmed baryons can fuse into the recently discovered doubly charmed baryon and a neutron through an exothermic reaction analogous to the nuclear fusion between deuterium and tritium.doi: 10.1038/nature24289
Association analysis identifies 65 new breast cancer risk loci p.92
Association analysis identifies 65 new breast cancer risk loci, predicts target genes for known risk loci and demonstrates a strong overlap with somatic driver genes in breast tumours.doi: 10.1038/nature24284
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites p.95
Highly parallel single-cell transcriptome profiling of Plasmodium falciparum blood stages provides insight into the role AP2-G plays in early sexual development of this eukaryotic pathogen.doi: 10.1038/nature24280
Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte p.100
Single-cell transcriptomics analyses of cell intermediates during the reprogramming from fibroblast to cardiomyocyte were used to reconstruct the reprogramming trajectory and to uncover intermediate cell populations, gene pathways and regulators involved in this process.doi: 10.1038/nature24454
Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation p.105
TGFβ signalling regulates T helper 17 (TH17) cell differentiation by reversing SKI–SMAD4-mediated suppression of RORγt, revealing a potential therapeutic target for treating TH17-related diseases.doi: 10.1038/nature24283
IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity p.110
Interleukin-1 receptor 8 (IL-1R8), a negative regulator of the IL-1 family of cytokines, restrains the activity of natural killer (NK) cells, suggesting that IL-1R8 acts as a checkpoint regulator of NK cell activation and that its blockade may be of use in cancer therapy.doi: 10.1038/nature24293
Glucose feeds the TCA cycle via circulating lactate p.115
Metabolic flux analysis in mice reveals that lactate often acts as the primary carbon source for the tricarboxylic acid cycle both in normal tissues and in tumour microenvironments.doi: 10.1038/nature24057
A global resource allocation strategy governs growth transition kinetics of Escherichia coli p.119
A new approach to modelling bacterial growth removes the need to know kinetic parameters for metabolic and regulatory processes and can be used to model adaptive processes such as antibiotic responses and ecological dynamics.doi: 10.1038/nature24299
Embryonic epigenetic reprogramming by a pioneer transcription factor in plants p.124
The seed-specific transcription factor LEC1 promotes an active chromatin state at the floral repressor FLC and activates its expression in the Arabidopsis pro-embryo, thus reversing the winter cold-induced silenced state that is inherited from gametes.doi: 10.1038/nature24300
