Using free-floating DNA to detect lung cancer brings benefits to researchers and patients alike.
They say they don't have the time or incentives to do research — and that’s dangerous for translational medicine.
Major investment in regenerative medicine enters its last stage — and the money might run out before treatments are ready.
November tremor sparked slow, deep movements in Earth’s crust that increase the chances of a similar severe quake within a year.
Protests sparked by the destruction of three key fossil-hunting areas result in a temporary halt of phosphate mining.
Nature reported from marches in cities including Sydney, Washington DC and Paris, as people took to the streets in support of science.
How Peruvian coastal deserts respond to rains will aid future disaster response.
Superfast imaging techniques are giving researchers their best views yet of what happens in the atomic world.
News & Views
Oldfield mice and deer mice differ in their parental care, most dramatically in the behaviour of fathers. A study reveals the genetic and neuronal contributions to variation in parental care. See Article p.434
The proton can contain pairs of elementary particles known as strange quarks. The contribution of these particles to the proton's electric-charge distribution and magnetic moment has been determined.
Humans are thought to have reached the Americas less than 15,000 years ago. But evidence of stone tool use on an animal carcass excavated in California points to a much earlier arrival of human relatives from the genus Homo. See Letter p.479
During the past few decades, the Sahara Desert has become even hotter. Satellite observations suggest that this warming has led to a rise in the frequency of extreme storms in the Sahel region of West Africa. See Letter p.475
Biological molecules are often imaged by attaching fluorescent labels — but only a few label types can be used at a time. A method that could smash the record for the number of labels that can be used together is now reported. See Letter p.465
A high-quality barley genome reveals a surprising compartmentalization of genes and repetitive sequences in chromosomes. This advance paves the way for improved genetic optimization of cereals. See Article p.427
The International Barley Genome Sequencing Consortium reports sequencing and assembly of a reference genome for barley, Hordeum vulgare.
Parental care in mice evolves through multiple genetic changes; one candidate is vasopressin, the reduced expression of which promotes parental nest-building behaviour in monogamous mice.
The cryo-electron microscopy structure of Saccharomyces cerevisiae Snf2 chromatin remodeller bound to a nucleosome and a proposed mechanism for DNA translocation by Snf2 are presented.
High-resolution structures of the thermostabilized human excitatory amino acid transporter EAAT1, alone or in association with its substrate or small molecule inhibitors, reveal architectural features of human SLC1 transporters and an allosteric mechanism of inhibition.
Simulations of a solar coronal jet driven by filament ejection demonstrate that magnetic reconnection underlies the energy release, implying that a universal ‘breakout’ model explains both tiny jets and huge mass ejections from the Sun.
A general simulation approach that can replicate, and in theory predict, the growth of a wide range of crystal types, including porous, molecular and ionic crystals, is demonstrated.
A method of producing superstrong yet ductile steels using cheaper and lighter alloying elements is described, based on minimization of the lattice misfit to achieve a maximal dispersion of nanoprecipitates, leading to ultimate precipitation strengthening.
Stimulated Raman scattering under electronic pre-resonance conditions, combined with a new palette of probes, enables super-multiplex imaging of molecular targets in living cells with very high vibrational selectivity and sensitivity.
The amount of coarse gravel transported out of the Himalayan mountains by rivers is insensitive to catchment size, because the majority of gravel sourced more than 100 kilometres upstream of the mountain front is abraded into sand before it reaches the Ganga Plain.
Since 1982, extreme daily rainfall in the western Sahel has increased persistently, owing to a warmer Sahara which has led to increased wind shear and an increase in intense storms.
Evidence of mastodon bone modifications for marrow extraction and/or tool production, found in the presence of hammerstones and anvils that showed use-wear and impact marks, suggest the presence of Homo in North America around 130 thousand years ago.
The archosaur species Teleocrater rhadinus, part of the new clade Aphanosauria, is an example of the earliest divergence of the avian stem lineage (Avemetatarsalia), the lineage that contains dinosaurs (including birds).
Treatment with plasma of an early developmental stage, human umbilical cord, revitalizes the hippocampus and improves cognitive function in aged mice.
The identification of homotypic SLAMF7 interactions responsible for haematopoietic tumour cell phagocytosis by macrophages when the inhibitory receptor/ligand interaction of SIRPα/CD47 is blocked therapeutically.
The distribution of cohesin in the mouse genome depends on CTCF, transcription and the cohesin release factor Wapl.